Neoplasms C00-D49 >

Note
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (
    ICD-10-CM Diagnosis Code C25.9

    Malignant neoplasm of pancreas, unspecified

      2016 2017 2018 Billable/Specific Code
    C25.9
    ).
Codes
ICD-10-CM Range C00-C14

Malignant neoplasms of lip, oral cavity and pharynx

  • C00 Malignant neoplasm of lip
  • C01 Malignant neoplasm of base of tongue
  • C02 Malignant neoplasm of other and unspecif...
  • C03 Malignant neoplasm of gum
  • C04 Malignant neoplasm of floor of mouth
  • C05 Malignant neoplasm of palate
  • C06 Malignant neoplasm of other and unspecif...
  • C07 Malignant neoplasm of parotid gland
  • C08 Malignant neoplasm of other and unspecif...
  • C09 Malignant neoplasm of tonsil
  • C10 Malignant neoplasm of oropharynx
  • C11 Malignant neoplasm of nasopharynx
  • C12 Malignant neoplasm of pyriform sinus
  • C13 Malignant neoplasm of hypopharynx
  • C14 Malignant neoplasm of other and ill-defi...
ICD-10-CM Range C15-C26

Malignant neoplasms of digestive organs

Type 1 Excludes
  • Kaposi's sarcoma of gastrointestinal sites (C46.4)
Type 2 Excludes
  • gastrointestinal stromal tumors (C49.A-)
  • C15 Malignant neoplasm of esophagus
  • C16 Malignant neoplasm of stomach
  • C17 Malignant neoplasm of small intestine
  • C18 Malignant neoplasm of colon
  • C19 Malignant neoplasm of rectosigmoid junct...
  • C20 Malignant neoplasm of rectum
  • C21 Malignant neoplasm of anus and anal cana...
  • C22 Malignant neoplasm of liver and intrahep...
  • C23 Malignant neoplasm of gallbladder
  • C24 Malignant neoplasm of other and unspecif...
  • C25 Malignant neoplasm of pancreas
  • C26 Malignant neoplasm of other and ill-defi...
ICD-10-CM Range C30-C39

Malignant neoplasms of respiratory and intrathoracic organs

Includes
  • malignant neoplasm of middle ear
Type 1 Excludes
  • C30 Malignant neoplasm of nasal cavity and m...
  • C31 Malignant neoplasm of accessory sinuses
  • C32 Malignant neoplasm of larynx
  • C33 Malignant neoplasm of trachea
  • C34 Malignant neoplasm of bronchus and lung
  • C37 Malignant neoplasm of thymus
  • C38 Malignant neoplasm of heart, mediastinum...
  • C39 Malignant neoplasm of other and ill-defi...
ICD-10-CM Range C40-C41

Malignant neoplasms of bone and articular cartilage

Includes
  • malignant neoplasm of cartilage (articular) (joint)
  • malignant neoplasm of periosteum
Type 1 Excludes
  • malignant neoplasm of bone marrow NOS (C96.9)
  • malignant neoplasm of synovia (C49.-)
  • C40 Malignant neoplasm of bone and articular...
  • C41 Malignant neoplasm of bone and articular...
ICD-10-CM Range C43-C44

Melanoma and other malignant neoplasms of skin

  • C43 Malignant melanoma of skin
  • C44 Other and unspecified malignant neoplasm...
  • C4A Merkel cell carcinoma
ICD-10-CM Range C45-C49

Malignant neoplasms of mesothelial and soft tissue

  • C45 Mesothelioma
  • C46 Kaposi's sarcoma
  • C47 Malignant neoplasm of peripheral nerves ...
  • C48 Malignant neoplasm of retroperitoneum an...
  • C49 Malignant neoplasm of other connective a...
ICD-10-CM Range C50-C50

Malignant neoplasms of breast

  • C50 Malignant neoplasm of breast
ICD-10-CM Range C51-C58

Malignant neoplasms of female genital organs

Includes
  • malignant neoplasm of skin of female genital organs
  • C51 Malignant neoplasm of vulva
  • C52 Malignant neoplasm of vagina
  • C53 Malignant neoplasm of cervix uteri
  • C54 Malignant neoplasm of corpus uteri
  • C55 Malignant neoplasm of uterus, part unspe...
  • C56 Malignant neoplasm of ovary
  • C57 Malignant neoplasm of other and unspecif...
  • C58 Malignant neoplasm of placenta
ICD-10-CM Range C60-C63

Malignant neoplasms of male genital organs

Includes
  • malignant neoplasm of skin of male genital organs
  • C60 Malignant neoplasm of penis
  • C61 Malignant neoplasm of prostate
  • C62 Malignant neoplasm of testis
  • C63 Malignant neoplasm of other and unspecif...
ICD-10-CM Range C64-C68

Malignant neoplasms of urinary tract

  • C64 Malignant neoplasm of kidney, except ren...
  • C65 Malignant neoplasm of renal pelvis
  • C66 Malignant neoplasm of ureter
  • C67 Malignant neoplasm of bladder
  • C68 Malignant neoplasm of other and unspecif...
ICD-10-CM Range C69-C72

Malignant neoplasms of eye, brain and other parts of central nervous system

  • C69 Malignant neoplasm of eye and adnexa
  • C70 Malignant neoplasm of meninges
  • C71 Malignant neoplasm of brain
  • C72 Malignant neoplasm of spinal cord, crani...
ICD-10-CM Range C73-C75

Malignant neoplasms of thyroid and other endocrine glands

  • C73 Malignant neoplasm of thyroid gland
  • C74 Malignant neoplasm of adrenal gland
  • C75 Malignant neoplasm of other endocrine gl...
ICD-10-CM Range C76-C80

Malignant neoplasms of ill-defined, other secondary and unspecified sites

  • C76 Malignant neoplasm of other and ill-defi...
  • C77 Secondary and unspecified malignant neop...
  • C78 Secondary malignant neoplasm of respirat...
  • C79 Secondary malignant neoplasm of other an...
  • C80 Malignant neoplasm without specification...
ICD-10-CM Range C7A-C7A

Malignant neuroendocrine tumors

  • C7A Malignant neuroendocrine tumors
ICD-10-CM Range C7B-C7B

Secondary neuroendocrine tumors

  • C7B Secondary neuroendocrine tumors
ICD-10-CM Range C81-C96

Malignant neoplasms of lymphoid, hematopoietic and related tissue

Type 2 Excludes
  • Kaposi's sarcoma of lymph nodes (C46.3)
  • secondary and unspecified neoplasm of lymph nodes (C77.-)
  • secondary neoplasm of bone marrow (C79.52)
  • secondary neoplasm of spleen (C78.89)
  • C81 Hodgkin lymphoma
  • C82 Follicular lymphoma
  • C83 Non-follicular lymphoma
  • C84 Mature T/NK-cell lymphomas
  • C85 Other specified and unspecified types of...
  • C86 Other specified types of T/NK-cell lymph...
  • C88 Malignant immunoproliferative diseases a...
  • C90 Multiple myeloma and malignant plasma ce...
  • C91 Lymphoid leukemia
  • C92 Myeloid leukemia
  • C93 Monocytic leukemia
  • C94 Other leukemias of specified cell type
  • C95 Leukemia of unspecified cell type
  • C96 Other and unspecified malignant neoplasm...
ICD-10-CM Range D00-D09

In situ neoplasms

Includes
  • Bowen's disease
  • erythroplasia
  • grade III intraepithelial neoplasia
  • Queyrat's erythroplasia
  • D00 Carcinoma in situ of oral cavity, esopha...
  • D01 Carcinoma in situ of other and unspecifi...
  • D02 Carcinoma in situ of middle ear and resp...
  • D03 Melanoma in situ
  • D04 Carcinoma in situ of skin
  • D05 Carcinoma in situ of breast
  • D06 Carcinoma in situ of cervix uteri
  • D07 Carcinoma in situ of other and unspecifi...
  • D09 Carcinoma in situ of other and unspecifi...
ICD-10-CM Range D10-D36

Benign neoplasms, except benign neuroendocrine tumors

  • D10 Benign neoplasm of mouth and pharynx
  • D11 Benign neoplasm of major salivary glands
  • D12 Benign neoplasm of colon, rectum, anus a...
  • D13 Benign neoplasm of other and ill-defined...
  • D14 Benign neoplasm of middle ear and respir...
  • D15 Benign neoplasm of other and unspecified...
  • D16 Benign neoplasm of bone and articular ca...
  • D17 Benign lipomatous neoplasm
  • D18 Hemangioma and lymphangioma, any site
  • D19 Benign neoplasm of mesothelial tissue
  • D20 Benign neoplasm of soft tissue of retrop...
  • D21 Other benign neoplasms of connective and...
  • D22 Melanocytic nevi
  • D23 Other benign neoplasms of skin
  • D24 Benign neoplasm of breast
  • D25 Leiomyoma of uterus
  • D26 Other benign neoplasms of uterus
  • D27 Benign neoplasm of ovary
  • D28 Benign neoplasm of other and unspecified...
  • D29 Benign neoplasm of male genital organs
  • D30 Benign neoplasm of urinary organs
  • D31 Benign neoplasm of eye and adnexa
  • D32 Benign neoplasm of meninges
  • D33 Benign neoplasm of brain and other parts...
  • D34 Benign neoplasm of thyroid gland
  • D35 Benign neoplasm of other and unspecified...
  • D36 Benign neoplasm of other and unspecified...
ICD-10-CM Range D37-D48

Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes

Note
  • Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made.
Type 1 Excludes
  • neoplasms of unspecified behavior (D49.-)
  • D37 Neoplasm of uncertain behavior of oral c...
  • D38 Neoplasm of uncertain behavior of middle...
  • D39 Neoplasm of uncertain behavior of female...
  • D40 Neoplasm of uncertain behavior of male g...
  • D41 Neoplasm of uncertain behavior of urinar...
  • D42 Neoplasm of uncertain behavior of mening...
  • D43 Neoplasm of uncertain behavior of brain ...
  • D44 Neoplasm of uncertain behavior of endocr...
  • D45 Polycythemia vera
  • D46 Myelodysplastic syndromes
  • D47 Other neoplasms of uncertain behavior of...
  • D48 Neoplasm of uncertain behavior of other ...
ICD-10-CM Range D3A-D3A

Benign neuroendocrine tumors

  • D3A Benign neuroendocrine tumors
ICD-10-CM Range D49-D49

Neoplasms of unspecified behavior

  • D49 Neoplasms of unspecified behavior