2017/18 ICD-10-CM Diagnosis Code C49

Malignant neoplasm of other connective and soft tissue

Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as C49. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • malignant neoplasm of cartilage (of):
  • articular (C40-C41
    ICD-10-CM Range C40-C41

    Malignant neoplasms of bone and articular cartilage

    Includes
    • malignant neoplasm of cartilage (articular) (joint)
    • malignant neoplasm of periosteum
    Type 1 Excludes
    • malignant neoplasm of bone marrow NOS (C96.9)
    • malignant neoplasm of synovia (C49.-)
    • C40 Malignant neoplasm of bone and articular...
    • C41 Malignant neoplasm of bone and articular...
    )
  • larynx (
    ICD-10-CM Diagnosis Code C32.3

    Malignant neoplasm of laryngeal cartilage

      2016 2017 2018 Billable/Specific Code
    C32.3
    )
  • nose (
    ICD-10-CM Diagnosis Code C30.0

    Malignant neoplasm of nasal cavity

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Malignant neoplasm of cartilage of nose
    • Malignant neoplasm of nasal concha
    • Malignant neoplasm of internal nose
    • Malignant neoplasm of septum of nose
    • Malignant neoplasm of vestibule of nose
    Type 1 Excludes
    • malignant neoplasm of nasal bone (C41.0)
    • malignant neoplasm of nose NOS (C76.0)
    • malignant neoplasm of olfactory bulb (C72.2-)
    • malignant neoplasm of posterior margin of nasal septum and choana (C11.3)
    • malignant melanoma of skin of nose (C43.31)
    • malignant neoplasm of turbinates (C41.0)
    • other and unspecified malignant neoplasm of skin of nose C44.301, C44.311, C44.321, C44.391)
    C30.0
    )
  • malignant neoplasm of connective tissue of breast (
    ICD-10-CM Diagnosis Code C50
    • C50 Malignant neoplasm of breast
      • C50.0 Malignant neoplasm of nipple and areola
        • C50.01 Malignant neoplasm of nipple and areola, fema...
          • C50.011 Malignant neoplasm of nipple and areola, righ...
          • C50.012 Malignant neoplasm of nipple and areola, left...
          • C50.019 Malignant neoplasm of nipple and areola, unsp...
        • C50.02 Malignant neoplasm of nipple and areola, male...
          • C50.021 Malignant neoplasm of nipple and areola, righ...
          • C50.022 Malignant neoplasm of nipple and areola, left...
          • C50.029 Malignant neoplasm of nipple and areola, unsp...
      • C50.1 Malignant neoplasm of central portion of brea...
        • C50.11 Malignant neoplasm of central portion of brea...
          • C50.111 Malignant neoplasm of central portion of righ...
          • C50.112 Malignant neoplasm of central portion of left...
          • C50.119 Malignant neoplasm of central portion of unsp...
        • C50.12 Malignant neoplasm of central portion of brea...
          • C50.121 Malignant neoplasm of central portion of righ...
          • C50.122 Malignant neoplasm of central portion of left...
          • C50.129 Malignant neoplasm of central portion of unsp...
      • C50.2 Malignant neoplasm of upper-inner quadrant of...
        • C50.21 Malignant neoplasm of upper-inner quadrant of...
          • C50.211 Malignant neoplasm of upper-inner quadrant of...
          • C50.212 Malignant neoplasm of upper-inner quadrant of...
          • C50.219 Malignant neoplasm of upper-inner quadrant of...
        • C50.22 Malignant neoplasm of upper-inner quadrant of...
          • C50.221 Malignant neoplasm of upper-inner quadrant of...
          • C50.222 Malignant neoplasm of upper-inner quadrant of...
          • C50.229 Malignant neoplasm of upper-inner quadrant of...
      • C50.3 Malignant neoplasm of lower-inner quadrant of...
        • C50.31 Malignant neoplasm of lower-inner quadrant of...
          • C50.311 Malignant neoplasm of lower-inner quadrant of...
          • C50.312 Malignant neoplasm of lower-inner quadrant of...
          • C50.319 Malignant neoplasm of lower-inner quadrant of...
        • C50.32 Malignant neoplasm of lower-inner quadrant of...
          • C50.321 Malignant neoplasm of lower-inner quadrant of...
          • C50.322 Malignant neoplasm of lower-inner quadrant of...
          • C50.329 Malignant neoplasm of lower-inner quadrant of...
      • C50.4 Malignant neoplasm of upper-outer quadrant of...
        • C50.41 Malignant neoplasm of upper-outer quadrant of...
          • C50.411 Malignant neoplasm of upper-outer quadrant of...
          • C50.412 Malignant neoplasm of upper-outer quadrant of...
          • C50.419 Malignant neoplasm of upper-outer quadrant of...
        • C50.42 Malignant neoplasm of upper-outer quadrant of...
          • C50.421 Malignant neoplasm of upper-outer quadrant of...
          • C50.422 Malignant neoplasm of upper-outer quadrant of...
          • C50.429 Malignant neoplasm of upper-outer quadrant of...
      • C50.5 Malignant neoplasm of lower-outer quadrant of...
        • C50.51 Malignant neoplasm of lower-outer quadrant of...
          • C50.511 Malignant neoplasm of lower-outer quadrant of...
          • C50.512 Malignant neoplasm of lower-outer quadrant of...
          • C50.519 Malignant neoplasm of lower-outer quadrant of...
        • C50.52 Malignant neoplasm of lower-outer quadrant of...
          • C50.521 Malignant neoplasm of lower-outer quadrant of...
          • C50.522 Malignant neoplasm of lower-outer quadrant of...
          • C50.529 Malignant neoplasm of lower-outer quadrant of...
      • C50.6 Malignant neoplasm of axillary tail of breast...
        • C50.61 Malignant neoplasm of axillary tail of breast...
          • C50.611 Malignant neoplasm of axillary tail of right ...
          • C50.612 Malignant neoplasm of axillary tail of left f...
          • C50.619 Malignant neoplasm of axillary tail of unspec...
        • C50.62 Malignant neoplasm of axillary tail of breast...
          • C50.621 Malignant neoplasm of axillary tail of right ...
          • C50.622 Malignant neoplasm of axillary tail of left m...
          • C50.629 Malignant neoplasm of axillary tail of unspec...
      • C50.8 Malignant neoplasm of overlapping sites of br...
        • C50.81 Malignant neoplasm of overlapping sites of br...
          • C50.811 Malignant neoplasm of overlapping sites of ri...
          • C50.812 Malignant neoplasm of overlapping sites of le...
          • C50.819 Malignant neoplasm of overlapping sites of un...
        • C50.82 Malignant neoplasm of overlapping sites of br...
          • C50.821 Malignant neoplasm of overlapping sites of ri...
          • C50.822 Malignant neoplasm of overlapping sites of le...
          • C50.829 Malignant neoplasm of overlapping sites of un...
      • C50.9 Malignant neoplasm of breast of unspecified s...
        • C50.91 Malignant neoplasm of breast of unspecified s...
          • C50.911 Malignant neoplasm of unspecified site of rig...
          • C50.912 Malignant neoplasm of unspecified site of lef...
          • C50.919 Malignant neoplasm of unspecified site of uns...
        • C50.92 Malignant neoplasm of breast of unspecified s...
          • C50.921 Malignant neoplasm of unspecified site of rig...
          • C50.922 Malignant neoplasm of unspecified site of lef...
          • C50.929 Malignant neoplasm of unspecified site of uns...
    C50.-
    )
Type 2 Excludes
Type 2 Excludes Help
A type 2 excludes note represents "not included here". A type 2 excludes note indicates that the condition excluded is not part of the condition it is excluded from but a patient may have both conditions at the same time. When a type 2 excludes note appears under a code it is acceptable to use both the code (C49) and the excluded code together.
  • Kaposi's sarcoma of soft tissue (
    ICD-10-CM Diagnosis Code C46.1

    Kaposi's sarcoma of soft tissue

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Kaposi's sarcoma of blood vessel
    • Kaposi's sarcoma of connective tissue
    • Kaposi's sarcoma of fascia
    • Kaposi's sarcoma of ligament
    • Kaposi's sarcoma of lymphatic(s) NEC
    • Kaposi's sarcoma of muscle
    Type 2 Excludes
    • Kaposi's sarcoma of lymph glands and nodes (C46.3)
    C46.1
    )
  • malignant neoplasm of heart (
    ICD-10-CM Diagnosis Code C38.0

    Malignant neoplasm of heart

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Malignant neoplasm of pericardium
    Type 1 Excludes
    • malignant neoplasm of great vessels (C49.3)
    C38.0
    )
  • malignant neoplasm of peripheral nerves and autonomic nervous system (
    ICD-10-CM Diagnosis Code C47
    • C47 Malignant neoplasm of peripheral nerves and a...
      • C47.0 Malignant neoplasm of peripheral nerves of he...
      • C47.1 Malignant neoplasm of peripheral nerves of up...
        • C47.10 Malignant neoplasm of peripheral nerves of un...
        • C47.11 Malignant neoplasm of peripheral nerves of ri...
        • C47.12 Malignant neoplasm of peripheral nerves of le...
      • C47.2 Malignant neoplasm of peripheral nerves of lo...
        • C47.20 Malignant neoplasm of peripheral nerves of un...
        • C47.21 Malignant neoplasm of peripheral nerves of ri...
        • C47.22 Malignant neoplasm of peripheral nerves of le...
      • C47.3 Malignant neoplasm of peripheral nerves of th...
      • C47.4 Malignant neoplasm of peripheral nerves of ab...
      • C47.5 Malignant neoplasm of peripheral nerves of pe...
      • C47.6 Malignant neoplasm of peripheral nerves of tr...
      • C47.8 Malignant neoplasm of overlapping sites of pe...
      • C47.9 Malignant neoplasm of peripheral nerves and a...
    C47.-
    )
  • malignant neoplasm of peritoneum (
    ICD-10-CM Diagnosis Code C48.2

    Malignant neoplasm of peritoneum, unspecified

      2016 2017 2018 Billable/Specific Code
    C48.2
    )
  • malignant neoplasm of retroperitoneum (
    ICD-10-CM Diagnosis Code C48.0

    Malignant neoplasm of retroperitoneum

      2016 2017 2018 Billable/Specific Code
    C48.0
    )
  • malignant neoplasm of uterine ligament (
    ICD-10-CM Diagnosis Code C57.3

    Malignant neoplasm of parametrium

      2016 2017 2018 Billable/Specific Code Female Dx
    Applicable To
    • Malignant neoplasm of uterine ligament NOS
    C57.3
    )
  • mesothelioma (
    ICD-10-CM Diagnosis Code C45
    • C45 Mesothelioma
      • C45.0 Mesothelioma of pleura
      • C45.1 Mesothelioma of peritoneum
      • C45.2 Mesothelioma of pericardium
      • C45.7 Mesothelioma of other sites
      • C45.9 Mesothelioma, unspecified
    C45.-
    )
Includes
Includes Help
"Includes" further defines, or give examples of, the content of the code or category.
  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia
  • malignant neoplasm of fat
  • malignant neoplasm of ligament, except uterine
  • malignant neoplasm of lymphatic vessel
  • malignant neoplasm of muscle
  • malignant neoplasm of synovia
  • malignant neoplasm of tendon (sheath)
The following code(s) above C49 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C49:
  • C00-D49
    2018 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
Clinical Information Code History
Code annotations containing back-references to C49:
ICD-10-CM Codes Adjacent To C49
C47.4 Malignant neoplasm of peripheral nerves of abdomen
C47.5 Malignant neoplasm of peripheral nerves of pelvis
C47.6 Malignant neoplasm of peripheral nerves of trunk, unspecified
C47.8 Malignant neoplasm of overlapping sites of peripheral nerves and autonomic nervous system
C47.9 Malignant neoplasm of peripheral nerves and autonomic nervous system, unspecified
C48 Malignant neoplasm of retroperitoneum and peritoneum
C48.0 Malignant neoplasm of retroperitoneum
C48.1 Malignant neoplasm of specified parts of peritoneum
C48.2 Malignant neoplasm of peritoneum, unspecified
C48.8 Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum
C49 Malignant neoplasm of other connective and soft tissue
C49.0 Malignant neoplasm of connective and soft tissue of head, face and neck
C49.1 Malignant neoplasm of connective and soft tissue of upper limb, including shoulder
C49.10 Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder
C49.11 Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder
C49.12 Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder
C49.2 Malignant neoplasm of connective and soft tissue of lower limb, including hip
C49.20 Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip
C49.21 Malignant neoplasm of connective and soft tissue of right lower limb, including hip
C49.22 Malignant neoplasm of connective and soft tissue of left lower limb, including hip
C49.3 Malignant neoplasm of connective and soft tissue of thorax

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.