2021 ICD-10-CM Diagnosis Code C81

Hodgkin lymphoma

    2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
  • C81 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2021 edition of ICD-10-CM C81 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of C81 - other international versions of ICD-10 C81 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as C81. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • personal history of Hodgkin lymphoma (
    ICD-10-CM Diagnosis Code Z85.71

    Personal history of Hodgkin lymphoma

      2016 2017 2018 2019 2020 2021 Billable/Specific Code POA Exempt
    Applicable To
    • Conditions classifiable to C81
    Z85.71
    )
The following code(s) above C81 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C81:
  • C00-D49
    2021 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C81-C96
    2021 ICD-10-CM Range C81-C96

    Malignant neoplasms of lymphoid, hematopoietic and related tissue

    Type 2 Excludes
    • Kaposi's sarcoma of lymph nodes (C46.3)
    • secondary and unspecified neoplasm of lymph nodes (C77.-)
    • secondary neoplasm of bone marrow (C79.52)
    • secondary neoplasm of spleen (C78.89)
    Malignant neoplasms of lymphoid, hematopoietic and related tissue
Clinical Information
  • A cancer of the immune system that is marked by the presence of a type of cell called the reed-sternberg cell. The two major types of hodgkin lymphoma are classical hodgkin lymphoma and nodular lymphocyte-predominant hodgkin lymphoma. Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats.
  • A lymphoma, previously known as hodgkin's disease, characterized by the presence of reed-sternberg cells. There are two distinct subtypes: nodular lymphocyte predominant hodgkin lymphoma and classical hodgkin lymphoma. Hodgkin lymphoma has a bimodal age distribution, and involves primarily lymph nodes. Current therapy for hodgkin lymphoma has resulted in an excellent outcome and cure for the majority of patients.
  • A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate hodgkin's and reed-sternberg cells are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
  • An obsolete term referring to hodgkin lymphoma.
  • Hodgkin disease is a type of lymphoma. lymphoma is cancer of lymph tissue found in the lymph nodes, spleen, liver, and bone marrow. The first sign of hodgkin disease is often an enlarged lymph node. The disease can spread to nearby lymph nodes. Later it may spread to the lungs, liver or bone marrow. The cause is unknown. Hodgkin disease is rare. Symptoms include
    • painless swelling of the lymph nodes in the neck, armpits, or groin
    • fever and chills
    • night sweats
    • weight loss
    • loss of appetite
    • itchy skin
    doctors can diagnose hodgkin disease with a biopsy. This involves removing and examining a piece of tissue under a microscope. Treatment varies depending on how far the disease has spread and often includes radiation therapy or chemotherapy. The earlier the disease is diagnosed, the more effective the treatment. In most cases, hodgkin disease can be cured. nih: national cancer institute
  • Malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue, and the presence of large, usually multinucleate, cells (reed-sternberg cells) of unknown origin.
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to C81:
  • Type 1 Excludes: C26.1
    ICD-10-CM Diagnosis Code C26.1

    Malignant neoplasm of spleen

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Type 1 Excludes
  • Applicable To: Z85.71
    ICD-10-CM Diagnosis Code Z85.71

    Personal history of Hodgkin lymphoma

      2016 2017 2018 2019 2020 2021 Billable/Specific Code POA Exempt
    Applicable To
    • Conditions classifiable to C81
ICD-10-CM Codes Adjacent To C81
C79.72 Secondary malignant neoplasm of left adrenal gland
C79.8 Secondary malignant neoplasm of other specified sites
C79.81 Secondary malignant neoplasm of breast
C79.82 Secondary malignant neoplasm of genital organs
C79.89 Secondary malignant neoplasm of other specified sites
C79.9 Secondary malignant neoplasm of unspecified site
C80 Malignant neoplasm without specification of site
C80.0 Disseminated malignant neoplasm, unspecified
C80.1 Malignant (primary) neoplasm, unspecified
C80.2 Malignant neoplasm associated with transplanted organ
C81 Hodgkin lymphoma
C81.0 Nodular lymphocyte predominant Hodgkin lymphoma
C81.00 …… unspecified site
C81.01 …… lymph nodes of head, face, and neck
C81.02 …… intrathoracic lymph nodes
C81.03 …… intra-abdominal lymph nodes
C81.04 …… lymph nodes of axilla and upper limb
C81.05 …… lymph nodes of inguinal region and lower limb
C81.06 …… intrapelvic lymph nodes
C81.07 …… spleen
C81.08 …… lymph nodes of multiple sites

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.