ICD-10-CM Codes
C00-D49 Neoplasms
D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
D47- Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

2017/18 ICD-10-CM Diagnosis Code D47.4

Osteomyelofibrosis

2016

2017

2018

Billable/Specific Code

D47.4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
The 2018 edition of ICD-10-CM D47.4 became effective on October 1, 2017.
This is the American ICD-10-CM version of D47.4 - other international versions of ICD-10 D47.4 may differ.

Applicable To

Chronic idiopathic myelofibrosis
Myelofibrosis (idiopathic) (with myeloid metaplasia)
Myelosclerosis (megakaryocytic) with myeloid metaplasia
Secondary myelofibrosis in myeloproliferative disease

Type 1 Excludes

Type 1 Excludes Help

A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D47.4. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

acute myelofibrosis (
ICD-10-CM Diagnosis Code C94.4
Acute panmyelosis with myelofibrosis
Applicable To
- Acute myelofibrosis
Type 1 Excludes
- myelofibrosis NOS (D75.81)
- secondary myelofibrosis NOS (D75.81)
C94.4-
)

The following code(s) above D47.4 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to D47.4:

C00-D49
2018 ICD-10-CM Range C00-D49
Neoplasms
Note
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
Neoplasms
D37-D48
2018 ICD-10-CM Range D37-D48
Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
Note
- Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made.
Type 1 Excludes
- neoplasms of unspecified behavior (D49.-)
Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes

Approximate Synonyms

Myelofibrosis with myeloid metaplasia
Myelosclerosis with myeloid metaplasia

Clinical Information

A chronic myeloproliferative neoplasm characterized by bone marrow fibrosis, proliferation of atypical megakaryocytes and granulocytes in the bone marrow, anemia, splenomegaly, and extramedullary hematopoiesis. The cause is unknown. The median survival time is 3-5 years from diagnosis. (who, 2001)
A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by cytokines arising from the abnormal clone.
A progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in organs such as the liver and the spleen, instead of in the bone marrow. This disease is marked by an enlarged spleen and progressive anemia.

ICD-10-CM D47.4 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0):

814 Reticuloendothelial and immunity disorders with mcc
815 Reticuloendothelial and immunity disorders with cc
816 Reticuloendothelial and immunity disorders without cc/mcc

Convert D47.4 to ICD-9-CM

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change

Code annotations containing back-references to D47.4:

Type 1 Excludes: D61.82
, D75.81

ICD-10-CM Diagnosis Code D61.82
Myelophthisis
Applicable To
- Leukoerythroblastic anemia
- Myelophthisic anemia
- Panmyelophthisis
Code Also
- the underlying disorder, such as:
- malignant neoplasm of breast (C50.-)
- tuberculosis (A15.-)
Type 1 Excludes
- idiopathic myelofibrosis (D47.1)
- myelofibrosis NOS (D75.81)
- myelofibrosis with myeloid metaplasia (D47.4)
- primary myelofibrosis (D47.1)
- secondary myelofibrosis (D75.81)
ICD-10-CM Diagnosis Code D75.81
Myelofibrosis
Applicable To
- Myelofibrosis NOS
- Secondary myelofibrosis NOS
Code First
- the underlying disorder, such as:
- malignant neoplasm of breast (C50.-)
Type 1 Excludes
- acute myelofibrosis (C94.4-)
- idiopathic myelofibrosis (D47.1)
- leukoerythroblastic anemia (D61.82)
- myelofibrosis with myeloid metaplasia (D47.4)
- myelophthisic anemia (D61.82)
- myelophthisis (D61.82)
- primary myelofibrosis (D47.1)
Use Additional
- code, if applicable, for associated therapy-related myelodysplastic syndrome (D46.-)

Diagnosis Index entries containing back-references to D47.4:

Myelofibrosis D75.81
ICD-10-CM Diagnosis Code D75.81
Myelofibrosis
Applicable To
Myelofibrosis NOS
Secondary myelofibrosis NOS
Code First
the underlying disorder, such as:
malignant neoplasm of breast (C50.-)
Type 1 Excludes
acute myelofibrosis (C94.4-)
idiopathic myelofibrosis (D47.1)
leukoerythroblastic anemia (D61.82)
myelofibrosis with myeloid metaplasia (D47.4)
myelophthisic anemia (D61.82)
myelophthisis (D61.82)
primary myelofibrosis (D47.1)
Use Additional
code, if applicable, for associated therapy-related myelodysplastic syndrome (D46.-)
- secondary D75.81
  ICD-10-CM Diagnosis Code D75.81
  Myelofibrosis
  2016 2017 2018 Billable/Specific Code Manifestation Code
  Applicable To
  Myelofibrosis NOS
  Secondary myelofibrosis NOS
  Code First
  the underlying disorder, such as:
  malignant neoplasm of breast (C50.-)
  Type 1 Excludes
  acute myelofibrosis (C94.4-)
  idiopathic myelofibrosis (D47.1)
  leukoerythroblastic anemia (D61.82)
  myelofibrosis with myeloid metaplasia (D47.4)
  myelophthisic anemia (D61.82)
  myelophthisis (D61.82)
  primary myelofibrosis (D47.1)
  Use Additional
  code, if applicable, for associated therapy-related myelodysplastic syndrome (D46.-)
  - in myeloproliferative disease D47.4
- with myeloid metaplasia D47.4
- idiopathic D47.4 (chronic)
Myelosclerosis D75.89
ICD-10-CM Diagnosis Code D75.89
Other specified diseases of blood and blood-forming organs
- megakaryocytic D47.4
  - with myeloid metaplasia D47.4
- with myeloid metaplasia D47.4
Osteomyelofibrosis D47.4

ICD-10-CM Codes Adjacent To D47.4

D46.Z Other myelodysplastic syndromes

D46.9 Myelodysplastic syndrome, unspecified

D47 Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

D47.0 Mast cell neoplasms of uncertain behavior

D47.01 Cutaneous mastocytosis

D47.02 Systemic mastocytosis

D47.09 Other mast cell neoplasms of uncertain behavior

D47.1 Chronic myeloproliferative disease

D47.2 Monoclonal gammopathy

D47.3 Essential (hemorrhagic) thrombocythemia

D47.4 Osteomyelofibrosis

D47.Z Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

D47.Z1 Post-transplant lymphoproliferative disorder (PTLD)

D47.Z2 Castleman disease

D47.Z9 Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

D47.9 Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified

D48 Neoplasm of uncertain behavior of other and unspecified sites

D48.0 Neoplasm of uncertain behavior of bone and articular cartilage

D48.1 Neoplasm of uncertain behavior of connective and other soft tissue

D48.2 Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system

D48.3 Neoplasm of uncertain behavior of retroperitoneum

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2017/18 ICD-10-CM Diagnosis Code D47.4

Osteomyelofibrosis

Acute panmyelosis with myelofibrosis

Neoplasms

Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes

Myelophthisis

Myelofibrosis

Myelofibrosis

Myelofibrosis

Other specified diseases of blood and blood-forming organs