2017/18 ICD-10-CM Diagnosis Code D68.5

Primary thrombophilia

Applicable To
  • Primary hypercoagulable states
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D68.5. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • antiphospholipid syndrome (
    ICD-10-CM Diagnosis Code D68.61

    Antiphospholipid syndrome

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Anticardiolipin syndrome
    • Antiphospholipid antibody syndrome
    Type 1 Excludes
    • anti-phospholipid antibody, finding without diagnosis (R76.0)
    • anti-phospholipid antibody with hemorrhagic disorder (D68.312)
    • lupus anticoagulant syndrome (D68.62)
    D68.61
    )
  • lupus anticoagulant (
    ICD-10-CM Diagnosis Code D68.62

    Lupus anticoagulant syndrome

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Lupus anticoagulant
    • Presence of systemic lupus erythematosus [SLE] inhibitor
    Type 1 Excludes
    • anticardiolipin syndrome (D68.61)
    • antiphospholipid syndrome (D68.61)
    • lupus anticoagulant (LAC) finding without diagnosis (R76.0)
    • lupus anticoagulant (LAC) with hemorrhagic disorder (D68.312)
    D68.62
    )
  • secondary activated protein C resistance (
    ICD-10-CM Diagnosis Code D68.69

    Other thrombophilia

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Hypercoagulable states NEC
    • Secondary hypercoagulable state NOS
    D68.69
    )
  • secondary antiphospholipid antibody syndrome (
    ICD-10-CM Diagnosis Code D68.69

    Other thrombophilia

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Hypercoagulable states NEC
    • Secondary hypercoagulable state NOS
    D68.69
    )
  • secondary lupus anticoagulant with hypercoagulable state (
    ICD-10-CM Diagnosis Code D68.69

    Other thrombophilia

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Hypercoagulable states NEC
    • Secondary hypercoagulable state NOS
    D68.69
    )
  • secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (
    ICD-10-CM Diagnosis Code D68.69

    Other thrombophilia

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Hypercoagulable states NEC
    • Secondary hypercoagulable state NOS
    D68.69
    )
  • systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (
    ICD-10-CM Diagnosis Code R76.0

    Raised antibody titer

      2016 2017 2018 Billable/Specific Code
    Type 1 Excludes
    • isoimmunization in pregnancy (O36.0-O36.1)
    • isoimmunization affecting newborn (P55.-)
    R76.0
    )
  • systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder (
    ICD-10-CM Diagnosis Code D68.312

    Antiphospholipid antibody with hemorrhagic disorder

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Lupus anticoagulant (LAC) with hemorrhagic disorder
    • Systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder
    Type 1 Excludes
    • antiphospholipid antibody, finding without diagnosis (R76.0)
    • antiphospholipid antibody syndrome (D68.61)
    • antiphospholipid antibody with hypercoagulable state (D68.61)
    • lupus anticoagulant (LAC) finding without diagnosis (R76.0)
    • lupus anticoagulant (LAC) with hypercoagulable state (D68.62)
    • systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
    • systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.62)
    D68.312
    )
  • thrombotic thrombocytopenic purpura (
    ICD-10-CM Diagnosis Code M31.1

    Thrombotic microangiopathy

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Thrombotic thrombocytopenic purpura
    M31.1
    )
The following code(s) above D68.5 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D68.5:
  • D50-D89
    2018 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D68
    ICD-10-CM Diagnosis Code D68

    Other coagulation defects

      2016 2017 2018 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • abnormal coagulation profile (R79.1)
    • coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1)
    • coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)
    Other coagulation defects
Code History
ICD-10-CM Codes Adjacent To D68.5
D68.0 Von Willebrand's disease
D68.1 Hereditary factor XI deficiency
D68.2 Hereditary deficiency of other clotting factors
D68.3 Hemorrhagic disorder due to circulating anticoagulants
D68.31 Hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors
D68.311 Acquired hemophilia
D68.312 Antiphospholipid antibody with hemorrhagic disorder
D68.318 Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors
D68.32 Hemorrhagic disorder due to extrinsic circulating anticoagulants
D68.4 Acquired coagulation factor deficiency
D68.5 Primary thrombophilia
D68.51 Activated protein C resistance
D68.52 Prothrombin gene mutation
D68.59 Other primary thrombophilia
D68.6 Other thrombophilia
D68.61 Antiphospholipid syndrome
D68.62 Lupus anticoagulant syndrome
D68.69 Other thrombophilia
D68.8 Other specified coagulation defects
D68.9 Coagulation defect, unspecified
D69 Purpura and other hemorrhagic conditions

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.