2021 ICD-10-CM Diagnosis Code D73.1

Hypersplenism

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • D73.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM D73.1 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of D73.1 - other international versions of ICD-10 D73.1 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D73.1. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • neutropenic splenomegaly (
    ICD-10-CM Diagnosis Code D73.81

    Neutropenic splenomegaly

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Werner-Schultz disease
    D73.81
    )
  • primary splenic neutropenia (
    ICD-10-CM Diagnosis Code D73.81

    Neutropenic splenomegaly

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Werner-Schultz disease
    D73.81
    )
  • splenitis, splenomegaly in late syphilis (
    ICD-10-CM Diagnosis Code A52.79

    Other symptomatic late syphilis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Late syphilitic leukoderma
    • Syphilis of adrenal gland
    • Syphilis of pituitary gland
    • Syphilis of thyroid gland
    • Syphilitic splenomegaly
    Type 1 Excludes
    • syphilitic leukoderma (secondary) (A51.39)
    A52.79
    )
  • splenitis, splenomegaly in tuberculosis (
    ICD-10-CM Diagnosis Code A18.85

    Tuberculosis of spleen

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    A18.85
    )
  • splenomegaly NOS (
    ICD-10-CM Diagnosis Code R16.1

    Splenomegaly, not elsewhere classified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Splenomegaly NOS
    R16.1
    )
  • splenomegaly congenital (
    ICD-10-CM Diagnosis Code Q89.0

    Congenital absence and malformations of spleen

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • isomerism of atrial appendages (with asplenia or polysplenia) (Q20.6)
    Q89.0
    )
The following code(s) above D73.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D73.1:
  • D50-D89
    2021 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Clinical Information
  • Condition characterized by splenomegaly, some reduction in the number of circulating blood cells in the presence of a normal or hyperactive bone marrow, and the potential for reversal by splenectomy.
ICD-10-CM D73.1 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 814 Reticuloendothelial and immunity disorders with mcc
  • 815 Reticuloendothelial and immunity disorders with cc
  • 816 Reticuloendothelial and immunity disorders without cc/mcc

Convert D73.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change

Diagnosis Index entries containing back-references to D73.1:
  • Aleukia
    • splenica D73.1
  • Big spleen syndrome D73.1
  • Gamna's disease D73.1 (siderotic splenomegaly)
  • Gandy-Nanta disease D73.1 (siderotic splenomegaly)
  • Hypersplenia, hypersplenism D73.1
  • Increase, increased
    • splenic activity D73.1
  • Metaplasia
    • myelogenous D73.1
    • myeloid D73.1 (agnogenic) (megakaryocytic)
    • spleen D73.1
  • Panhematopenia D61.9
    ICD-10-CM Diagnosis Code D61.9

    Aplastic anemia, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Hypoplastic anemia NOS
    • Medullary hypoplasia
    • splenic, primary D73.1
  • Syndrome - see also Disease
    • big spleen D73.1
    • hypersplenic D73.1

ICD-10-CM Codes Adjacent To D73.1
D72.822 Plasmacytosis
D72.823 Leukemoid reaction
D72.824 Basophilia
D72.825 Bandemia
D72.828 Other elevated white blood cell count
D72.829 …… unspecified
D72.89 Other specified disorders of white blood cells
D72.9 Disorder of white blood cells, unspecified
D73 Diseases of spleen
D73.0 Hyposplenism
D73.1 Hypersplenism
D73.2 Chronic congestive splenomegaly
D73.3 Abscess of spleen
D73.4 Cyst of spleen
D73.5 Infarction of spleen
D73.8 Other diseases of spleen
D73.81 Neutropenic splenomegaly
D73.89 Other diseases of spleen
D73.9 Disease of spleen, unspecified
D74 Methemoglobinemia
D74.0 Congenital methemoglobinemia

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.