Specific code icon 2017 ICD-10-CM Diagnosis Code E27.1

Primary adrenocortical insufficiency

    2016 2017 Billable/Specific Code

  • E27.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • This is the American ICD-10-CM version of E27.1. Other international versions of ICD-10 E27.1 may differ.
  • Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

Clinical Information
  • A hormonal disorder that occurs when the adrenal glands fail to release adequate amounts of glucocorticoids (cortisol), mineralocorticoids (aldosterone, 11-deoxycorticosterone), and androgens (dehydroepiandrosterone) to meet physiologic needs, despite release of acth from the pituitary.
  • A rare endocrine or hormonal disorder that occurs when the adrenal glands do not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal glands themselves (primary adrenal insufficiency) or to inadequate secretion of acth by the pituitary gland (secondary adrenal insufficiency).
  • An adrenal disease characterized by the progressive destruction of the adrenal cortex, resulting in insufficient production of aldosterone and hydrocortisone. Clinical symptoms include anorexia; nausea; weight loss; muscle weakness; and hyperpigmentation of the skin due to increase in circulating levels of acth precursor hormone which stimulates melanocytes.
  • Disease characterized by hypotension, weight loss, anorexia, weakness, and sometimes a bronze-like melanotic hyperpigmentation of the skin; due to tuberculosis or autoimmune induced disease (hypofunction) of the adrenal glands that results in deficiency of aldosterone and cortisol.
  • Your adrenal glands are just above your kidneys. The outside layer of these glands makes hormones that help your body respond to stress and regulate your blood pressure and water and salt balance. Addison's disease happens if the adrenal glands don't make enough of these hormones. A problem with your immune system usually causes addison's disease. The immune system mistakenly attacks your own tissues, damaging your adrenal glands. Other causes include infections and cancer. Symptoms include
    • weight loss
    • muscle weakness
    • fatigue that gets worse over time
    • low blood pressure
    • patchy or dark skin
    lab tests can confirm that you have addison's disease. If you don't treat it, it can be fatal. You will need to take hormone pills for the rest of your life. If you have addison's disease, you should carry an emergency id. It should say that you have the disease, list your medicines and say how much you need in an emergency.
Applicable To
  • Addison's disease
  • Autoimmune adrenalitis
Approximate Synonyms
  • Addison disease
  • Addison's disease, myopathy
  • Adrenal calcification
  • Adrenal insufficiency, primary
  • Myopathy due to Addison disease
  • Myopathy in Addison's disease
  • Primary adrenal insufficiency
Type 1 Excludes
  • Addison only phenotype adrenoleukodystrophy (E71.528)
  • amyloidosis (E85.-)
  • tuberculous Addison's disease (A18.7)
  • Waterhouse-Friderichsen syndrome (A39.1)
ICD-10-CM E27.1 is grouped within Diagnostic Related Group(s) (MS-DRG v34.0):
  • 643 Endocrine disorders with mcc
  • 644 Endocrine disorders with cc
  • 645 Endocrine disorders without cc/mcc

Convert ICD-10-CM E27.1 to ICD-9-CM

The following ICD-10-CM Index entries contain back-references to ICD-10-CM E27.1: