2017/18 ICD-10-CM Diagnosis Code E88.0

Disorders of plasma-protein metabolism, not elsewhere classified

Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as E88.0. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • disorder of lipoprotein metabolism (
    ICD-10-CM Diagnosis Code E78
    • E78 Disorders of lipoprotein metabolism and other...
      • E78.0 Pure hypercholesterolemia
        • E78.00 …… unspecified
        • E78.01 Familial hypercholesterolemia
      • E78.1 Pure hyperglyceridemia
      • E78.2 Mixed hyperlipidemia
      • E78.3 Hyperchylomicronemia
      • E78.4 Other hyperlipidemia
      • E78.5 Hyperlipidemia, unspecified
      • E78.6 Lipoprotein deficiency
      • E78.7 Disorders of bile acid and cholesterol metabo...
        • E78.70 Disorder of bile acid and cholesterol metabol...
        • E78.71 Barth syndrome
        • E78.72 Smith-Lemli-Opitz syndrome
        • E78.79 Other disorders of bile acid and cholesterol ...
      • E78.8 Other disorders of lipoprotein metabolism
        • E78.81 Lipoid dermatoarthritis
        • E78.89 Other lipoprotein metabolism disorders
      • E78.9 Disorder of lipoprotein metabolism, unspecifi...
    E78.-
    )
  • monoclonal gammopathy (of undetermined significance) (
    ICD-10-CM Diagnosis Code D47.2

    Monoclonal gammopathy

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Monoclonal gammopathy of undetermined significance [MGUS]
    D47.2
    )
  • polyclonal hypergammaglobulinemia (
    ICD-10-CM Diagnosis Code D89.0

    Polyclonal hypergammaglobulinemia

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Benign hypergammaglobulinemic purpura
    • Polyclonal gammopathy NOS
    D89.0
    )
  • Waldenström macroglobulinemia (
    ICD-10-CM Diagnosis Code C88.0

    Waldenström macroglobulinemia

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Lymphoplasmacytic lymphoma with IgM-production
    • Macroglobulinemia (idiopathic) (primary)
    Type 1 Excludes
    • small cell B-cell lymphoma (C83.0)
    C88.0
    )
The following code(s) above E88.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E88.0:
  • E00-E89
    2018 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E70-E88
    2018 ICD-10-CM Range E70-E88

    Metabolic disorders

    Type 1 Excludes
    • androgen insensitivity syndrome (E34.5-)
    • congenital adrenal hyperplasia (E25.0)
    • Ehlers-Danlos syndrome (Q79.6)
    • hemolytic anemias attributable to enzyme disorders (D55.-)
    • Marfan's syndrome (Q87.4)
    • 5-alpha-reductase deficiency (E29.1)
    Metabolic disorders
  • E88
    ICD-10-CM Diagnosis Code E88

    Other and unspecified metabolic disorders

      2016 2017 2018 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • histiocytosis X (chronic) (C96.6)
    Use Additional
    • codes for associated conditions
    Other and unspecified metabolic disorders
Code History
Code annotations containing back-references to E88.0:
ICD-10-CM Codes Adjacent To E88.0
E87.3 Alkalosis
E87.4 Mixed disorder of acid-base balance
E87.5 Hyperkalemia
E87.6 Hypokalemia
E87.7 Fluid overload
E87.70 …… unspecified
E87.71 Transfusion associated circulatory overload
E87.79 Other fluid overload
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
E88 Other and unspecified metabolic disorders
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
E88.01 Alpha-1-antitrypsin deficiency
E88.09 Other disorders of plasma-protein metabolism, not elsewhere classified
E88.1 Lipodystrophy, not elsewhere classified
E88.2 Lipomatosis, not elsewhere classified
E88.3 Tumor lysis syndrome
E88.4 Mitochondrial metabolism disorders
E88.40 Mitochondrial metabolism disorder, unspecified
E88.41 MELAS syndrome
E88.42 MERRF syndrome
E88.49 Other mitochondrial metabolism disorders

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.