2017/18 ICD-10-CM Diagnosis Code K52.21

Food protein-induced enterocolitis syndrome

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Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code for hypovolemic shock, if present (
    ICD-10-CM Diagnosis Code R57.1

    Hypovolemic shock

      2016 2017 2018 Billable/Specific Code
    R57.1
    )
The following code(s) above K52.21 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to K52.21:
  • K00-K95
    2018 ICD-10-CM Range K00-K95

    Diseases of the digestive system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the digestive system
  • K50-K52
    2018 ICD-10-CM Range K50-K52

    Noninfective enteritis and colitis

    Includes
    • noninfective inflammatory bowel disease
    Type 1 Excludes
    Noninfective enteritis and colitis
  • K52.2
    ICD-10-CM Diagnosis Code K52.2

    Allergic and dietetic gastroenteritis and colitis

      2016 2017 - Deleted Code 2017 - New Code 2018 Non-Billable/Non-Specific Code
    Applicable To
    • Food hypersensitivity gastroenteritis or colitis
    Type 2 Excludes
    • allergic eosinophilic colitis (K52.82)
    • allergic eosinophilic esophagitis (K20.0)
    • allergic eosinophilic gastritis (K52.81)
    • allergic eosinophilic gastroenteritis (K52.81)
    • food protein-induced proctocolitis (K52.82)
    Use Additional
    Allergic and dietetic gastroenteritis and colitis
ICD-10-CM K52.21 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0):

Convert K52.21 to ICD-9-CM

Code History
Code annotations containing back-references to K52.21:

Diagnosis Index entries containing back-references to K52.21:

ICD-10-CM Codes Adjacent To K52.21
K51.911 Ulcerative colitis, unspecified with rectal bleeding
K51.912 Ulcerative colitis, unspecified with intestinal obstruction
K51.913 Ulcerative colitis, unspecified with fistula
K51.914 Ulcerative colitis, unspecified with abscess
K51.918 Ulcerative colitis, unspecified with other complication
K51.919 Ulcerative colitis, unspecified with unspecified complications
K52 Other and unspecified noninfective gastroenteritis and colitis
K52.0 Gastroenteritis and colitis due to radiation
K52.1 Toxic gastroenteritis and colitis
K52.2 Allergic and dietetic gastroenteritis and colitis
K52.21 Food protein-induced enterocolitis syndrome
K52.22 Food protein-induced enteropathy
K52.29 Other allergic and dietetic gastroenteritis and colitis
K52.3 Indeterminate colitis
K52.8 Other specified noninfective gastroenteritis and colitis
K52.81 Eosinophilic gastritis or gastroenteritis
K52.82 Eosinophilic colitis
K52.83 Microscopic colitis
K52.831 Collagenous colitis
K52.832 Lymphocytic colitis
K52.838 Other microscopic colitis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.