2021 ICD-10-CM Diagnosis Code K72.0

Acute and subacute hepatic failure

    2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
  • K72.0 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2021 edition of ICD-10-CM K72.0 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of K72.0 - other international versions of ICD-10 K72.0 may differ.
Applicable To
  • Acute non-viral hepatitis NOS
The following code(s) above K72.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to K72.0:
  • K00-K95
    2021 ICD-10-CM Range K00-K95

    Diseases of the digestive system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the digestive system
  • K70-K77
    2021 ICD-10-CM Range K70-K77

    Diseases of liver

    Type 1 Excludes
    • jaundice NOS (R17)
    Type 2 Excludes
    Diseases of liver
  • K72
    ICD-10-CM Diagnosis Code K72

    Hepatic failure, not elsewhere classified

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Includes
    • fulminant hepatitis NEC, with hepatic failure
    • hepatic encephalopathy NOS
    • liver (cell) necrosis with hepatic failure
    • malignant hepatitis NEC, with hepatic failure
    • yellow liver atrophy or dystrophy
    Type 1 Excludes
    • alcoholic hepatic failure (K70.4)
    • hepatic failure with toxic liver disease (K71.1-)
    • icterus of newborn (P55-P59)
    • postprocedural hepatic failure (K91.82)
    Type 2 Excludes
    • hepatic failure complicating abortion or ectopic or molar pregnancy (O00-O07, O08.8)
    • hepatic failure complicating pregnancy, childbirth and the puerperium (O26.6-)
    • viral hepatitis with hepatic coma (B15-B19)
    Hepatic failure, not elsewhere classified
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to K72.0:
  • Code Also: M35.81
    ICD-10-CM Diagnosis Code M35.81

    Multisystem inflammatory syndrome

      2021 - New Code Billable/Specific Code
    Applicable To
    • MIS-A
    • MIS-C
    • Multisystem inflammatory syndrome in adults
    • Multisystem inflammatory syndrome in children
    • Pediatric inflammatory multisystem syndrome
    • PIMS
    Code First
    • , if applicable, COVID-19 (U07.1)
    Code Also
    • any associated complications such as:
    • acute hepatic failure (K72.0-)
    • acute kidney failure (N17.-)
    • acute myocarditis (I40.-)
    • acute respiratory distress syndrome (J80)
    • cardiac arrhythmia (I47-I49.-)
    • pneumonia due to COVID-19 (J12.82)
    • severe sepsis (R65.2-)
    • viral cardiomyopathy (B33.24)
    • viral pericarditis (B33.23)
    Use Additional
    • code, if applicable, for:
    • exposure to COVID-19 or SARS-CoV-2 infection (Z20.822)
    • personal history of COVID-19 (Z86.16)
    • sequelae of COVID-19 (B94.8)
  • Type 1 Excludes: K75.2
    , K75.3
    , K75.9
    ICD-10-CM Diagnosis Code K75.2

    Nonspecific reactive hepatitis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Type 1 Excludes
    • acute or subacute hepatitis (K72.0-)
    • chronic hepatitis NEC (K73.-)
    • viral hepatitis (B15-B19)
    ICD-10-CM Diagnosis Code K75.3

    Granulomatous hepatitis, not elsewhere classified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Type 1 Excludes
    • acute or subacute hepatitis (K72.0-)
    • chronic hepatitis NEC (K73.-)
    • viral hepatitis (B15-B19)
    ICD-10-CM Diagnosis Code K75.9

    Inflammatory liver disease, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Hepatitis NOS
    Type 1 Excludes
    • acute or subacute hepatitis (K72.0-)
    • chronic hepatitis NEC (K73.-)
    • viral hepatitis (B15-B19)
  • Type 2 Excludes: K75.0
    ICD-10-CM Diagnosis Code K75.0

    Abscess of liver

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Cholangitic hepatic abscess
    • Hematogenic hepatic abscess
    • Hepatic abscess NOS
    • Lymphogenic hepatic abscess
    • Pylephlebitic hepatic abscess
    Type 1 Excludes
    • amebic liver abscess (A06.4)
    • cholangitis without liver abscess (K83.09)
    • pylephlebitis without liver abscess (K75.1)
    Type 2 Excludes
    • acute or subacute hepatitis NOS (B17.9)
    • acute or subacute non-viral hepatitis (K72.0)
    • chronic hepatitis NEC (K73.8)
  • Use Additional: R65.11
    , R65.2
    ICD-10-CM Diagnosis Code R65.11

    Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Use Additional
    • code to identify specific acute organ dysfunction, such as:
    • acute kidney failure (N17.-)
    • acute respiratory failure (J96.0-)
    • critical illness myopathy (G72.81)
    • critical illness polyneuropathy (G62.81)
    • disseminated intravascular coagulopathy [DIC] (D65)
    • encephalopathy (metabolic) (septic) (G93.41)
    • hepatic failure (K72.0-)
    ICD-10-CM Diagnosis Code R65.2

    Severe sepsis

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Applicable To
    • Infection with associated acute organ dysfunction
    • Sepsis with acute organ dysfunction
    • Sepsis with multiple organ dysfunction
    • Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction
    Code First
    • underlying infection, such as:
    • infection following a procedure (T81.4-)
    • infections following infusion, transfusion and therapeutic injection (T80.2-)
    • puerperal sepsis (O85)
    • sepsis following complete or unspecified spontaneous abortion (O03.87)
    • sepsis following ectopic and molar pregnancy (O08.82)
    • sepsis following incomplete spontaneous abortion (O03.37)
    • sepsis following (induced) termination of pregnancy (O04.87)
    • sepsis NOS (A41.9)
    Use Additional
    • code to identify specific acute organ dysfunction, such as:
    • acute kidney failure (N17.-)
    • acute respiratory failure (J96.0-)
    • critical illness myopathy (G72.81)
    • critical illness polyneuropathy (G62.81)
    • disseminated intravascular coagulopathy [DIC] (D65)
    • encephalopathy (metabolic) (septic) (G93.41)
    • hepatic failure (K72.0-)

Diagnosis Index entries containing back-references to K72.0:
  • Hepatitis K75.9
    ICD-10-CM Diagnosis Code K75.9

    Inflammatory liver disease, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Hepatitis NOS
    Type 1 Excludes
    • acute or subacute hepatitis (K72.0-)
    • chronic hepatitis NEC (K73.-)
    • viral hepatitis (B15-B19)
    • acute B17.9
      ICD-10-CM Diagnosis Code B17.9

      Acute viral hepatitis, unspecified

        2016 2017 2018 2019 2020 2021 Billable/Specific Code
      Applicable To
      • Acute hepatitis NOS
      • Acute infectious hepatitis NOS
      • non-viral K72.0

ICD-10-CM Codes Adjacent To K72.0
K71.3 Toxic liver disease with chronic persistent hepatitis
K71.4 Toxic liver disease with chronic lobular hepatitis
K71.5 Toxic liver disease with chronic active hepatitis
K71.50 …… without ascites
K71.51 …… with ascites
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
K71.8 Toxic liver disease with other disorders of liver
K71.9 Toxic liver disease, unspecified
K72 Hepatic failure, not elsewhere classified
K72.0 Acute and subacute hepatic failure
K72.00 …… without coma
K72.01 …… with coma
K72.1 Chronic hepatic failure
K72.10 …… without coma
K72.11 …… with coma
K72.9 Hepatic failure, unspecified
K72.90 …… without coma
K72.91 …… with coma
K73 Chronic hepatitis, not elsewhere classified
K73.0 Chronic persistent hepatitis, not elsewhere classified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.