Specific code icon 2014 ICD-10-CM Diagnosis Code M35.1

Other overlap syndromes

  • M35.1 is a billable ICD-10-CM code that can be used to specify a diagnosis.
  • On October 1, 2015 ICD-10-CM will replace ICD-9-CM in the United States, therefore, M35.1 and all other ICD-10-CM codes should only be used for training or planning purposes until then.
Clinical Information
  • A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.
  • An autoimmune overlap syndrome characterized by the presence of symptoms of systemic lupus erythematosus, systemic scleroderma, and polymyositis.
Applicable To
  • Mixed connective tissue disease
Type 1 Excludes
  • polyangiitis overlap syndrome (M30.8)
Mortality Data
  • Between 1999-2007 there were 72 deaths in the United States where ICD-10 M35.1 was indicated as the underlying cause of death [source: cdc.govlink to cdc.gov]
  • ICD-10 M35.1 as underlying cause of death data broken down by: gender, age, race, year
ICD-10-CM M35.1 is grouped within Diagnostic Related Group(s) (MS-DRG v30.0):
  • 545 Connective tissue disorders with mcc
  • 546 Connective tissue disorders with cc
  • 547 Connective tissue disorders without cc/mcc
Convert ICD-10-CM M35.1 to ICD-9-CM
The following ICD-10-CM Index entries contain back-references to ICD-10-CM M35.1: