2017/18 ICD-10-CM Diagnosis Code N16

Renal tubulo-interstitial disorders in diseases classified elsewhere

ICD-10-CM Coding Rules
Applicable To
  • Pyelonephritis
  • Tubulo-interstitial nephritis
Code First
Code First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • underlying disease, such as:
  • brucellosis (
    ICD-10-CM Diagnosis Code A23.0

    Brucellosis due to Brucella melitensis

      2016 2017 2018 Billable/Specific Code
    A23.0-
    ICD-10-CM Diagnosis Code A23.9

    Brucellosis, unspecified

      2016 2017 2018 Billable/Specific Code
    A23.9
    )
  • cryoglobulinemia (
    ICD-10-CM Diagnosis Code D89.1

    Cryoglobulinemia

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Cryoglobulinemic purpura
    • Cryoglobulinemic vasculitis
    • Essential cryoglobulinemia
    • Idiopathic cryoglobulinemia
    • Mixed cryoglobulinemia
    • Primary cryoglobulinemia
    • Secondary cryoglobulinemia
    D89.1
    )
  • glycogen storage disease (
    ICD-10-CM Diagnosis Code E74.0

    Glycogen storage disease

      2016 2017 2018 Non-Billable/Non-Specific Code
    E74.0
    )
  • leukemia (
    ICD-10-CM Diagnosis Code C91

    Lymphoid leukemia

      2016 2017 2018 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • personal history of leukemia (Z85.6)
    C91
    -
    ICD-10-CM Diagnosis Code C95

    Leukemia of unspecified cell type

      2016 2017 2018 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • personal history of leukemia (Z85.6)
    C95
    )
  • lymphoma (
    ICD-10-CM Diagnosis Code C81.0

    Nodular lymphocyte predominant Hodgkin lymphoma

      2016 2017 2018 Non-Billable/Non-Specific Code
    C81.0-
    ICD-10-CM Diagnosis Code C85.9

    Non-Hodgkin lymphoma, unspecified

      2016 2017 2018 Non-Billable/Non-Specific Code
    Applicable To
    • Lymphoma NOS
    • Malignant lymphoma NOS
    • Non-Hodgkin lymphoma NOS
    C85.9
    ,
    ICD-10-CM Diagnosis Code C96.0

    Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Histiocytosis X, multisystemic
    • Letterer-Siwe disease
    Type 1 Excludes
    • adult pulmonary Langerhans cell histiocytosis (J84.82)
    • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
    • unifocal Langerhans-cell histiocytosis (C96.6)
    C96.0-
    ICD-10-CM Diagnosis Code C96.9

    Malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecified

      2016 2017 2018 Billable/Specific Code
    C96.9
    )
  • multiple myeloma (
    ICD-10-CM Diagnosis Code C90.0

    Multiple myeloma

      2016 2017 2018 Non-Billable/Non-Specific Code
    Applicable To
    • Kahler's disease
    • Medullary plasmacytoma
    • Myelomatosis
    • Plasma cell myeloma
    Type 1 Excludes
    C90.0-
    )
  • sepsis (
    ICD-10-CM Diagnosis Code A40.0

    Sepsis due to streptococcus, group A

      2016 2017 2018 Billable/Specific Code
    A40.0-
    ICD-10-CM Diagnosis Code A41.9

    Sepsis, unspecified organism

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Septicemia NOS
    A41.9
    )
  • Wilson's disease (
    ICD-10-CM Diagnosis Code E83.0

    Disorders of copper metabolism

      2016 2017 2018 Non-Billable/Non-Specific Code
    E83.0
    )
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as N16. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • diphtheritic pyelonephritis and tubulo-interstitial nephritis (
    ICD-10-CM Diagnosis Code A36.84

    Diphtheritic tubulo-interstitial nephropathy

      2016 2017 2018 Billable/Specific Code
    A36.84
    )
  • pyelonephritis and tubulo-interstitial nephritis in candidiasis (
    ICD-10-CM Diagnosis Code B37.49

    Other urogenital candidiasis

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Candidal pyelonephritis
    B37.49
    )
  • pyelonephritis and tubulo-interstitial nephritis in cystinosis (
    ICD-10-CM Diagnosis Code E72.04

    Cystinosis

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Fanconi (-de Toni) (-Debré) syndrome with cystinosis
    Type 1 Excludes
    • Fanconi (-de Toni) (-Debré) syndrome without cystinosis (E72.09)
    E72.04
    )
  • pyelonephritis and tubulo-interstitial nephritis in salmonella infection (
    ICD-10-CM Diagnosis Code A02.25

    Salmonella pyelonephritis

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Salmonella tubulo-interstitial nephropathy
    A02.25
    )
  • pyelonephritis and tubulo-interstitial nephritis in sarcoidosis (
    ICD-10-CM Diagnosis Code D86.84

    Sarcoid pyelonephritis

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Tubulo-interstitial nephropathy in sarcoidosis
    D86.84
    )
  • pyelonephritis and tubulo-interstitial nephritis in sicca syndrome [Sjogren's] (
    ICD-10-CM Diagnosis Code M35.04

    Sicca syndrome with tubulo-interstitial nephropathy

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Renal tubular acidosis in sicca syndrome
    M35.04
    )
  • pyelonephritis and tubulo-interstitial nephritis in systemic lupus erythematosus (
    ICD-10-CM Diagnosis Code M32.15

    Tubulo-interstitial nephropathy in systemic lupus erythematosus

      2016 2017 2018 Billable/Specific Code
    M32.15
    )
  • pyelonephritis and tubulo-interstitial nephritis in toxoplasmosis (
    ICD-10-CM Diagnosis Code B58.83

    Toxoplasma tubulo-interstitial nephropathy

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Toxoplasma pyelonephritis
    B58.83
    )
  • renal tubular degeneration in diabetes (E08-E13
    ICD-10-CM Range E08-E13

    Diabetes mellitus

    • E08 Diabetes mellitus due to underlying cond...
    • E09 Drug or chemical induced diabetes mellit...
    • E10 Type 1 diabetes mellitus
    • E11 Type 2 diabetes mellitus
    • E13 Other specified diabetes mellitus
    with .29)
  • syphilitic pyelonephritis and tubulo-interstitial nephritis (
    ICD-10-CM Diagnosis Code A52.75

    Syphilis of kidney and ureter

      2016 2017 2018 Billable/Specific Code
    Applicable To
    • Syphilitic glomerular disease
    A52.75
    )
The following code(s) above N16 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to N16:
  • N00-N99
    2018 ICD-10-CM Range N00-N99

    Diseases of the genitourinary system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the genitourinary system
  • N10-N16
    2018 ICD-10-CM Range N10-N16

    Renal tubulo-interstitial diseases

    Includes
    • pyelonephritis
    Type 1 Excludes
    • pyeloureteritis cystica (N28.85)
    Renal tubulo-interstitial diseases
Approximate Synonyms Clinical Information ICD-10-CM N16 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0):

Convert N16 to ICD-9-CM

Code History
Code annotations containing back-references to N16:
ICD-10-CM Codes Adjacent To N16
N14.0 Analgesic nephropathy
N14.1 Nephropathy induced by other drugs, medicaments and biological substances
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance
N14.3 Nephropathy induced by heavy metals
N14.4 Toxic nephropathy, not elsewhere classified
N15 Other renal tubulo-interstitial diseases
N15.0 Balkan nephropathy
N15.1 Renal and perinephric abscess
N15.8 Other specified renal tubulo-interstitial diseases
N15.9 Renal tubulo-interstitial disease, unspecified
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
N17 Acute kidney failure
N17.0 Acute kidney failure with tubular necrosis
N17.1 Acute kidney failure with acute cortical necrosis
N17.2 Acute kidney failure with medullary necrosis
N17.8 Other acute kidney failure
N17.9 Acute kidney failure, unspecified
N18 Chronic kidney disease (CKD)
N18.1 Chronic kidney disease, stage 1
N18.2 Chronic kidney disease, stage 2 (mild)
N18.3 Chronic kidney disease, stage 3 (moderate)

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.