2021 ICD-10-CM Diagnosis Code R78.81

Bacteremia

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • R78.81 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM R78.81 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of R78.81 - other international versions of ICD-10 R78.81 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as R78.81. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • sepsis-code to specified infection
The following code(s) above R78.81 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to R78.81:
  • R00-R99
    2021 ICD-10-CM Range R00-R99

    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

    Note
    • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
    • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
    • The conditions and signs or symptoms included in categories R00-R94 consist of:
    • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
    • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
    • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
    • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
    • (e) cases in which a more precise diagnosis was not available for any other reason;
    • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.
    Type 2 Excludes
    • abnormal findings on antenatal screening of mother (O28.-)
    • certain conditions originating in the perinatal period (P04-P96)
    • signs and symptoms classified in the body system chapters
    • signs and symptoms of breast (N63, N64.5)
    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
  • R70-R79
    2021 ICD-10-CM Range R70-R79

    Abnormal findings on examination of blood, without diagnosis

    Type 2 Excludes
    • abnormal findings on antenatal screening of mother (O28.-)
    • abnormalities of lipids (E78.-)
    • abnormalities of platelets and thrombocytes (D69.-)
    • abnormalities of white blood cells classified elsewhere (D70-D72)
    • coagulation hemorrhagic disorders (D65-D68)
    • diagnostic abnormal findings classified elsewhere - see Alphabetical Index
    • hemorrhagic and hematological disorders of newborn (P50-P61)
    Abnormal findings on examination of blood, without diagnosis
  • R78
    ICD-10-CM Diagnosis Code R78

    Findings of drugs and other substances, not normally found in blood

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • mental or behavioral disorders due to psychoactive substance use (F10-F19)
    Use Additional
    • code to identify the any retained foreign body, if applicable (Z18.-)
    Findings of drugs and other substances, not normally found in blood
Approximate Synonyms
  • Bacteremia (bacteria in blood)
  • Bacteremia caused by gram-negative bacteria
  • Bacteremia caused by gram-positive bacteria
  • Bacteremia due to gram negative bacteria
  • Bacteremia due to gram positive bacteria
  • Bacteremia due to salmonella
  • Bacteremia due to staphylococcus aureus
  • Gram negative bacteremia
  • Gram positive bacteremia
  • Salmonella bacteremia
  • Staph aureus bacteremia
Clinical Information
  • The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
ICD-10-CM R78.81 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 791 Prematurity with major problems
  • 793 Full term neonate with major problems
  • 870 Septicemia or severe sepsis with mv >96 hours
  • 871 Septicemia or severe sepsis without mv >96 hours with mcc
  • 872 Septicemia or severe sepsis without mv >96 hours without mcc

Convert R78.81 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to R78.81:
  • Type 1 Excludes: A41
    , A49.9
    ICD-10-CM Diagnosis Code A41

    Other sepsis

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Code First
    • postprocedural sepsis (T81.4-)
    • sepsis during labor (O75.3)
    • sepsis following abortion, ectopic or molar pregnancy (O03-O07, O08.0)
    • sepsis following immunization (T88.0)
    • sepsis following infusion, transfusion or therapeutic injection (T80.2-)
    Type 1 Excludes
    Type 2 Excludes
    • sepsis (due to) (in) actinomycotic (A42.7)
    • sepsis (due to) (in) anthrax (A22.7)
    • sepsis (due to) (in) candidal (B37.7)
    • sepsis (due to) (in) Erysipelothrix (A26.7)
    • sepsis (due to) (in) extraintestinal yersiniosis (A28.2)
    • sepsis (due to) (in) gonococcal (A54.86)
    • sepsis (due to) (in) herpesviral (B00.7)
    • sepsis (due to) (in) listerial (A32.7)
    • sepsis (due to) (in) melioidosis (A24.1)
    • sepsis (due to) (in) meningococcal (A39.2-A39.4)
    • sepsis (due to) (in) plague (A20.7)
    • sepsis (due to) (in) tularemia (A21.7)
    • toxic shock syndrome (A48.3)
    ICD-10-CM Diagnosis Code A49.9

    Bacterial infection, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Type 1 Excludes

Diagnosis Index entries containing back-references to R78.81:

ICD-10-CM Codes Adjacent To R78.81
R78.1 Finding of opiate drug in blood
R78.2 Finding of cocaine in blood
R78.3 Finding of hallucinogen in blood
R78.4 Finding of other drugs of addictive potential in blood
R78.5 Finding of other psychotropic drug in blood
R78.6 Finding of steroid agent in blood
R78.7 Finding of abnormal level of heavy metals in blood
R78.71 Abnormal lead level in blood
R78.79 Finding of abnormal level of heavy metals in blood
R78.8 Finding of other specified substances, not normally found in blood
R78.81 Bacteremia
R78.89 Finding of other specified substances, not normally found in blood
R78.9 Finding of unspecified substance, not normally found in blood
R79 Other abnormal findings of blood chemistry
R79.0 Abnormal level of blood mineral
R79.1 Abnormal coagulation profile
R79.8 Other specified abnormal findings of blood chemistry
R79.81 Abnormal blood-gas level
R79.82 Elevated C-reactive protein (CRP)
R79.89 Other specified abnormal findings of blood chemistry
R79.9 Abnormal finding of blood chemistry, unspecified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.