2017/18 ICD-10-CM Diagnosis Code Z15.0

Genetic susceptibility to malignant neoplasm

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Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code, if applicable, for any personal history of malignant neoplasm (
    ICD-10-CM Diagnosis Code Z85
    • Z85 Personal history of malignant neoplasm
      • Z85.0 Personal history of malignant neoplasm of dig...
        • Z85.00 Personal history of malignant neoplasm of uns...
        • Z85.01 Personal history of malignant neoplasm of eso...
        • Z85.02 Personal history of malignant neoplasm of sto...
          • Z85.020 Personal history of malignant carcinoid tumor...
          • Z85.028 Personal history of other malignant neoplasm ...
        • Z85.03 Personal history of malignant neoplasm of lar...
          • Z85.030 Personal history of malignant carcinoid tumor...
          • Z85.038 Personal history of other malignant neoplasm ...
        • Z85.04 Personal history of malignant neoplasm of rec...
          • Z85.040 Personal history of malignant carcinoid tumor...
          • Z85.048 Personal history of other malignant neoplasm ...
        • Z85.05 Personal history of malignant neoplasm of liv...
        • Z85.06 Personal history of malignant neoplasm of sma...
          • Z85.060 Personal history of malignant carcinoid tumor...
          • Z85.068 Personal history of other malignant neoplasm ...
        • Z85.07 Personal history of malignant neoplasm of pan...
        • Z85.09 Personal history of malignant neoplasm of oth...
      • Z85.1 Personal history of malignant neoplasm of tra...
        • Z85.11 Personal history of malignant neoplasm of bro...
          • Z85.110 Personal history of malignant carcinoid tumor...
          • Z85.118 Personal history of other malignant neoplasm ...
        • Z85.12 Personal history of malignant neoplasm of tra...
      • Z85.2 Personal history of malignant neoplasm of oth...
        • Z85.20 Personal history of malignant neoplasm of uns...
        • Z85.21 Personal history of malignant neoplasm of lar...
        • Z85.22 Personal history of malignant neoplasm of nas...
        • Z85.23 Personal history of malignant neoplasm of thy...
          • Z85.230 Personal history of malignant carcinoid tumor...
          • Z85.238 Personal history of other malignant neoplasm ...
        • Z85.29 Personal history of malignant neoplasm of oth...
      • Z85.3 Personal history of malignant neoplasm of bre...
      • Z85.4 Personal history of malignant neoplasm of gen...
        • Z85.40 Personal history of malignant neoplasm of uns...
        • Z85.41 Personal history of malignant neoplasm of cer...
        • Z85.42 Personal history of malignant neoplasm of oth...
        • Z85.43 Personal history of malignant neoplasm of ova...
        • Z85.44 Personal history of malignant neoplasm of oth...
        • Z85.45 Personal history of malignant neoplasm of uns...
        • Z85.46 Personal history of malignant neoplasm of pro...
        • Z85.47 Personal history of malignant neoplasm of tes...
        • Z85.48 Personal history of malignant neoplasm of epi...
        • Z85.49 Personal history of malignant neoplasm of oth...
      • Z85.5 Personal history of malignant neoplasm of uri...
        • Z85.50 Personal history of malignant neoplasm of uns...
        • Z85.51 Personal history of malignant neoplasm of bla...
        • Z85.52 Personal history of malignant neoplasm of kid...
          • Z85.520 Personal history of malignant carcinoid tumor...
          • Z85.528 Personal history of other malignant neoplasm ...
        • Z85.53 Personal history of malignant neoplasm of ren...
        • Z85.54 Personal history of malignant neoplasm of ure...
        • Z85.59 Personal history of malignant neoplasm of oth...
      • Z85.6 Personal history of leukemia
      • Z85.7 Personal history of other malignant neoplasms...
        • Z85.71 Personal history of Hodgkin lymphoma
        • Z85.72 Personal history of non-Hodgkin lymphomas
        • Z85.79 Personal history of other malignant neoplasms...
      • Z85.8 Personal history of malignant neoplasms of ot...
        • Z85.81 Personal history of malignant neoplasm of lip...
          • Z85.810 Personal history of malignant neoplasm of ton...
          • Z85.818 Personal history of malignant neoplasm of oth...
          • Z85.819 Personal history of malignant neoplasm of uns...
        • Z85.82 Personal history of malignant neoplasm of ski...
          • Z85.820 Personal history of malignant melanoma of ski...
          • Z85.821 Personal history of Merkel cell carcinoma
          • Z85.828 Personal history of other malignant neoplasm ...
        • Z85.83 Personal history of malignant neoplasm of bon...
          • Z85.830 Personal history of malignant neoplasm of bon...
          • Z85.831 Personal history of malignant neoplasm of sof...
        • Z85.84 Personal history of malignant neoplasm of eye...
          • Z85.840 Personal history of malignant neoplasm of eye...
          • Z85.841 Personal history of malignant neoplasm of bra...
          • Z85.848 Personal history of malignant neoplasm of oth...
        • Z85.85 Personal history of malignant neoplasm of end...
          • Z85.850 Personal history of malignant neoplasm of thy...
          • Z85.858 Personal history of malignant neoplasm of oth...
        • Z85.89 Personal history of malignant neoplasm of oth...
      • Z85.9 Personal history of malignant neoplasm, unspe...
    Z85.-
    )
Code First
Code First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • , if applicable, any current malignant neoplasm (
    ICD-10-CM Diagnosis Code C00

    Malignant neoplasm of lip

      2016 2017 2018 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • malignant melanoma of lip (C43.0)
    • Merkel cell carcinoma of lip (C4A.0)
    • other and unspecified malignant neoplasm of skin of lip (C44.0-)
    Use Additional
    • code to identify:
    • alcohol abuse and dependence (F10.-)
    • history of tobacco dependence (Z87.891)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
    C00
    -
    ICD-10-CM Diagnosis Code C75

    Malignant neoplasm of other endocrine glands and related structures

      2016 2017 2018 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • malignant carcinoid tumors (C7A.0-)
    • malignant neoplasm of adrenal gland (C74.-)
    • malignant neoplasm of endocrine pancreas (C25.4)
    • malignant neoplasm of islets of Langerhans (C25.4)
    • malignant neoplasm of ovary (C56.-)
    • malignant neoplasm of testis (C62.-)
    • malignant neoplasm of thymus (C37)
    • malignant neoplasm of thyroid gland (C73)
    • malignant neuroendocrine tumors (C7A.-)
    C75
    , C81-C96
    ICD-10-CM Range C81-C96

    Malignant neoplasms of lymphoid, hematopoietic and related tissue

    Type 2 Excludes
    • Kaposi's sarcoma of lymph nodes (C46.3)
    • secondary and unspecified neoplasm of lymph nodes (C77.-)
    • secondary neoplasm of bone marrow (C79.52)
    • secondary neoplasm of spleen (C78.89)
    • C81 Hodgkin lymphoma
    • C82 Follicular lymphoma
    • C83 Non-follicular lymphoma
    • C84 Mature T/NK-cell lymphomas
    • C85 Other specified and unspecified types of...
    • C86 Other specified types of T/NK-cell lymph...
    • C88 Malignant immunoproliferative diseases a...
    • C90 Multiple myeloma and malignant plasma ce...
    • C91 Lymphoid leukemia
    • C92 Myeloid leukemia
    • C93 Monocytic leukemia
    • C94 Other leukemias of specified cell type
    • C95 Leukemia of unspecified cell type
    • C96 Other and unspecified malignant neoplasm...
    )
The following code(s) above Z15.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to Z15.0:
  • Z00-Z99
    2018 ICD-10-CM Range Z00-Z99

    Factors influencing health status and contact with health services

    Note
    • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
    • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
    • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.
    Factors influencing health status and contact with health services
  • Z15
    ICD-10-CM Diagnosis Code Z15

    Genetic susceptibility to disease

      2016 2017 2018 Non-Billable/Non-Specific Code
    Includes
    • confirmed abnormal gene
    Type 1 Excludes
    Use Additional
    • code, if applicable, for any associated family history of the disease (Z80-Z84)
    Genetic susceptibility to disease
Code History
Code annotations containing back-references to Z15.0:
ICD-10-CM Codes Adjacent To Z15.0
Z13.88 Encounter for screening for disorder due to exposure to contaminants
Z13.89 Encounter for screening for other disorder
Z13.9 Encounter for screening, unspecified
Z14 Genetic carrier
Z14.0 Hemophilia A carrier
Z14.01 Asymptomatic hemophilia A carrier
Z14.02 Symptomatic hemophilia A carrier
Z14.1 Cystic fibrosis carrier
Z14.8 Genetic carrier of other disease
Z15 Genetic susceptibility to disease
Z15.0 Genetic susceptibility to malignant neoplasm
Z15.01 …… of breast
Z15.02 …… of ovary
Z15.03 …… of prostate
Z15.04 …… of endometrium
Z15.09 Genetic susceptibility to other malignant neoplasm
Z15.8 Genetic susceptibility to other disease
Z15.81 Genetic susceptibility to multiple endocrine neoplasia [MEN]
Z15.89 Genetic susceptibility to other disease
Z16 Resistance to antimicrobial drugs
Z16.1 Resistance to beta lactam antibiotics

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.