2017/18 ICD-10-CM Diagnosis Code Z79.81

Long term (current) use of agents affecting estrogen receptors and estrogen levels

Use Additional
Use Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code, if applicable, to identify:
  • estrogen receptor positive status (
    ICD-10-CM Diagnosis Code Z17.0

    Estrogen receptor positive status [ER+]

      2016 2017 2018 Billable/Specific Code POA Exempt
    Z17.0
    )
  • family history of breast cancer (
    ICD-10-CM Diagnosis Code Z80.3

    Family history of malignant neoplasm of breast

      2016 2017 2018 Billable/Specific Code POA Exempt
    Applicable To
    • Conditions classifiable to C50.-
    Z80.3
    )
  • genetic susceptibility to malignant neoplasm (cancer) (
    ICD-10-CM Diagnosis Code Z15.0

    Genetic susceptibility to malignant neoplasm

      2016 2017 2018 Non-Billable/Non-Specific Code
    Code First
    • , if applicable, any current malignant neoplasm (C00-C75, C81-C96)
    Use Additional
    • code, if applicable, for any personal history of malignant neoplasm (Z85.-)
    Z15.0-
    )
  • personal history of breast cancer (
    ICD-10-CM Diagnosis Code Z85.3

    Personal history of malignant neoplasm of breast

      2016 2017 2018 Billable/Specific Code POA Exempt
    Applicable To
    • Conditions classifiable to C50.-
    Z85.3
    )
  • personal history of prostate cancer (
    ICD-10-CM Diagnosis Code Z85.46

    Personal history of malignant neoplasm of prostate

      2016 2017 2018 Billable/Specific Code Male Dx POA Exempt
    Z85.46
    )
  • postmenopausal status (
    ICD-10-CM Diagnosis Code Z78.0

    Asymptomatic menopausal state

      2016 2017 2018 Billable/Specific Code Adult Dx (15-124 years) Female Dx POA Exempt
    Applicable To
    • Menopausal state NOS
    • Postmenopausal status NOS
    Type 2 Excludes
    • symptomatic menopausal state (N95.1)
    Z78.0
    )
Code First
Code First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • , if applicable:
  • malignant neoplasm of breast (
    ICD-10-CM Diagnosis Code C50
    • C50 Malignant neoplasm of breast
      • C50.0 Malignant neoplasm of nipple and areola
        • C50.01 Malignant neoplasm of nipple and areola, fema...
          • C50.011 Malignant neoplasm of nipple and areola, righ...
          • C50.012 Malignant neoplasm of nipple and areola, left...
          • C50.019 Malignant neoplasm of nipple and areola, unsp...
        • C50.02 Malignant neoplasm of nipple and areola, male...
          • C50.021 Malignant neoplasm of nipple and areola, righ...
          • C50.022 Malignant neoplasm of nipple and areola, left...
          • C50.029 Malignant neoplasm of nipple and areola, unsp...
      • C50.1 Malignant neoplasm of central portion of brea...
        • C50.11 Malignant neoplasm of central portion of brea...
          • C50.111 Malignant neoplasm of central portion of righ...
          • C50.112 Malignant neoplasm of central portion of left...
          • C50.119 Malignant neoplasm of central portion of unsp...
        • C50.12 Malignant neoplasm of central portion of brea...
          • C50.121 Malignant neoplasm of central portion of righ...
          • C50.122 Malignant neoplasm of central portion of left...
          • C50.129 Malignant neoplasm of central portion of unsp...
      • C50.2 Malignant neoplasm of upper-inner quadrant of...
        • C50.21 Malignant neoplasm of upper-inner quadrant of...
          • C50.211 Malignant neoplasm of upper-inner quadrant of...
          • C50.212 Malignant neoplasm of upper-inner quadrant of...
          • C50.219 Malignant neoplasm of upper-inner quadrant of...
        • C50.22 Malignant neoplasm of upper-inner quadrant of...
          • C50.221 Malignant neoplasm of upper-inner quadrant of...
          • C50.222 Malignant neoplasm of upper-inner quadrant of...
          • C50.229 Malignant neoplasm of upper-inner quadrant of...
      • C50.3 Malignant neoplasm of lower-inner quadrant of...
        • C50.31 Malignant neoplasm of lower-inner quadrant of...
          • C50.311 Malignant neoplasm of lower-inner quadrant of...
          • C50.312 Malignant neoplasm of lower-inner quadrant of...
          • C50.319 Malignant neoplasm of lower-inner quadrant of...
        • C50.32 Malignant neoplasm of lower-inner quadrant of...
          • C50.321 Malignant neoplasm of lower-inner quadrant of...
          • C50.322 Malignant neoplasm of lower-inner quadrant of...
          • C50.329 Malignant neoplasm of lower-inner quadrant of...
      • C50.4 Malignant neoplasm of upper-outer quadrant of...
        • C50.41 Malignant neoplasm of upper-outer quadrant of...
          • C50.411 Malignant neoplasm of upper-outer quadrant of...
          • C50.412 Malignant neoplasm of upper-outer quadrant of...
          • C50.419 Malignant neoplasm of upper-outer quadrant of...
        • C50.42 Malignant neoplasm of upper-outer quadrant of...
          • C50.421 Malignant neoplasm of upper-outer quadrant of...
          • C50.422 Malignant neoplasm of upper-outer quadrant of...
          • C50.429 Malignant neoplasm of upper-outer quadrant of...
      • C50.5 Malignant neoplasm of lower-outer quadrant of...
        • C50.51 Malignant neoplasm of lower-outer quadrant of...
          • C50.511 Malignant neoplasm of lower-outer quadrant of...
          • C50.512 Malignant neoplasm of lower-outer quadrant of...
          • C50.519 Malignant neoplasm of lower-outer quadrant of...
        • C50.52 Malignant neoplasm of lower-outer quadrant of...
          • C50.521 Malignant neoplasm of lower-outer quadrant of...
          • C50.522 Malignant neoplasm of lower-outer quadrant of...
          • C50.529 Malignant neoplasm of lower-outer quadrant of...
      • C50.6 Malignant neoplasm of axillary tail of breast...
        • C50.61 Malignant neoplasm of axillary tail of breast...
          • C50.611 Malignant neoplasm of axillary tail of right ...
          • C50.612 Malignant neoplasm of axillary tail of left f...
          • C50.619 Malignant neoplasm of axillary tail of unspec...
        • C50.62 Malignant neoplasm of axillary tail of breast...
          • C50.621 Malignant neoplasm of axillary tail of right ...
          • C50.622 Malignant neoplasm of axillary tail of left m...
          • C50.629 Malignant neoplasm of axillary tail of unspec...
      • C50.8 Malignant neoplasm of overlapping sites of br...
        • C50.81 Malignant neoplasm of overlapping sites of br...
          • C50.811 Malignant neoplasm of overlapping sites of ri...
          • C50.812 Malignant neoplasm of overlapping sites of le...
          • C50.819 Malignant neoplasm of overlapping sites of un...
        • C50.82 Malignant neoplasm of overlapping sites of br...
          • C50.821 Malignant neoplasm of overlapping sites of ri...
          • C50.822 Malignant neoplasm of overlapping sites of le...
          • C50.829 Malignant neoplasm of overlapping sites of un...
      • C50.9 Malignant neoplasm of breast of unspecified s...
        • C50.91 Malignant neoplasm of breast of unspecified s...
          • C50.911 Malignant neoplasm of unspecified site of rig...
          • C50.912 Malignant neoplasm of unspecified site of lef...
          • C50.919 Malignant neoplasm of unspecified site of uns...
        • C50.92 Malignant neoplasm of breast of unspecified s...
          • C50.921 Malignant neoplasm of unspecified site of rig...
          • C50.922 Malignant neoplasm of unspecified site of lef...
          • C50.929 Malignant neoplasm of unspecified site of uns...
    C50.-
    )
  • malignant neoplasm of prostate (
    ICD-10-CM Diagnosis Code C61

    Malignant neoplasm of prostate

      2016 2017 2018 Billable/Specific Code Male Dx
    Type 1 Excludes
    • malignant neoplasm of seminal vesicle (C63.7)
    Use Additional
    • code to identify:
    • hormone sensitivity status (Z19.1-Z19.2)
    • rising PSA following treatment for malignant neoplasm of prostate (R97.21)
    C61
    )
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as Z79.81. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • hormone replacement therapy (
    ICD-10-CM Diagnosis Code Z79.890

    Hormone replacement therapy

      2016 2017 2018 - Revised Code Billable/Specific Code POA Exempt
    Z79.890
    )
The following code(s) above Z79.81 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to Z79.81:
  • Z00-Z99
    2018 ICD-10-CM Range Z00-Z99

    Factors influencing health status and contact with health services

    Note
    • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
    • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
    • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.
    Factors influencing health status and contact with health services
  • Z77-Z99
    2018 ICD-10-CM Range Z77-Z99

    Persons with potential health hazards related to family and personal history and certain conditions influencing health status

    Code Also
    • any follow-up examination (Z08-Z09)
    Persons with potential health hazards related to family and personal history and certain conditions influencing health status
  • Z79
    ICD-10-CM Diagnosis Code Z79

    Long term (current) drug therapy

      2016 2017 2018 Non-Billable/Non-Specific Code
    Code Also
    • any therapeutic drug level monitoring (Z51.81)
    Includes
    • long term (current) drug use for prophylactic purposes
    Type 2 Excludes
    • drug abuse and dependence (F11-F19)
    • drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)
    • long term (current) use of oral antidiabetic drugs (Z79.84)
    • long term (current) use of oral hypoglycemic drugs (Z79.84)
    Long term (current) drug therapy
Code History
ICD-10-CM Codes Adjacent To Z79.81
Z79.01 Long term (current) use of anticoagulants
Z79.02 Long term (current) use of antithrombotics/antiplatelets
Z79.1 Long term (current) use of non-steroidal anti-inflammatories (NSAID)
Z79.2 Long term (current) use of antibiotics
Z79.3 Long term (current) use of hormonal contraceptives
Z79.4 Long term (current) use of insulin
Z79.5 Long term (current) use of steroids
Z79.51 Long term (current) use of inhaled steroids
Z79.52 Long term (current) use of systemic steroids
Z79.8 Other long term (current) drug therapy
Z79.81 Long term (current) use of agents affecting estrogen receptors and estrogen levels
Z79.810 Long term (current) use of selective estrogen receptor modulators (SERMs)
Z79.811 Long term (current) use of aromatase inhibitors
Z79.818 Long term (current) use of other agents affecting estrogen receptors and estrogen levels
Z79.82 Long term (current) use of aspirin
Z79.83 Long term (current) use of bisphosphonates
Z79.84 Long term (current) use of oral hypoglycemic drugs
Z79.89 Other long term (current) drug therapy
Z79.890 Hormone replacement therapy
Z79.891 Long term (current) use of opiate analgesic
Z79.899 Other long term (current) drug therapy

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.