2023 ICD-10-CM Diagnosis Code A41

Other sepsis

    2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
  • A41 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2023 edition of ICD-10-CM A41 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of A41 - other international versions of ICD-10 A41 may differ.
Code First
Code First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • postprocedural sepsis (
    ICD-10-CM Diagnosis Code T81.4

    Infection following a procedure

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Applicable To
    • Wound abscess following a procedure
    Type 2 Excludes
    Use Additional
    • code to identify infection
    T81.4-
    )
  • sepsis during labor (
    ICD-10-CM Diagnosis Code O75.3

    Other infection during labor

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Maternity Dx (12-55 years) Female Dx
    Applicable To
    • Sepsis during labor
    Use Additional
    • code (B95-B97), to identify infectious agent
    O75.3
    )
  • sepsis following abortion, ectopic or molar pregnancy (
    ICD-10-CM Diagnosis Code O03

    Spontaneous abortion

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Includes
    • miscarriage
    Note
    • Incomplete abortion includes retained products of conception following spontaneous abortion
    O03
    -
    ICD-10-CM Diagnosis Code O07

    Failed attempted termination of pregnancy

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Includes
    • failure of attempted induction of termination of pregnancy
    • incomplete elective abortion
    Type 1 Excludes
    • incomplete spontaneous abortion (O03.0-)
    O07
    ,
    ICD-10-CM Diagnosis Code O08.0

    Genital tract and pelvic infection following ectopic and molar pregnancy

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Maternity Dx (12-55 years) Female Dx
    Applicable To
    • Endometritis following ectopic and molar pregnancy
    • Oophoritis following ectopic and molar pregnancy
    • Parametritis following ectopic and molar pregnancy
    • Pelvic peritonitis following ectopic and molar pregnancy
    • Salpingitis following ectopic and molar pregnancy
    • Salpingo-oophoritis following ectopic and molar pregnancy
    Type 1 Excludes
    • sepsis following ectopic and molar pregnancy (O08.82)
    • urinary tract infection (O08.83)
    O08.0
    )
  • sepsis following immunization (
    ICD-10-CM Diagnosis Code T88.0

    Infection following immunization

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Applicable To
    • Sepsis following immunization
    T88.0
    )
  • sepsis following infusion, transfusion or therapeutic injection (
    ICD-10-CM Diagnosis Code T80.2

    Infections following infusion, transfusion and therapeutic injection

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 2 Excludes
    Use Additional
    • code to identify the specific infection, such as:
    • sepsis (A41.9)
    T80.2-
    )
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as A41. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • bacteremia NOS (
    ICD-10-CM Diagnosis Code R78.81

    Bacteremia

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Type 1 Excludes
    • sepsis-code to specified infection
    R78.81
    )
  • neonatal (
    ICD-10-CM Diagnosis Code P36
    • P36 Bacterial sepsis of newborn
      • P36.0 Sepsis of newborn due to streptococcus, group...
      • P36.1 Sepsis of newborn due to other and unspecifie...
        • P36.10 Sepsis of newborn due to unspecified streptoc...
        • P36.19 Sepsis of newborn due to other streptococci
      • P36.2 Sepsis of newborn due to Staphylococcus aureu...
      • P36.3 Sepsis of newborn due to other and unspecifie...
        • P36.30 Sepsis of newborn due to unspecified staphylo...
        • P36.39 Sepsis of newborn due to other staphylococci
      • P36.4 Sepsis of newborn due to Escherichia coli
      • P36.5 Sepsis of newborn due to anaerobes
      • P36.8 Other bacterial sepsis of newborn
      • P36.9 Bacterial sepsis of newborn, unspecified
    P36.-
    )
  • puerperal sepsis (
    ICD-10-CM Diagnosis Code O85

    Puerperal sepsis

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Maternity Dx (12-55 years) Female Dx
    Applicable To
    • Postpartum sepsis
    • Puerperal peritonitis
    • Puerperal pyemia
    Type 1 Excludes
    • fever of unknown origin following delivery (O86.4)
    • genital tract infection following delivery (O86.1-)
    • obstetric pyemic and septic embolism (O88.3-)
    • puerperal septic thrombophlebitis (O86.81)
    • urinary tract infection following delivery (O86.2-)
    Type 2 Excludes
    • sepsis during labor (O75.3)
    Use Additional
    • code (B95-B97), to identify infectious agent
    O85
    )
  • streptococcal sepsis (
    ICD-10-CM Diagnosis Code A40
    • A40 Streptococcal sepsis
      • A40.0 Sepsis due to streptococcus, group A
      • A40.1 Sepsis due to streptococcus, group B
      • A40.3 Sepsis due to Streptococcus pneumoniae
      • A40.8 Other streptococcal sepsis
      • A40.9 Streptococcal sepsis, unspecified
    A40.-
    )
Type 2 Excludes
Type 2 Excludes Help
A type 2 excludes note represents "not included here". A type 2 excludes note indicates that the condition excluded is not part of the condition it is excluded from but a patient may have both conditions at the same time. When a type 2 excludes note appears under a code it is acceptable to use both the code (A41) and the excluded code together.
  • sepsis (due to) (in) actinomycotic (
    ICD-10-CM Diagnosis Code A42.7

    Actinomycotic sepsis

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    A42.7
    )
  • sepsis (due to) (in) anthrax (
    ICD-10-CM Diagnosis Code A22.7

    Anthrax sepsis

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    A22.7
    )
  • sepsis (due to) (in) candidal (
    ICD-10-CM Diagnosis Code B37.7

    Candidal sepsis

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Disseminated candidiasis
    • Systemic candidiasis
    B37.7
    )
  • sepsis (due to) (in) Erysipelothrix (
    ICD-10-CM Diagnosis Code A26.7

    Erysipelothrix sepsis

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    A26.7
    )
  • sepsis (due to) (in) extraintestinal yersiniosis (
    ICD-10-CM Diagnosis Code A28.2

    Extraintestinal yersiniosis

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Type 1 Excludes
    • enteritis due to Yersinia enterocolitica (A04.6)
    • plague (A20.-)
    A28.2
    )
  • sepsis (due to) (in) gonococcal (
    ICD-10-CM Diagnosis Code A54.86

    Gonococcal sepsis

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    A54.86
    )
  • sepsis (due to) (in) herpesviral (
    ICD-10-CM Diagnosis Code B00.7

    Disseminated herpesviral disease

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Herpesviral sepsis
    B00.7
    )
  • sepsis (due to) (in) listerial (
    ICD-10-CM Diagnosis Code A32.7

    Listerial sepsis

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    A32.7
    )
  • sepsis (due to) (in) melioidosis (
    ICD-10-CM Diagnosis Code A24.1

    Acute and fulminating melioidosis

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Melioidosis pneumonia
    • Melioidosis sepsis
    A24.1
    )
  • sepsis (due to) (in) meningococcal (
    ICD-10-CM Diagnosis Code A39.2

    Acute meningococcemia

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    A39.2-
    ICD-10-CM Diagnosis Code A39.4

    Meningococcemia, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    A39.4
    )
  • sepsis (due to) (in) plague (
    ICD-10-CM Diagnosis Code A20.7

    Septicemic plague

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    A20.7
    )
  • sepsis (due to) (in) tularemia (
    ICD-10-CM Diagnosis Code A21.7

    Generalized tularemia

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    A21.7
    )
  • toxic shock syndrome (
    ICD-10-CM Diagnosis Code A48.3

    Toxic shock syndrome

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Type 1 Excludes
    Use Additional
    • code to identify the organism (B95, B96)
    A48.3
    )
The following code(s) above A41 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to A41:
  • A00-B99
    2023 ICD-10-CM Range A00-B99

    Certain infectious and parasitic diseases

    Includes
    • diseases generally recognized as communicable or transmissible
    Type 1 Excludes
    • certain localized infections - see body system-related chapters
    Type 2 Excludes
    • carrier or suspected carrier of infectious disease (Z22.-)
    • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
    • infectious and parasitic diseases specific to the perinatal period (P35-P39)
    • influenza and other acute respiratory infections (J00-J22)
    Use Additional
    • code to identify resistance to antimicrobial drugs (Z16.-)
    Certain infectious and parasitic diseases
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
Code annotations containing back-references to A41:
  • Code First: I5A
    ICD-10-CM Diagnosis Code I5A

    Non-ischemic myocardial injury (non-traumatic)

      2022 - New Code 2023 Billable/Specific Code
    Applicable To
    • Acute (non-ischemic) myocardial injury
    • Chronic (non-ischemic) myocardial injury
    • Unspecified (non-ischemic) myocardial injury
    Code First
    • the underlying cause, if known and applicable, such as:
    • acute kidney failure (N17.-)
    • acute myocarditis (I40.-)
    • cardiomyopathy (I42.-)
    • chronic kidney disease (CKD) (N18.-)
    • heart failure (I50.-)
    • hypertensive urgency (I16.0)
    • nonrheumatic aortic valve disorders (I35.-)
    • paroxysmal tachycardia (I47.-)
    • pulmonary embolism (I26.-)
    • pulmonary hypertension (I27.0, I27.2-)
    • sepsis (A41.-)
    • takotsubo syndrome (I51.81)
    Type 1 Excludes
    • acute myocardial infarction (I21.-)
    • injury of heart (S26.-)
    Type 2 Excludes
    • other acute ischemic heart diseases (I24.-)
  • Use Additional: J95.02
    , K94.12
    , K95.01
    , K94.22
    , K95.81
    , K94.02
    ICD-10-CM Diagnosis Code J95.02

    Infection of tracheostomy stoma

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Use Additional
    • code to identify type of infection, such as:
    • cellulitis of neck (L03.221)
    • sepsis (A40, A41.-)
    ICD-10-CM Diagnosis Code K94.12

    Enterostomy infection

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Use Additional
    • code to specify type of infection, such as:
    • cellulitis of abdominal wall (L03.311)
    • sepsis (A40.-, A41.-)
    ICD-10-CM Diagnosis Code K95.01

    Infection due to gastric band procedure

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Use Additional
    • code to specify type of infection or organism, such as:
    • bacterial and viral infectious agents (B95.-, B96.-)
    • cellulitis of abdominal wall (L03.311)
    • sepsis (A40.-, A41.-)
    ICD-10-CM Diagnosis Code K94.22

    Gastrostomy infection

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Use Additional
    • code to specify type of infection, such as:
    • cellulitis of abdominal wall (L03.311)
    • sepsis (A40.-, A41.-)
    ICD-10-CM Diagnosis Code K95.81

    Infection due to other bariatric procedure

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Use Additional
    • code to specify type of infection or organism, such as:
    • bacterial and viral infectious agents (B95.-, B96.-)
    • cellulitis of abdominal wall (L03.311)
    • sepsis (A40.-, A41.-)
    ICD-10-CM Diagnosis Code K94.02

    Colostomy infection

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Use Additional
    • code to specify type of infection, such as:
    • cellulitis of abdominal wall (L03.311)
    • sepsis (A40.-, A41.-)
ICD-10-CM Codes Adjacent To A41
A39.83 Meningococcal arthritis
A39.84 Postmeningococcal arthritis
A39.89 Other meningococcal infections
A39.9 Meningococcal infection, unspecified
A40 Streptococcal sepsis
A40.0 Sepsis due to streptococcus, group A
A40.1 Sepsis due to streptococcus, group B
A40.3 Sepsis due to Streptococcus pneumoniae
A40.8 Other streptococcal sepsis
A40.9 Streptococcal sepsis, unspecified
A41 Other sepsis
A41.0 Sepsis due to Staphylococcus aureus
A41.01 Sepsis due to Methicillin susceptible Staphylococcus aureus
A41.02 Sepsis due to Methicillin resistant Staphylococcus aureus
A41.1 Sepsis due to other specified staphylococcus
A41.2 Sepsis due to unspecified staphylococcus
A41.3 Sepsis due to Hemophilus influenzae
A41.4 Sepsis due to anaerobes
A41.5 Sepsis due to other Gram-negative organisms
A41.50 Gram-negative sepsis, unspecified
A41.51 Sepsis due to Escherichia coli [E. coli]

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.