2022 ICD-10-CM Diagnosis Code A41.9

Sepsis, unspecified organism

    2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
  • A41.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2022 edition of ICD-10-CM A41.9 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of A41.9 - other international versions of ICD-10 A41.9 may differ.
Applicable To
  • Septicemia NOS
The following code(s) above A41.9 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to A41.9:
  • A00-B99
    2022 ICD-10-CM Range A00-B99

    Certain infectious and parasitic diseases

    Includes
    • diseases generally recognized as communicable or transmissible
    Type 1 Excludes
    • certain localized infections - see body system-related chapters
    Type 2 Excludes
    • carrier or suspected carrier of infectious disease (Z22.-)
    • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
    • infectious and parasitic diseases specific to the perinatal period (P35-P39)
    • influenza and other acute respiratory infections (J00-J22)
    Use Additional
    • code to identify resistance to antimicrobial drugs (Z16.-)
    Certain infectious and parasitic diseases
  • A41
    ICD-10-CM Diagnosis Code A41

    Other sepsis

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Code First
    • postprocedural sepsis (T81.4-)
    • sepsis during labor (O75.3)
    • sepsis following abortion, ectopic or molar pregnancy (O03-O07, O08.0)
    • sepsis following immunization (T88.0)
    • sepsis following infusion, transfusion or therapeutic injection (T80.2-)
    Type 1 Excludes
    Type 2 Excludes
    • sepsis (due to) (in) actinomycotic (A42.7)
    • sepsis (due to) (in) anthrax (A22.7)
    • sepsis (due to) (in) candidal (B37.7)
    • sepsis (due to) (in) Erysipelothrix (A26.7)
    • sepsis (due to) (in) extraintestinal yersiniosis (A28.2)
    • sepsis (due to) (in) gonococcal (A54.86)
    • sepsis (due to) (in) herpesviral (B00.7)
    • sepsis (due to) (in) listerial (A32.7)
    • sepsis (due to) (in) melioidosis (A24.1)
    • sepsis (due to) (in) meningococcal (A39.2-A39.4)
    • sepsis (due to) (in) plague (A20.7)
    • sepsis (due to) (in) tularemia (A21.7)
    • toxic shock syndrome (A48.3)
    Other sepsis
Approximate Synonyms
  • Post-splenectomy septicemia
  • Postprocedural sepsis
  • Postprocedural septic shock
  • Sepsis due to infected central venous catheter
  • Sepsis due to urinary tract infection
  • Sepsis related to central venous catheter
  • Sepsis with septicemia
  • Sepsis without acute organ dysfunction
  • Sepsis without acute organ dysfunction due to gram positive bacteria
  • Sepsis without acute organ dysfunction due to septicemia, final identification pending
  • Septic pulmonary embolism
  • Septic pulmonary embolism (blood clot in lung)
  • Septic shock
  • Septic shock acute organ dysfunction
  • Septic shock after procedure
  • Septic shock with acute organ dysfunction
  • Septic shock with acute organ dysfunction due to gram positive coccus
  • Septic shock with acute organ dysfunction due to septicemia, final identification pending
  • Septicemia after splenectomy
  • Septicemia associated with central venous catheter
  • Septicemia due to central venous catheter
  • Severe sepsis acute organ dysfunction
  • Severe sepsis with acute organ dysfunction
  • Severe sepsis with acute organ dysfunction due to gram positive bacteria
  • Severe sepsis with acute organ dysfunction due to septicemia, final identification pending
  • Systemic inflammatory response syndrome
  • Systemic inflammatory response syndrome from infection
  • Urosepsis
Clinical Information
  • (sep-sis) the presence of bacteria or their toxins in the blood or tissues.
  • A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock.
  • Disease caused by the spread of bacteria and their toxins in the bloodstream.
  • Disease caused by the spread of bacteria and their toxins in the bloodstream. Also called blood poisoning.
  • Systemic disease associated with presence and persistance of pathogenic microorganisms or their toxins in the blood.
  • Systemic disease associated with the presence of pathogenic microorganisms or their toxins in the blood.
  • The presence of pathogenic microorganisms in the blood stream causing a rapidly progressing systemic reaction that may lead to shock. Symptoms include fever, chills, tachycardia, and increased respiratory rate. It is a medical emergency that requires urgent medical attention.
ICD-10-CM A41.9 is grouped within Diagnostic Related Group(s) (MS-DRG v39.0):
  • 791 Prematurity with major problems
  • 793 Full term neonate with major problems
  • 870 Septicemia or severe sepsis with mv >96 hours
  • 871 Septicemia or severe sepsis without mv >96 hours with mcc
  • 872 Septicemia or severe sepsis without mv >96 hours without mcc
  • 974 Hiv with major related condition with mcc
  • 975 Hiv with major related condition with cc
  • 976 Hiv with major related condition without cc/mcc

Convert A41.9 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
Code annotations containing back-references to A41.9:
  • Code First: N08
    , N16
    , R65.2
    ICD-10-CM Diagnosis Code N08

    Glomerular disorders in diseases classified elsewhere

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Manifestation Code
    Applicable To
    • Glomerulonephritis
    • Nephritis
    • Nephropathy
    Code First
    Type 1 Excludes
    • glomerulonephritis, nephritis and nephropathy (in):
    • antiglomerular basement membrane disease (M31.0)
    • diabetes (E08-E13 with .21)
    • gonococcal (A54.21)
    • Goodpasture's syndrome (M31.0)
    • hemolytic-uremic syndrome (D59.3)
    • lupus (M32.14)
    • mumps (B26.83)
    • syphilis (A52.75)
    • systemic lupus erythematosus (M32.14)
    • Wegener's granulomatosis (M31.31)
    • pyelonephritis in diseases classified elsewhere (N16)
    • renal tubulo-interstitial disorders classified elsewhere (N16)
    ICD-10-CM Diagnosis Code N16

    Renal tubulo-interstitial disorders in diseases classified elsewhere

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Manifestation Code
    Applicable To
    • Pyelonephritis
    • Tubulo-interstitial nephritis
    Code First
    Type 1 Excludes
    • diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84)
    • pyelonephritis and tubulo-interstitial nephritis in candidiasis (B37.49)
    • pyelonephritis and tubulo-interstitial nephritis in cystinosis (E72.04)
    • pyelonephritis and tubulo-interstitial nephritis in salmonella infection (A02.25)
    • pyelonephritis and tubulo-interstitial nephritis in sarcoidosis (D86.84)
    • pyelonephritis and tubulo-interstitial nephritis in Sjogren syndrome (M35.04)
    • pyelonephritis and tubulo-interstitial nephritis in systemic lupus erythematosus (M32.15)
    • pyelonephritis and tubulo-interstitial nephritis in toxoplasmosis (B58.83)
    • renal tubular degeneration in diabetes (E08-E13 with .29)
    • syphilitic pyelonephritis and tubulo-interstitial nephritis (A52.75)
    ICD-10-CM Diagnosis Code R65.2

    Severe sepsis

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Applicable To
    • Infection with associated acute organ dysfunction
    • Sepsis with acute organ dysfunction
    • Sepsis with multiple organ dysfunction
    • Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction
    Code First
    • underlying infection, such as:
    • infection following a procedure (T81.4-)
    • infections following infusion, transfusion and therapeutic injection (T80.2-)
    • puerperal sepsis (O85)
    • sepsis following complete or unspecified spontaneous abortion (O03.87)
    • sepsis following ectopic and molar pregnancy (O08.82)
    • sepsis following incomplete spontaneous abortion (O03.37)
    • sepsis following (induced) termination of pregnancy (O04.87)
    • sepsis NOS (A41.9)
    Use Additional
    • code to identify specific acute organ dysfunction, such as:
    • acute kidney failure (N17.-)
    • acute respiratory failure (J96.0-)
    • critical illness myopathy (G72.81)
    • critical illness polyneuropathy (G62.81)
    • disseminated intravascular coagulopathy [DIC] (D65)
    • encephalopathy (metabolic) (septic) (G93.41)
    • hepatic failure (K72.0-)
  • Type 1 Excludes: A48.3
    ICD-10-CM Diagnosis Code A48.3

    Toxic shock syndrome

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Type 1 Excludes
    Use Additional
    • code to identify the organism (B95, B96)
  • Use Additional: T80.2
    ICD-10-CM Diagnosis Code T80.2

    Infections following infusion, transfusion and therapeutic injection

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Type 2 Excludes
    Use Additional
    • code to identify the specific infection, such as:
    • sepsis (A41.9)

Diagnosis Index entries containing back-references to A41.9:

ICD-10-CM Codes Adjacent To A41.9
A41.4 Sepsis due to anaerobes
A41.5 Sepsis due to other Gram-negative organisms
A41.50 Gram-negative sepsis, unspecified
A41.51 Sepsis due to Escherichia coli [E. coli]
A41.52 Sepsis due to Pseudomonas
A41.53 Sepsis due to Serratia
A41.59 Other Gram-negative sepsis
A41.8 Other specified sepsis
A41.81 Sepsis due to Enterococcus
A41.89 Other specified sepsis
A41.9 Sepsis, unspecified organism
A42 Actinomycosis
A42.0 Pulmonary actinomycosis
A42.1 Abdominal actinomycosis
A42.2 Cervicofacial actinomycosis
A42.7 Actinomycotic sepsis
A42.8 Other forms of actinomycosis
A42.81 Actinomycotic meningitis
A42.82 Actinomycotic encephalitis
A42.89 Other forms of actinomycosis
A42.9 Actinomycosis, unspecified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.