1. ICD-10-CM Codes
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2. A00-B99 Certain infectious and parasitic diseases
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3. A50-A64 Infections with a predominantly sexual mode of transmission
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4. A52- Late syphilis
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2020 ICD-10-CM Diagnosis Code A52.3

Neurosyphilis, unspecified

2016 2017 2018 2019 2020 Billable/Specific Code

• A52.3 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2020 edition of ICD-10-CM A52.3 became effective on October 1, 2019.
• This is the American ICD-10-CM version of A52.3 - other international versions of ICD-10 A52.3 may differ.

• Neurosyphilis

• Infection of the brain or spinal cord by treponema pallidum. It occurs many years following the original infection which remained untreated. Signs and symptoms include abnormal gait, blindness, depression, paralysis, seizures and dementia.
• Infections of the central nervous system caused by treponema pallidum which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as brain infarction. The infection may also remain subclinical for several years. Late syndromes include general paresis; tabes dorsalis; meningeal syphilis; syphilitic optic atrophy; and spinal syphilis. General paresis is characterized by progressive dementia; dysarthria; tremor; myoclonus; seizures; and argyll-robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)

• 056 Degenerative nervous system disorders with mcc
• 057 Degenerative nervous system disorders without mcc

Convert A52.3 to ICD-9-CM

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change

• Gumma (syphilitic) A52.79
  ICD-10-CM Diagnosis Code A52.79

  Other symptomatic late syphilis

  2016 2017 2018 2019 2020 Billable/Specific Code

  Applicable To

  • Late syphilitic leukoderma
  • Syphilis of adrenal gland
  • Syphilis of pituitary gland
  • Syphilis of thyroid gland
  • Syphilitic splenomegaly

  Type 1 Excludes

  • syphilitic leukoderma (secondary) (A51.39)
  • central nervous system A52.3
  • neurosyphilitic A52.3
• Neurosyphilis (arrested) (early) (gumma) (late) (latent) (recurrent) (relapse) A52.3
  • remission in A52.3 (sustained)
• Syphilis, syphilitic (acquired) A53.9
  ICD-10-CM Diagnosis Code A53.9

  Syphilis, unspecified

  2016 2017 2018 2019 2020 Billable/Specific Code

  Applicable To

  • Infection due to Treponema pallidum NOS
  • Syphilis (acquired) NOS

  Type 1 Excludes

  • syphilis NOS under two years of age (A50.2)
  • central nervous system (late) (recurrent) (relapse) (tertiary) A52.3
    • remission in A52.3 (sustained)
    • serology doubtful, negative, or positive A52.3
  • early A51.9
    ICD-10-CM Diagnosis Code A51.9

    Early syphilis, unspecified

    2016 2017 2018 2019 2020 Billable/Specific Code
    • central nervous system A52.3
  • gumma NEC A52.79
    ICD-10-CM Diagnosis Code A52.79

    Other symptomatic late syphilis

    2016 2017 2018 2019 2020 Billable/Specific Code

    Applicable To

    • Late syphilitic leukoderma
    • Syphilis of adrenal gland
    • Syphilis of pituitary gland
    • Syphilis of thyroid gland
    • Syphilitic splenomegaly

    Type 1 Excludes

    • syphilitic leukoderma (secondary) (A51.39)
    • central nervous system A52.3
  • late A52.9
    ICD-10-CM Diagnosis Code A52.9

    Late syphilis, unspecified

    2016 2017 2018 2019 2020 Billable/Specific Code
    • central nervous system A52.3
  • primary A51.0
    ICD-10-CM Diagnosis Code A51.0

    Primary genital syphilis

    2016 2017 2018 2019 2020 Billable/Specific Code

    Applicable To

    • Syphilitic chancre NOS
    • central nervous system A52.3
  • tertiary A52.9
    ICD-10-CM Diagnosis Code A52.9

    Late syphilis, unspecified

    2016 2017 2018 2019 2020 Billable/Specific Code
    • central nervous system A52.3
  • nervous system, central A52.3
• Syphiloma A52.79
  ICD-10-CM Diagnosis Code A52.79

  Other symptomatic late syphilis

  2016 2017 2018 2019 2020 Billable/Specific Code

  Applicable To

  • Late syphilitic leukoderma
  • Syphilis of adrenal gland
  • Syphilis of pituitary gland
  • Syphilis of thyroid gland
  • Syphilitic splenomegaly

  Type 1 Excludes

  • syphilitic leukoderma (secondary) (A51.39)
  • central nervous system A52.3

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.