2019 ICD-10-CM Diagnosis Code B00.4

Herpesviral encephalitis

    2016 2017 2018 2019 Billable/Specific Code
  • B00.4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2019 edition of ICD-10-CM B00.4 became effective on October 1, 2018.
  • This is the American ICD-10-CM version of B00.4 - other international versions of ICD-10 B00.4 may differ.
Applicable To
  • Herpesviral meningoencephalitis
  • Simian B disease
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as B00.4. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • herpesviral encephalitis due to herpesvirus 6 and 7 (
    ICD-10-CM Diagnosis Code B10.01

    Human herpesvirus 6 encephalitis

      2016 2017 2018 2019 Billable/Specific Code
    B10.01
    ,
    ICD-10-CM Diagnosis Code B10.09

    Other human herpesvirus encephalitis

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Human herpesvirus 7 encephalitis
    B10.09
    )
  • non-simplex herpesviral encephalitis (
    ICD-10-CM Diagnosis Code B10.0

    Other human herpesvirus encephalitis

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • herpes encephalitis NOS (B00.4)
    • herpes simplex encephalitis (B00.4)
    • human herpesvirus encephalitis (B00.4)
    • simian B herpes virus encephalitis (B00.4)
    B10.0-
    )
The following code(s) above B00.4 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to B00.4:
  • A00-B99
    2019 ICD-10-CM Range A00-B99

    Certain infectious and parasitic diseases

    Includes
    • diseases generally recognized as communicable or transmissible
    Type 1 Excludes
    • certain localized infections - see body system-related chapters
    Type 2 Excludes
    • carrier or suspected carrier of infectious disease (Z22.-)
    • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
    • infectious and parasitic diseases specific to the perinatal period (P35-P39)
    • influenza and other acute respiratory infections (J00-J22)
    Use Additional
    • code to identify resistance to antimicrobial drugs (Z16.-)
    Certain infectious and parasitic diseases
  • B00
    ICD-10-CM Diagnosis Code B00

    Herpesviral [herpes simplex] infections

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • congenital herpesviral infections (P35.2)
    Type 2 Excludes
    • anogenital herpesviral infection (A60.-)
    • gammaherpesviral mononucleosis (B27.0-)
    • herpangina (B08.5)
    Herpesviral [herpes simplex] infections
Approximate Synonyms
  • Encephalitis due to human herpes simplex virus
  • Herpes simplex encephalitis
  • Herpes simplex meningoencephalitis
  • Herpetic meningoencephalitis
Clinical Information
  • A serious viral disorder characterized by infection of the brain by herpes simplex virus type 1 or 2. Herpes simplex virus type 1 affects adults, whereas herpes simplex virus type 2 affects newborns. Signs and symptoms include fever, headaches, vomiting, seizures and psychiatric manifestations.
  • An acute (or rarely chronic) inflammatory process of the brain caused by simplexvirus infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (herpesvirus 1, human) and less often by human herpesvirus 2 (herpesvirus 2, human). Clinical manifestations include fever; headache; seizures; hallucinations; behavioral alterations; aphasia; hemiparesis; and coma. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior temporal lobe and orbital regions of the frontal lobe. (from Adams et al., Principles of Neurology, 6th ed, pp751-4)
ICD-10-CM B00.4 is grouped within Diagnostic Related Group(s) (MS-DRG v36.0):
  • 023 Craniotomy with major device implant or acute complex cns pdx with mcc or chemotherapy implant or epilepsy with neurostimulator
  • 024 Craniotomy with major device implant or acute complex cns pdx without mcc
  • 097 Non-bacterial infection of nervous system except viral meningitis with mcc
  • 098 Non-bacterial infection of nervous system except viral meningitis with cc
  • 099 Non-bacterial infection of nervous system except viral meningitis without cc/mcc
  • 793 Full term neonate with major problems
  • 974 Hiv with major related condition with mcc
  • 975 Hiv with major related condition with cc
  • 976 Hiv with major related condition without cc/mcc

Convert B00.4 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
Code annotations containing back-references to B00.4:
  • Type 1 Excludes: A85
    , G05
    ICD-10-CM Diagnosis Code A85

    Other viral encephalitis, not elsewhere classified

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Includes
    • specified viral encephalomyelitis NEC
    • specified viral meningoencephalitis NEC
    Type 1 Excludes
    • benign myalgic encephalomyelitis (G93.3)
    • encephalitis due to cytomegalovirus (B25.8)
    • encephalitis due to herpesvirus NEC (B10.0-)
    • encephalitis due to herpesvirus [herpes simplex] (B00.4)
    • encephalitis due to measles virus (B05.0)
    • encephalitis due to mumps virus (B26.2)
    • encephalitis due to poliomyelitis virus (A80.-)
    • encephalitis due to zoster (B02.0)
    • lymphocytic choriomeningitis (A87.2)
    ICD-10-CM Diagnosis Code G05

    Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Code First
    • underlying disease, such as:
    • human immunodeficiency virus [HIV] disease (B20)
    • poliovirus (A80.-)
    • suppurative otitis media (H66.01-H66.4)
    • trichinellosis (B75)
    Type 1 Excludes
    • adenoviral encephalitis, myelitis and encephalomyelitis (A85.1)
    • congenital toxoplasmosis encephalitis, myelitis and encephalomyelitis (P37.1)
    • cytomegaloviral encephalitis, myelitis and encephalomyelitis (B25.8)
    • encephalitis, myelitis and encephalomyelitis (in) measles (B05.0)
    • encephalitis, myelitis and encephalomyelitis (in) systemic lupus erythematosus (M32.19)
    • enteroviral encephalitis, myelitis and encephalomyelitis (A85.0)
    • eosinophilic meningoencephalitis (B83.2)
    • herpesviral [herpes simplex] encephalitis, myelitis and encephalomyelitis (B00.4)
    • listerial encephalitis, myelitis and encephalomyelitis (A32.12)
    • meningococcal encephalitis, myelitis and encephalomyelitis (A39.81)
    • mumps encephalitis, myelitis and encephalomyelitis (B26.2)
    • postchickenpox encephalitis, myelitis and encephalomyelitis (B01.1-)
    • rubella encephalitis, myelitis and encephalomyelitis (B06.01)
    • toxoplasmosis encephalitis, myelitis and encephalomyelitis (B58.2)
    • zoster encephalitis, myelitis and encephalomyelitis (B02.0)
  • Type 2 Excludes: B10.0
    , B10.0
    , B10.0
    , B10.0
    ICD-10-CM Diagnosis Code B10.0

    Other human herpesvirus encephalitis

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • herpes encephalitis NOS (B00.4)
    • herpes simplex encephalitis (B00.4)
    • human herpesvirus encephalitis (B00.4)
    • simian B herpes virus encephalitis (B00.4)
    ICD-10-CM Diagnosis Code B10.0

    Other human herpesvirus encephalitis

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • herpes encephalitis NOS (B00.4)
    • herpes simplex encephalitis (B00.4)
    • human herpesvirus encephalitis (B00.4)
    • simian B herpes virus encephalitis (B00.4)
    ICD-10-CM Diagnosis Code B10.0

    Other human herpesvirus encephalitis

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • herpes encephalitis NOS (B00.4)
    • herpes simplex encephalitis (B00.4)
    • human herpesvirus encephalitis (B00.4)
    • simian B herpes virus encephalitis (B00.4)
    ICD-10-CM Diagnosis Code B10.0

    Other human herpesvirus encephalitis

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • herpes encephalitis NOS (B00.4)
    • herpes simplex encephalitis (B00.4)
    • human herpesvirus encephalitis (B00.4)
    • simian B herpes virus encephalitis (B00.4)

Diagnosis Index entries containing back-references to B00.4:
  • Disease, diseased - see also Syndrome
    • simian B B00.4
  • Encephalitis (chronic) (hemorrhagic) (idiopathic) (nonepidemic) (spurious) (subacute) G04.90
    ICD-10-CM Diagnosis Code G04.90

    Encephalitis and encephalomyelitis, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Ventriculitis (cerebral) NOS
  • Herpes, herpesvirus, herpetic B00.9
    ICD-10-CM Diagnosis Code B00.9

    Herpesviral infection, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Herpes simplex infection NOS
  • Meningoencephalitis G04.90
    - see also Encephalitis
    ICD-10-CM Diagnosis Code G04.90

    Encephalitis and encephalomyelitis, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Ventriculitis (cerebral) NOS

ICD-10-CM Codes Adjacent To B00.4
A98.3 Marburg virus disease
A98.4 Ebola virus disease
A98.5 Hemorrhagic fever with renal syndrome
A98.8 Other specified viral hemorrhagic fevers
A99 Unspecified viral hemorrhagic fever
B00 Herpesviral [herpes simplex] infections
B00.0 Eczema herpeticum
B00.1 Herpesviral vesicular dermatitis
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis
B00.3 Herpesviral meningitis
B00.4 Herpesviral encephalitis
B00.5 Herpesviral ocular disease
B00.50 …… unspecified
B00.51 Herpesviral iridocyclitis
B00.52 Herpesviral keratitis
B00.53 Herpesviral conjunctivitis
B00.59 Other herpesviral disease of eye
B00.7 Disseminated herpesviral disease
B00.8 Other forms of herpesviral infections
B00.81 Herpesviral hepatitis
B00.82 Herpes simplex myelitis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.