ICD-10-CM Codes
A00-B99
B00-B09
B00-
2023 ICD-10-CM Diagnosis Code B00.4

2023 ICD-10-CM Diagnosis Code B00.4

Herpesviral encephalitis

2016

2017

2018

2019

2020

2021

2022

2023

Billable/Specific Code

B00.4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
The 2023 edition of ICD-10-CM B00.4 became effective on October 1, 2022.
This is the American ICD-10-CM version of B00.4 - other international versions of ICD-10 B00.4 may differ.

Applicable To

Herpesviral meningoencephalitis
Simian B disease

Type 1 Excludes

Type 1 Excludes Help

A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as B00.4. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

herpesviral encephalitis due to herpesvirus 6 and 7 (
ICD-10-CM Diagnosis Code B10.01
Human herpesvirus 6 encephalitis
B10.01
,
ICD-10-CM Diagnosis Code B10.09
Other human herpesvirus encephalitis
Applicable To
- Human herpesvirus 7 encephalitis
B10.09
)
non-simplex herpesviral encephalitis (
ICD-10-CM Diagnosis Code B10.0
Other human herpesvirus encephalitis
Type 2 Excludes
- herpes encephalitis NOS (B00.4)
- herpes simplex encephalitis (B00.4)
- human herpesvirus encephalitis (B00.4)
- simian B herpes virus encephalitis (B00.4)
B10.0-
)

The following code(s) above B00.4 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to B00.4:

A00-B99
2023 ICD-10-CM Range A00-B99
Certain infectious and parasitic diseases
Includes
- diseases generally recognized as communicable or transmissible
Type 1 Excludes
- certain localized infections - see body system-related chapters
Type 2 Excludes
- carrier or suspected carrier of infectious disease (Z22.-)
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
- infectious and parasitic diseases specific to the perinatal period (P35-P39)
- influenza and other acute respiratory infections (J00-J22)
Use Additional
- code to identify resistance to antimicrobial drugs (Z16.-)
Certain infectious and parasitic diseases
B00
ICD-10-CM Diagnosis Code B00
Herpesviral [herpes simplex] infections
Type 1 Excludes
- congenital herpesviral infections (P35.2)
Type 2 Excludes
- anogenital herpesviral infection (A60.-)
- gammaherpesviral mononucleosis (B27.0-)
- herpangina (B08.5)
Herpesviral [herpes simplex] infections

Approximate Synonyms

Encephalitis due to human herpes simplex virus
Herpes simplex encephalitis
Herpes simplex meningoencephalitis
Herpetic meningoencephalitis

Clinical Information

A serious viral disorder characterized by infection of the brain by herpes simplex virus type 1 or 2. Herpes simplex virus type 1 affects adults, whereas herpes simplex virus type 2 affects newborns. Signs and symptoms include fever, headaches, vomiting, seizures and psychiatric manifestations.
An acute (or rarely chronic) inflammatory process of the brain caused by simplexvirus infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (herpesvirus 1, human) and less often by human herpesvirus 2 (herpesvirus 2, human). Clinical manifestations include fever; headache; seizures; hallucinations; behavioral alterations; aphasia; hemiparesis; and coma. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior temporal lobe and orbital regions of the frontal lobe. (from Adams et al., Principles of Neurology, 6th ed, pp751-4)

ICD-10-CM B00.4 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):

023 Craniotomy with major device implant or acute complex cns principal diagnosis with mcc or chemotherapy implant or epilepsy with neurostimulator
024 Craniotomy with major device implant or acute complex cns principal diagnosis without mcc
097 Non-bacterial infection of nervous system except viral meningitis with mcc
098 Non-bacterial infection of nervous system except viral meningitis with cc
099 Non-bacterial infection of nervous system except viral meningitis without cc/mcc
791 Prematurity with major problems
793 Full term neonate with major problems
974 Hiv with major related condition with mcc
975 Hiv with major related condition with cc
976 Hiv with major related condition without cc/mcc

Convert B00.4 to ICD-9-CM

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change
2023 (effective 10/1/2022): No change

Code annotations containing back-references to B00.4:

Type 1 Excludes: G05
, A85

ICD-10-CM Diagnosis Code G05
Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
Code First
- underlying disease, such as:
- congenital toxoplasmosis encephalitis, myelitis and encephalomyelitis (P37.1)
- cytomegaloviral encephalitis, myelitis and encephalomyelitis (B25.8)
- encephalitis, myelitis and encephalomyelitis (in) systemic lupus erythematosus (M32.19)
- eosinophilic meningoencephalitis (B83.2)
- human immunodeficiency virus [HIV] disease (B20)
- poliovirus (A80.-)
- suppurative otitis media (H66.01-H66.4)
- trichinellosis (B75)
Type 1 Excludes
- adenoviral encephalitis, myelitis and encephalomyelitis (A85.1)
- encephalitis, myelitis and encephalomyelitis (in) measles (B05.0)
- enteroviral encephalitis, myelitis and encephalomyelitis (A85.0)
- herpesviral [herpes simplex] encephalitis, myelitis and encephalomyelitis (B00.4)
- listerial encephalitis, myelitis and encephalomyelitis (A32.12)
- meningococcal encephalitis, myelitis and encephalomyelitis (A39.81)
- mumps encephalitis, myelitis and encephalomyelitis (B26.2)
- postchickenpox encephalitis, myelitis and encephalomyelitis (B01.1-)
- rubella encephalitis, myelitis and encephalomyelitis (B06.01)
- toxoplasmosis encephalitis, myelitis and encephalomyelitis (B58.2)
- zoster encephalitis, myelitis and encephalomyelitis (B02.0)
ICD-10-CM Diagnosis Code A85
Other viral encephalitis, not elsewhere classified
Includes
- specified viral encephalomyelitis NEC
- specified viral meningoencephalitis NEC
Type 1 Excludes
- encephalitis due to cytomegalovirus (B25.8)
- encephalitis due to herpesvirus NEC (B10.0-)
- encephalitis due to herpesvirus [herpes simplex] (B00.4)
- encephalitis due to measles virus (B05.0)
- encephalitis due to mumps virus (B26.2)
- encephalitis due to poliomyelitis virus (A80.-)
- encephalitis due to zoster (B02.0)
- lymphocytic choriomeningitis (A87.2)
- myalgic encephalomyelitis (G93.32)
Type 2 Excludes: B10.0
, B10.0
, B10.0
, B10.0

ICD-10-CM Diagnosis Code B10.0
Other human herpesvirus encephalitis
Type 2 Excludes
- herpes encephalitis NOS (B00.4)
- herpes simplex encephalitis (B00.4)
- human herpesvirus encephalitis (B00.4)
- simian B herpes virus encephalitis (B00.4)
ICD-10-CM Diagnosis Code B10.0
Other human herpesvirus encephalitis
Type 2 Excludes
- herpes encephalitis NOS (B00.4)
- herpes simplex encephalitis (B00.4)
- human herpesvirus encephalitis (B00.4)
- simian B herpes virus encephalitis (B00.4)
ICD-10-CM Diagnosis Code B10.0
Other human herpesvirus encephalitis
Type 2 Excludes
- herpes encephalitis NOS (B00.4)
- herpes simplex encephalitis (B00.4)
- human herpesvirus encephalitis (B00.4)
- simian B herpes virus encephalitis (B00.4)
ICD-10-CM Diagnosis Code B10.0
Other human herpesvirus encephalitis
Type 2 Excludes
- herpes encephalitis NOS (B00.4)
- herpes simplex encephalitis (B00.4)
- human herpesvirus encephalitis (B00.4)
- simian B herpes virus encephalitis (B00.4)

Diagnosis Index entries containing back-references to B00.4:

Disease, diseased - see also Syndrome
- simian B B00.4
Encephalitis (chronic) (hemorrhagic) (idiopathic) (nonepidemic) (spurious) (subacute) G04.90
ICD-10-CM Diagnosis Code G04.90
Encephalitis and encephalomyelitis, unspecified
Applicable To
Ventriculitis (cerebral) NOS
- herpesviral B00.4
- in (due to)
  - herpes (simplex) B00.4
Herpes, herpesvirus, herpetic B00.9
ICD-10-CM Diagnosis Code B00.9
Herpesviral infection, unspecified
Applicable To
Herpes simplex infection NOS
- encephalitis B00.4
Meningoencephalitis G04.90
- see also Encephalitis
ICD-10-CM Diagnosis Code G04.90
Encephalitis and encephalomyelitis, unspecified
Applicable To
Ventriculitis (cerebral) NOS
- herpesviral, herpetic B00.4
- in (due to)
  - herpes B00.4

ICD-10-CM Codes Adjacent To B00.4

A98.3 Marburg virus disease

A98.4 Ebola virus disease

A98.5 Hemorrhagic fever with renal syndrome

A98.8 Other specified viral hemorrhagic fevers

A99 Unspecified viral hemorrhagic fever

B00 Herpesviral [herpes simplex] infections

B00.0 Eczema herpeticum

B00.1 Herpesviral vesicular dermatitis

B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis

B00.3 Herpesviral meningitis

B00.4 Herpesviral encephalitis

B00.5 Herpesviral ocular disease

B00.50 …… unspecified

B00.51 Herpesviral iridocyclitis

B00.52 Herpesviral keratitis

B00.53 Herpesviral conjunctivitis

B00.59 Other herpesviral disease of eye

B00.7 Disseminated herpesviral disease

B00.8 Other forms of herpesviral infections

B00.81 Herpesviral hepatitis

B00.82 Herpes simplex myelitis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2023 ICD-10-CM Diagnosis Code B00.4

Herpesviral encephalitis

Human herpesvirus 6 encephalitis

Other human herpesvirus encephalitis

Other human herpesvirus encephalitis

Certain infectious and parasitic diseases

Herpesviral [herpes simplex] infections

Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere

Other viral encephalitis, not elsewhere classified

Other human herpesvirus encephalitis

Other human herpesvirus encephalitis

Other human herpesvirus encephalitis

Other human herpesvirus encephalitis

Encephalitis and encephalomyelitis, unspecified

Herpesviral infection, unspecified

Encephalitis and encephalomyelitis, unspecified