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ICD-10-CM Codes
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A00-B99
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B25-B34
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B27-
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2023 ICD-10-CM Diagnosis Code B27.0
2023 ICD-10-CM Diagnosis Code B27.0
Gammaherpesviral mononucleosis
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
- B27.0 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
- The 2023 edition of ICD-10-CM B27.0 became effective on October 1, 2022.
- This is the American ICD-10-CM version of B27.0 - other international versions of ICD-10 B27.0 may differ.
Applicable To- Mononucleosis due to Epstein-Barr virus
The following code(s) above
B27.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
B27.0:
Clinical Information
- A common, acute infection usually caused by the epstein-barr virus (herpesvirus 4, human). There is an increase in mononuclear white blood cells and other atypical lymphocytes, generalized lymphadenopathy, splenomegaly, and occasionally hepatomegaly with hepatitis.
- Acute disease characterized by fever and swollen lymph nodes and an abnormal increase of mononuclear leucocytes or monocytes in the bloodstream; not highly contagious; some believe it can be transmitted by kissing.
- Infectious mononucleosis, or "mono", is an infection caused by the epstein-barr virus. The virus spreads through saliva, which is why it's sometimes called "kissing disease." mono occurs most often in 15 to 17-year-olds. However, you can get it at any age. Symptoms of mono include
- fever
- sore throat
- swollen lymph glands
sometimes you may also have a swollen spleen. Serious problems are rare. A blood test can show if you have mono. Most people get better in two to four weeks. However, you may feel tired for a few months afterward. Treatment focuses on helping symptoms and includes medicines for pain and fever, warm salt water gargles and plenty of rest and fluids.
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- 2022 (effective 10/1/2021): No change
- 2023 (effective 10/1/2022): No change
Code annotations containing back-references to B27.0:
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Code First: K77
ICD-10-CM Diagnosis Code K77
Liver disorders in diseases classified elsewhere
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Manifestation Code
Code First- underlying disease, such as:
- amyloidosis (E85.-)
- congenital syphilis (A50.0, A50.5)
- congenital toxoplasmosis (P37.1)
- infectious mononucleosis with liver disease (B27.0-B27.9 with fifth character 9)
- schistosomiasis (B65.0-B65.9)
Type 1 Excludes- alcoholic hepatitis (K70.1-)
- alcoholic liver disease (K70.-)
- cytomegaloviral hepatitis (B25.1)
- herpesviral [herpes simplex] hepatitis (B00.81)
- mumps hepatitis (B26.81)
- sarcoidosis with liver disease (D86.89)
- secondary syphilis with liver disease (A51.45)
- syphilis (late) with liver disease (A52.74)
- toxoplasmosis (acquired) hepatitis (B58.1)
- tuberculosis with liver disease (A18.83)
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Type 1 Excludes: G63
ICD-10-CM Diagnosis Code G63
Polyneuropathy in diseases classified elsewhere
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Manifestation Code
Type 1 Excludes- polyneuropathy (in):
- diabetes mellitus (E08-E13 with .42)
- diphtheria (A36.83)
- infectious mononucleosis complicated by polyneuropathy (B27.0-B27.9 with fifth character 1)
- Lyme disease (A69.22)
- mumps (B26.84)
- postherpetic (B02.23)
- rheumatoid arthritis (M05.5-)
- scleroderma (M34.83)
- systemic lupus erythematosus (M32.19)
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Type 2 Excludes: B00, B10, B10
ICD-10-CM Diagnosis Code B00
Herpesviral [herpes simplex] infections
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
Type 1 Excludes- congenital herpesviral infections (P35.2)
Type 2 Excludes- anogenital herpesviral infection (A60.-)
- gammaherpesviral mononucleosis (B27.0-)
- herpangina (B08.5)
ICD-10-CM Diagnosis Code B10
Other human herpesviruses
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
ICD-10-CM Diagnosis Code B10
Other human herpesviruses
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
ICD-10-CM Codes Adjacent To B27.0
B26.8 Mumps with other complications
B26.89 Other mumps complications
B26.9 Mumps without complication
B27 Infectious mononucleosis
B27.0
Gammaherpesviral mononucleosis
B27.00 …… without complication
B27.09 …… with other complications
B27.1 Cytomegaloviral mononucleosis
B27.10 …… without complications
B27.19 …… with other complication
B27.8 Other infectious mononucleosis
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.