2023 ICD-10-CM Diagnosis Code C21.2

Malignant neoplasm of cloacogenic zone

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • C21.2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM C21.2 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of C21.2 - other international versions of ICD-10 C21.2 may differ.
The following code(s) above C21.2 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C21.2:
  • C00-D49
    2023 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C15-C26
    2023 ICD-10-CM Range C15-C26

    Malignant neoplasms of digestive organs

    Type 1 Excludes
    • Kaposi's sarcoma of gastrointestinal sites (C46.4)
    Type 2 Excludes
    • gastrointestinal stromal tumors (C49.A-)
    Malignant neoplasms of digestive organs
  • C21
    ICD-10-CM Diagnosis Code C21

    Malignant neoplasm of anus and anal canal

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 2 Excludes
    Malignant neoplasm of anus and anal canal
Approximate Synonyms
  • Cancer cloacogenic zone
  • Primary malignant neoplasm of cloacogenic zone
ICD-10-CM C21.2 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 374 Digestive malignancy with mcc
  • 375 Digestive malignancy with cc
  • 376 Digestive malignancy without cc/mcc

Convert C21.2 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to C21.2:

ICD-10-CM Codes Adjacent To C21.2
C18.5 Malignant neoplasm of splenic flexure
C18.6 Malignant neoplasm of descending colon
C18.7 Malignant neoplasm of sigmoid colon
C18.8 Malignant neoplasm of overlapping sites of colon
C18.9 Malignant neoplasm of colon, unspecified
C19 Malignant neoplasm of rectosigmoid junction
C20 Malignant neoplasm of rectum
C21 Malignant neoplasm of anus and anal canal
C21.0 Malignant neoplasm of anus, unspecified
C21.1 Malignant neoplasm of anal canal
C21.2 Malignant neoplasm of cloacogenic zone
C21.8 Malignant neoplasm of overlapping sites of rectum, anus and anal canal
C22 Malignant neoplasm of liver and intrahepatic bile ducts
C22.0 Liver cell carcinoma
C22.1 Intrahepatic bile duct carcinoma
C22.2 Hepatoblastoma
C22.3 Angiosarcoma of liver
C22.4 Other sarcomas of liver
C22.7 Other specified carcinomas of liver
C22.8 Malignant neoplasm of liver, primary, unspecified as to type
C22.9 Malignant neoplasm of liver, not specified as primary or secondary

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.