2023 ICD-10-CM Diagnosis Code C40.21

Malignant neoplasm of long bones of right lower limb

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • C40.21 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM C40.21 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of C40.21 - other international versions of ICD-10 C40.21 may differ.
The following code(s) above C40.21 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C40.21:
  • C00-D49
    2023 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C40-C41
    2023 ICD-10-CM Range C40-C41

    Malignant neoplasms of bone and articular cartilage

    Includes
    • malignant neoplasm of cartilage (articular) (joint)
    • malignant neoplasm of periosteum
    Type 1 Excludes
    • malignant neoplasm of bone marrow NOS (C96.9)
    • malignant neoplasm of synovia (C49.-)
    Malignant neoplasms of bone and articular cartilage
  • C40
    ICD-10-CM Diagnosis Code C40

    Malignant neoplasm of bone and articular cartilage of limbs

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Use Additional
    • code to identify major osseous defect, if applicable (M89.7-)
    Malignant neoplasm of bone and articular cartilage of limbs
Approximate Synonyms
  • Bone cancer, bilateral legs
  • Cancer, bone of right leg
  • Chondrosarcoma, bilateral legs
  • Chondrosarcoma, r leg
  • Ewings sarcoma, bilateral legs
  • Ewings sarcoma, r leg
  • Osteosarcoma, bilateral legs
  • Osteosarcoma, r leg
  • Primary chondrosarcoma of bilateral lower limbs
  • Primary chondrosarcoma of right lower limb
  • Primary ewing's sarcoma of bilateral lower limbs
  • Primary ewing's sarcoma of right lower limb
  • Primary malignant neoplasm of bone of bilateral lower limbs
  • Primary malignant neoplasm of bone of right leg
  • Primary malignant neoplasm of bone of right lower limb
  • Primary osteosarcoma of bilateral legs
  • Primary osteosarcoma of bilateral lower limbs
  • Primary osteosarcoma of right lower limb
ICD-10-CM C40.21 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 542 Pathological fractures and musculoskeletal and connective tissue malignancy with mcc
  • 543 Pathological fractures and musculoskeletal and connective tissue malignancy with cc
  • 544 Pathological fractures and musculoskeletal and connective tissue malignancy without cc/mcc

Convert C40.21 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
ICD-10-CM Codes Adjacent To C40.21
C40.0 Malignant neoplasm of scapula and long bones of upper limb
C40.00 Malignant neoplasm of scapula and long bones of unspecified upper limb
C40.01 Malignant neoplasm of scapula and long bones of right upper limb
C40.02 Malignant neoplasm of scapula and long bones of left upper limb
C40.1 Malignant neoplasm of short bones of upper limb
C40.10 Malignant neoplasm of short bones of unspecified upper limb
C40.11 Malignant neoplasm of short bones of right upper limb
C40.12 Malignant neoplasm of short bones of left upper limb
C40.2 Malignant neoplasm of long bones of lower limb
C40.20 Malignant neoplasm of long bones of unspecified lower limb
C40.21 Malignant neoplasm of long bones of right lower limb
C40.22 Malignant neoplasm of long bones of left lower limb
C40.3 Malignant neoplasm of short bones of lower limb
C40.30 Malignant neoplasm of short bones of unspecified lower limb
C40.31 Malignant neoplasm of short bones of right lower limb
C40.32 Malignant neoplasm of short bones of left lower limb
C40.8 Malignant neoplasm of overlapping sites of bone and articular cartilage of limb
C40.80 Malignant neoplasm of overlapping sites of bone and articular cartilage of unspecified limb
C40.81 Malignant neoplasm of overlapping sites of bone and articular cartilage of right limb
C40.82 Malignant neoplasm of overlapping sites of bone and articular cartilage of left limb
C40.9 Malignant neoplasm of unspecified bones and articular cartilage of limb

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.