Merkel cell carcinoma C4A- >

Clinical Information
  • A carcinoma arising from merkel cells located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of merkel cell carcinoma, occurring generally in elderly patients. (holland et al., cancer medicine, 3d ed, p1245)
  • A rare malignant cutaneous tumor seen in elderly patients. Its usual location is on the head, neck and extremities. The tumor is composed of small round cells with scanty cytoplasm arranged in a trabecular pattern, or in ill-defined nodules or in a diffuse pattern. The tumor cells contain cytoplasmic membrane-bound dense core granules resembling neurosecretory granules.
  • A rare type of cancer that forms on or just beneath the skin, usually in parts of the body that have been exposed to the sun. It is most common in older people and in people with weakened immune systems.
Codes
  • C4A Merkel cell carcinoma
    • C4A.0 Merkel cell carcinoma of lip
    • C4A.1 Merkel cell carcinoma of eyelid, including canthus
      • C4A.10 Merkel cell carcinoma of unspecified eyelid, including canthus
      • C4A.11 Merkel cell carcinoma of right eyelid, including canthus
        • C4A.111 Merkel cell carcinoma of right upper eyelid, including canthus
        • C4A.112 Merkel cell carcinoma of right lower eyelid, including canthus
      • C4A.12 Merkel cell carcinoma of left eyelid, including canthus
        • C4A.121 Merkel cell carcinoma of left upper eyelid, including canthus
        • C4A.122 Merkel cell carcinoma of left lower eyelid, including canthus
    • C4A.2 Merkel cell carcinoma of ear and external auricular canal
      • C4A.20 Merkel cell carcinoma of unspecified ear and external auricular canal
      • C4A.21 Merkel cell carcinoma of right ear and external auricular canal
      • C4A.22 Merkel cell carcinoma of left ear and external auricular canal
    • C4A.3 Merkel cell carcinoma of other and unspecified parts of face
      • C4A.30 Merkel cell carcinoma of unspecified part of face
      • C4A.31 Merkel cell carcinoma of nose
      • C4A.39 Merkel cell carcinoma of other parts of face
    • C4A.4 Merkel cell carcinoma of scalp and neck
    • C4A.5 Merkel cell carcinoma of trunk
      • C4A.51 Merkel cell carcinoma of anal skin
      • C4A.52 Merkel cell carcinoma of skin of breast
      • C4A.59 Merkel cell carcinoma of other part of trunk
    • C4A.6 Merkel cell carcinoma of upper limb, including shoulder
      • C4A.60 Merkel cell carcinoma of unspecified upper limb, including shoulder
      • C4A.61 Merkel cell carcinoma of right upper limb, including shoulder
      • C4A.62 Merkel cell carcinoma of left upper limb, including shoulder
    • C4A.7 Merkel cell carcinoma of lower limb, including hip
      • C4A.70 Merkel cell carcinoma of unspecified lower limb, including hip
      • C4A.71 Merkel cell carcinoma of right lower limb, including hip
      • C4A.72 Merkel cell carcinoma of left lower limb, including hip
    • C4A.8 Merkel cell carcinoma of overlapping sites
    • C4A.9 Merkel cell carcinoma, unspecified