1. ICD-10-CM Codes
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2. C00-D49
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3. C45-C49
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4. C45-
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5. 2023 ICD-10-CM Diagnosis Code C45

2023 ICD-10-CM Diagnosis Code C45

Mesothelioma

2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

• C45 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
• The 2023 edition of ICD-10-CM C45 became effective on October 1, 2022.
• This is the American ICD-10-CM version of C45 - other international versions of ICD-10 C45 may differ.

• A benign (noncancerous) or malignant (cancerous) tumor affecting the lining of the chest or abdomen. Exposure to asbestos particles in the air increases the risk of developing malignant mesothelioma.
• A benign or malignant tumor affecting the lining of the chest or abdomen
• A neoplasm originating from mesothelial cells of the pleura or peritoneum, for which the malignancy status has not been established.
• A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
• A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.
• Malignant tumor derived from mesothelial tissues of peritoneum, pleura, and pericardium.
• The tissue that lines your lungs, stomach, heart and other organs is called mesothelium. Mesothelioma is cancer of that tissue. It is a rare but serious type of cancer. It usually starts in the lungs, but can also start in the abdomen or other organs. Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles. It can take a long time - 30 to 50 years - between being around asbestos and getting the disease. Treatment includes surgery, radiation, chemotherapy or all three. nih: national cancer institute

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change

• Type 1 Excludes: C38
  , C48
  ICD-10-CM Diagnosis Code C38

  Malignant neoplasm of heart, mediastinum and pleura

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Type 1 Excludes

  • mesothelioma (C45.-)
  ICD-10-CM Diagnosis Code C48

  Malignant neoplasm of retroperitoneum and peritoneum

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Type 1 Excludes

  • Kaposi's sarcoma of connective tissue (C46.1)
  • mesothelioma (C45.-)
• Type 2 Excludes: C49
  ICD-10-CM Diagnosis Code C49

  Malignant neoplasm of other connective and soft tissue

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Includes

  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia
  • malignant neoplasm of fat
  • malignant neoplasm of ligament, except uterine
  • malignant neoplasm of lymphatic vessel
  • malignant neoplasm of muscle
  • malignant neoplasm of synovia
  • malignant neoplasm of tendon (sheath)

  Type 1 Excludes

  • malignant neoplasm of cartilage (of):
  • articular (C40-C41)
  • larynx (C32.3)
  • nose (C30.0)
  • malignant neoplasm of connective tissue of breast (C50.-)

  Type 2 Excludes

  • Kaposi's sarcoma of soft tissue (C46.1)
  • malignant neoplasm of heart (C38.0)
  • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
  • malignant neoplasm of peritoneum (C48.2)
  • malignant neoplasm of retroperitoneum (C48.0)
  • malignant neoplasm of uterine ligament (C57.3)
  • mesothelioma (C45.-)

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.