2023 ICD-10-CM Diagnosis Code C45.2

Mesothelioma of pericardium

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • C45.2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM C45.2 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of C45.2 - other international versions of ICD-10 C45.2 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as C45.2. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • other malignant neoplasm of pericardium (
    ICD-10-CM Diagnosis Code C38.0

    Malignant neoplasm of heart

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Malignant neoplasm of pericardium
    Type 1 Excludes
    • malignant neoplasm of great vessels (C49.3)
    C38.0
    )
The following code(s) above C45.2 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C45.2:
  • C00-D49
    2023 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
Approximate Synonyms
  • Malignant mesothelioma of pericardium
  • Malignant mesothelioma, pericardium
Clinical Information
  • This is a rare tumor. Approximately 100 to 150 cases have been reported in the literature. In most cases the diagnosis is made at autopsy or postoperatively. Clinical signs and symptoms include: pericardial effusion, congestive heart failure, a mass or tamponade. The prognosis for pericardial mesothelioma is extremely poor due to its late presentation and difficulty in completely removing it surgically. Surgical resection remains the treatment of choice. Addition of chemotherapy or radiation have been disappointing.
ICD-10-CM C45.2 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 314 Other circulatory system diagnoses with mcc
  • 315 Other circulatory system diagnoses with cc
  • 316 Other circulatory system diagnoses without cc/mcc

Convert C45.2 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to C45.2:
  • Mesothelioma (malignant) C45.9
    ICD-10-CM Diagnosis Code C45.9

    Mesothelioma, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

ICD-10-CM Codes Adjacent To C45.2
C44.82 Squamous cell carcinoma of overlapping sites of skin
C44.89 Other specified malignant neoplasm of overlapping sites of skin
C44.9 Other and unspecified malignant neoplasm of skin, unspecified
C44.90 Unspecified malignant neoplasm of skin, unspecified
C44.91 Basal cell carcinoma of skin, unspecified
C44.92 Squamous cell carcinoma of skin, unspecified
C44.99 Other specified malignant neoplasm of skin, unspecified
C45 Mesothelioma
C45.0 Mesothelioma of pleura
C45.1 Mesothelioma of peritoneum
C45.2 Mesothelioma of pericardium
C45.7 Mesothelioma of other sites
C45.9 Mesothelioma, unspecified
C46 Kaposi's sarcoma
C46.0 Kaposi's sarcoma of skin
C46.1 Kaposi's sarcoma of soft tissue
C46.2 Kaposi's sarcoma of palate
C46.3 Kaposi's sarcoma of lymph nodes
C46.4 Kaposi's sarcoma of gastrointestinal sites
C46.5 Kaposi's sarcoma of lung
C46.50 Kaposi's sarcoma of unspecified lung

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.