1. ICD-10-CM Codes
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2. C00-D49
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3. C45-C49
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4. C49-
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5. 2023 ICD-10-CM Diagnosis Code C49

2023 ICD-10-CM Diagnosis Code C49

Malignant neoplasm of other connective and soft tissue

2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

• C49 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
• The 2023 edition of ICD-10-CM C49 became effective on October 1, 2022.
• This is the American ICD-10-CM version of C49 - other international versions of ICD-10 C49 may differ.

• A malignant neoplasm affecting the skeletal or smooth muscles. Malignant neoplasms arising from the skeletal muscles are called rhabdomyosarcomas. Malignant neoplasms arising from the smooth muscles are called leiomyosarcomas.
• A malignant neoplasm arising from the blood vessels.

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change

• Code First: M63
  ICD-10-CM Diagnosis Code M63

  Disorders of muscle in diseases classified elsewhere

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Code First

  • underlying disease, such as:
  • leprosy (A30.-)
  • neoplasm (C49.-, C79.89, D21.-, D48.1)
  • schistosomiasis (B65.-)
  • trichinellosis (B75)

  Type 1 Excludes

  • myopathy in cysticercosis (B69.81)
  • myopathy in endocrine diseases (G73.7)
  • myopathy in metabolic diseases (G73.7)
  • myopathy in sarcoidosis (D86.87)
  • myopathy in secondary syphilis (A51.49)
  • myopathy in syphilis (late) (A52.78)
  • myopathy in toxoplasmosis (B58.82)
  • myopathy in tuberculosis (A18.09)

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.