ICD-10-CM Codes
C00-D49 Neoplasms
C45-C49 Malignant neoplasms of mesothelial and soft tissue
C49- Malignant neoplasm of other connective and soft tissue

2019 ICD-10-CM Diagnosis Code C49.0

Malignant neoplasm of connective and soft tissue of head, face and neck

2016

2017

2018

2019

Billable/Specific Code

C49.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
Short description: Malig neoplm of conn and soft tissue of head, face and neck
The 2019 edition of ICD-10-CM C49.0 became effective on October 1, 2018.
This is the American ICD-10-CM version of C49.0 - other international versions of ICD-10 C49.0 may differ.

Applicable To

Malignant neoplasm of connective tissue of ear
Malignant neoplasm of connective tissue of eyelid

Type 1 Excludes

Type 1 Excludes Help

A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as C49.0. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

connective tissue of orbit (
ICD-10-CM Diagnosis Code C69.6
Malignant neoplasm of orbit
Applicable To
- Malignant neoplasm of connective tissue of orbit
- Malignant neoplasm of extraocular muscle
- Malignant neoplasm of peripheral nerves of orbit
- Malignant neoplasm of retrobulbar tissue
- Malignant neoplasm of retro-ocular tissue
Type 1 Excludes
- malignant neoplasm of orbital bone (C41.0)
C69.6-
)

The following code(s) above C49.0 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to C49.0:

C00-D49
2019 ICD-10-CM Range C00-D49
Neoplasms
Note
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
Neoplasms
C49
ICD-10-CM Diagnosis Code C49
Malignant neoplasm of other connective and soft tissue
Includes
- malignant neoplasm of blood vessel
- malignant neoplasm of bursa
- malignant neoplasm of cartilage
- malignant neoplasm of fascia
- malignant neoplasm of fat
- malignant neoplasm of ligament, except uterine
- malignant neoplasm of lymphatic vessel
- malignant neoplasm of muscle
- malignant neoplasm of synovia
- malignant neoplasm of tendon (sheath)
Type 1 Excludes
- malignant neoplasm of cartilage (of):
- articular (C40-C41)
- larynx (C32.3)
- nose (C30.0)
- malignant neoplasm of connective tissue of breast (C50.-)
Type 2 Excludes
- Kaposi's sarcoma of soft tissue (C46.1)
- malignant neoplasm of heart (C38.0)
- malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
- malignant neoplasm of peritoneum (C48.2)
- malignant neoplasm of retroperitoneum (C48.0)
- malignant neoplasm of uterine ligament (C57.3)
- mesothelioma (C45.-)
Malignant neoplasm of other connective and soft tissue

Approximate Synonyms

Angiosarcoma, face
Angiosarcoma, head
Angiosarcoma, neck
Atypical fibroxanthoma of skin of neck
Atypical fibroxanthoma of skin of scalp
Cancer of the blood vessel, face
Cancer of the blood vessel, head
Cancer of the blood vessel, neck
Cancer of the muscle, face
Cancer of the muscle, head
Cancer of the muscle, neck
Cancer of the soft tissue, face
Cancer of the soft tissue, head
Cancer of the soft tissue, neck
Cancer of the tongue, sarcoma
Fibroxanthoma of neck, atypical
Fibroxanthoma of scalp, atypical
Leiomyosarcoma, face
Leiomyosarcoma, head
Leiomyosarcoma, neck
Liposarcoma, face
Liposarcoma, head
Liposarcoma, neck
Malignant fibrous histiocytoma, face
Malignant fibrous histiocytoma, head
Malignant fibrous histiocytoma, neck
Primary angiosarcoma of face
Primary angiosarcoma of head
Primary angiosarcoma of neck
Primary leiomyosarcoma of face
Primary leiomyosarcoma of head
Primary leiomyosarcoma of neck
Primary liposarcoma of face
Primary liposarcoma of head
Primary liposarcoma of neck
Primary malignant fibrous histiocytoma of face
Primary malignant fibrous histiocytoma of head
Primary malignant fibrous histiocytoma of neck
Primary malignant neoplasm of blood vessel of face
Primary malignant neoplasm of blood vessel of head
Primary malignant neoplasm of blood vessel of neck
Primary malignant neoplasm of muscle of face
Primary malignant neoplasm of muscle of head
Primary malignant neoplasm of muscle of neck
Primary malignant neoplasm of soft tissues of face
Primary malignant neoplasm of soft tissues of head
Primary malignant neoplasm of soft tissues of neck
Primary rhabdomyosarcoma of face
Primary rhabdomyosarcoma of head
Primary rhabdomyosarcoma of neck
Primary sarcoma of tongue
Rhabdomyosarcoma, face
Rhabdomyosarcoma, head
Rhabdomyosarcoma, neck
Sarcoma of face
Sarcoma of head
Sarcoma of neck
Sarcoma, face
Sarcoma, head
Sarcoma, neck

ICD-10-CM C49.0 is grouped within Diagnostic Related Group(s) (MS-DRG v36.0):

542 Pathological fractures and musculoskeletal and connective tissue malignancy with mcc
543 Pathological fractures and musculoskeletal and connective tissue malignancy with cc
544 Pathological fractures and musculoskeletal and connective tissue malignancy without cc/mcc

Convert C49.0 to ICD-9-CM

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change

Code annotations containing back-references to C49.0:

Type 1 Excludes: C30.1
, C41
, C41
, C44.1
, C44.2
, C69

ICD-10-CM Diagnosis Code C30.1
Malignant neoplasm of middle ear
Applicable To
- Malignant neoplasm of antrum tympanicum
- Malignant neoplasm of auditory tube
- Malignant neoplasm of eustachian tube
- Malignant neoplasm of inner ear
- Malignant neoplasm of mastoid air cells
- Malignant neoplasm of tympanic cavity
Type 1 Excludes
- malignant neoplasm of auricular canal (external) (C43.2-,C44.2-)
- malignant neoplasm of bone of ear (meatus) (C41.0)
- malignant neoplasm of cartilage of ear (C49.0)
- malignant melanoma of skin of (external) ear (C43.2-)
- other and unspecified malignant neoplasm of skin of (external) ear (C44.2-)
ICD-10-CM Diagnosis Code C41
Malignant neoplasm of bone and articular cartilage of other and unspecified sites
Type 1 Excludes
- malignant neoplasm of bones of limbs (C40.-)
- malignant neoplasm of cartilage of ear (C49.0)
- malignant neoplasm of cartilage of eyelid (C49.0)
- malignant neoplasm of cartilage of larynx (C32.3)
- malignant neoplasm of cartilage of limbs (C40.-)
- malignant neoplasm of cartilage of nose (C30.0)
ICD-10-CM Diagnosis Code C41
Malignant neoplasm of bone and articular cartilage of other and unspecified sites
Type 1 Excludes
- malignant neoplasm of bones of limbs (C40.-)
- malignant neoplasm of cartilage of ear (C49.0)
- malignant neoplasm of cartilage of eyelid (C49.0)
- malignant neoplasm of cartilage of larynx (C32.3)
- malignant neoplasm of cartilage of limbs (C40.-)
- malignant neoplasm of cartilage of nose (C30.0)
ICD-10-CM Diagnosis Code C44.1
Other and unspecified malignant neoplasm of skin of eyelid, including canthus
Type 1 Excludes
- connective tissue of eyelid (C49.0)
ICD-10-CM Diagnosis Code C44.2
Other and unspecified malignant neoplasm of skin of ear and external auricular canal
Type 1 Excludes
- connective tissue of ear (C49.0)
ICD-10-CM Diagnosis Code C69
Malignant neoplasm of eye and adnexa
Type 1 Excludes
- malignant neoplasm of connective tissue of eyelid (C49.0)
- malignant neoplasm of eyelid (skin) (C43.1-, C44.1-)
- malignant neoplasm of optic nerve (C72.3-)

ICD-10-CM Codes Adjacent To C49.0

C47.5 Malignant neoplasm of peripheral nerves of pelvis

C47.6 Malignant neoplasm of peripheral nerves of trunk, unspecified

C47.8 Malignant neoplasm of overlapping sites of peripheral nerves and autonomic nervous system

C47.9 Malignant neoplasm of peripheral nerves and autonomic nervous system, unspecified

C48 Malignant neoplasm of retroperitoneum and peritoneum

C48.0 Malignant neoplasm of retroperitoneum

C48.1 Malignant neoplasm of specified parts of peritoneum

C48.2 Malignant neoplasm of peritoneum, unspecified

C48.8 Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum

C49 Malignant neoplasm of other connective and soft tissue

C49.0 Malignant neoplasm of connective and soft tissue of head, face and neck

C49.1 Malignant neoplasm of connective and soft tissue of upper limb, including shoulder

C49.10 Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder

C49.11 Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder

C49.12 Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder

C49.2 Malignant neoplasm of connective and soft tissue of lower limb, including hip

C49.20 Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip

C49.21 Malignant neoplasm of connective and soft tissue of right lower limb, including hip

C49.22 Malignant neoplasm of connective and soft tissue of left lower limb, including hip

C49.3 Malignant neoplasm of connective and soft tissue of thorax

C49.4 Malignant neoplasm of connective and soft tissue of abdomen

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2019 ICD-10-CM Diagnosis Code C49.0

Malignant neoplasm of connective and soft tissue of head, face and neck

Malignant neoplasm of orbit

Neoplasms

Malignant neoplasm of other connective and soft tissue

Malignant neoplasm of middle ear

Malignant neoplasm of bone and articular cartilage of other and unspecified sites

Malignant neoplasm of bone and articular cartilage of other and unspecified sites

Other and unspecified malignant neoplasm of skin of eyelid, including canthus

Other and unspecified malignant neoplasm of skin of ear and external auricular canal

Malignant neoplasm of eye and adnexa