2023 ICD-10-CM Diagnosis Code C49.22

Malignant neoplasm of connective and soft tissue of left lower limb, including hip

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • C49.22 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Malig neoplm of conn and soft tiss of left low limb, inc hip
  • The 2023 edition of ICD-10-CM C49.22 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of C49.22 - other international versions of ICD-10 C49.22 may differ.
The following code(s) above C49.22 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C49.22:
  • C00-D49
    2023 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C49
    ICD-10-CM Diagnosis Code C49

    Malignant neoplasm of other connective and soft tissue

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Includes
    • malignant neoplasm of blood vessel
    • malignant neoplasm of bursa
    • malignant neoplasm of cartilage
    • malignant neoplasm of fascia
    • malignant neoplasm of fat
    • malignant neoplasm of ligament, except uterine
    • malignant neoplasm of lymphatic vessel
    • malignant neoplasm of muscle
    • malignant neoplasm of synovia
    • malignant neoplasm of tendon (sheath)
    Type 1 Excludes
    • malignant neoplasm of cartilage (of):
    • articular (C40-C41)
    • larynx (C32.3)
    • nose (C30.0)
    • malignant neoplasm of connective tissue of breast (C50.-)
    Type 2 Excludes
    • Kaposi's sarcoma of soft tissue (C46.1)
    • malignant neoplasm of heart (C38.0)
    • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
    • malignant neoplasm of peritoneum (C48.2)
    • malignant neoplasm of retroperitoneum (C48.0)
    • malignant neoplasm of uterine ligament (C57.3)
    • mesothelioma (C45.-)
    Malignant neoplasm of other connective and soft tissue
Approximate Synonyms
  • Angiosarcoma, bilateral hips
  • Angiosarcoma, bilateral legs
  • Angiosarcoma, l hip
  • Angiosarcoma, l leg
  • Cancer, soft tissue of left leg
  • Leiomyosarcoma, bilateral hips
  • Leiomyosarcoma, bilateral legs
  • Leiomyosarcoma, l hip
  • Leiomyosarcoma, l leg
  • Liposarcoma, bilateral hips
  • Liposarcoma, bilateral legs
  • Liposarcoma, l hip
  • Liposarcoma, l leg
  • Malignant fibrous histiocytoma, bilateral hips
  • Malignant fibrous histiocytoma, bilateral legs
  • Malignant fibrous histiocytoma, l hip
  • Malignant fibrous histiocytoma, l leg
  • Muscle cancer, bilateral hips
  • Muscle cancer, bilateral legs
  • Muscle cancer, l hip
  • Muscle cancer, l leg
  • Primary angiosarcoma of bilateral hips
  • Primary angiosarcoma of bilateral lower limbs
  • Primary angiosarcoma of left hip
  • Primary angiosarcoma of left lower limb
  • Primary leiomyosarcoma of bilateral hips
  • Primary leiomyosarcoma of bilateral lower limbs
  • Primary leiomyosarcoma of left hip
  • Primary leiomyosarcoma of left lower limb
  • Primary liposarcoma of bilateral hips
  • Primary liposarcoma of bilateral lower limbs
  • Primary liposarcoma of left hip
  • Primary liposarcoma of left lower limb
  • Primary malignant fibrous histiocytoma of bilateral hips
  • Primary malignant fibrous histiocytoma of bilateral lower limbs
  • Primary malignant fibrous histiocytoma of left hip
  • Primary malignant fibrous histiocytoma of left lower limb
  • Primary malignant neoplasm of muscle of bilateral hips
  • Primary malignant neoplasm of muscle of bilateral lower limbs
  • Primary malignant neoplasm of muscle of left hip
  • Primary malignant neoplasm of muscle of left lower limb
  • Primary malignant neoplasm of soft tissue of bilateral hips
  • Primary malignant neoplasm of soft tissue of bilateral lower limbs
  • Primary malignant neoplasm of soft tissue of left leg
  • Primary malignant neoplasm of soft tissue of left lower limb
  • Primary malignant neoplasm of soft tissues of left hip
  • Primary rhabdomyosarcoma of bilateral hips
  • Primary rhabdomyosarcoma of bilateral lower limbs
  • Primary rhabdomyosarcoma of left hip
  • Primary rhabdomyosarcoma of left lower limb
  • Primary sarcoma of bilateral hips
  • Primary sarcoma of bilateral lower limbs
  • Primary sarcoma of left hip
  • Primary sarcoma of left lower limb
  • Rhabdomyosarcoma, bilateral hips
  • Rhabdomyosarcoma, bilateral legs
  • Rhabdomyosarcoma, l hip
  • Rhabdomyosarcoma, l leg
  • Sarcoma, bilateral hips
  • Sarcoma, bilateral legs
  • Sarcoma, l hip
  • Sarcoma, l leg
  • Soft tissue cancer, bilateral hips
  • Soft tissue cancer, bilateral legs
  • Soft tissue cancer, l hip
ICD-10-CM C49.22 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 542 Pathological fractures and musculoskeletal and connective tissue malignancy with mcc
  • 543 Pathological fractures and musculoskeletal and connective tissue malignancy with cc
  • 544 Pathological fractures and musculoskeletal and connective tissue malignancy without cc/mcc

Convert C49.22 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
ICD-10-CM Codes Adjacent To C49.22
C48.8 Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum
C49 Malignant neoplasm of other connective and soft tissue
C49.0 Malignant neoplasm of connective and soft tissue of head, face and neck
C49.1 Malignant neoplasm of connective and soft tissue of upper limb, including shoulder
C49.10 Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder
C49.11 Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder
C49.12 Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder
C49.2 Malignant neoplasm of connective and soft tissue of lower limb, including hip
C49.20 Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip
C49.21 Malignant neoplasm of connective and soft tissue of right lower limb, including hip
C49.22 Malignant neoplasm of connective and soft tissue of left lower limb, including hip
C49.3 Malignant neoplasm of connective and soft tissue of thorax
C49.4 Malignant neoplasm of connective and soft tissue of abdomen
C49.5 Malignant neoplasm of connective and soft tissue of pelvis
C49.6 Malignant neoplasm of connective and soft tissue of trunk, unspecified
C49.8 Malignant neoplasm of overlapping sites of connective and soft tissue
C49.9 Malignant neoplasm of connective and soft tissue, unspecified
C49.A Gastrointestinal stromal tumor
C49.A0 …… unspecified site
C49.A1 …… of esophagus
C49.A2 …… of stomach

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.