2022

  1. ICD-10-CM Codes
    2. ›
  2. C00-D49 Neoplasms
    3. ›
  3. C45-C49 Malignant neoplasms of mesothelial and soft tissue
    4. ›
  4. C49- Malignant neoplasm of other connective and soft tissue
    5. ›
  5. 2022 ICD-10-CM Diagnosis Code C49.9

2022 ICD-10-CM Diagnosis Code C49.9

Malignant neoplasm of connective and soft tissue, unspecified

    2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
  • C49.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Malignant neoplasm of connective and soft tissue, unsp
  • The 2022 edition of ICD-10-CM C49.9 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of C49.9 - other international versions of ICD-10 C49.9 may differ.
The following code(s) above C49.9 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C49.9:
  • C00-D49
    2022 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C49
    ICD-10-CM Diagnosis Code C49

    Malignant neoplasm of other connective and soft tissue

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Includes
    • malignant neoplasm of blood vessel
    • malignant neoplasm of bursa
    • malignant neoplasm of cartilage
    • malignant neoplasm of fascia
    • malignant neoplasm of fat
    • malignant neoplasm of ligament, except uterine
    • malignant neoplasm of lymphatic vessel
    • malignant neoplasm of muscle
    • malignant neoplasm of synovia
    • malignant neoplasm of tendon (sheath)
    Type 1 Excludes
    • malignant neoplasm of cartilage (of):
    • articular (C40-C41)
    • larynx (C32.3)
    • nose (C30.0)
    • malignant neoplasm of connective tissue of breast (C50.-)
    Type 2 Excludes
    • Kaposi's sarcoma of soft tissue (C46.1)
    • malignant neoplasm of heart (C38.0)
    • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
    • malignant neoplasm of peritoneum (C48.2)
    • malignant neoplasm of retroperitoneum (C48.0)
    • malignant neoplasm of uterine ligament (C57.3)
    • mesothelioma (C45.-)
    Malignant neoplasm of other connective and soft tissue
Approximate Synonyms
  • Angiosarcoma
  • Atypical fibroxanthoma of skin
  • Atypical fibroxanthoma, skin
  • Cancer of the soft tissue
  • Cancer of the synovium, sarcoma
  • Cancer, angiosarcoma
  • Cancer, leiomyosarcoma
  • Cancer, liposarcoma
  • Cancer, malignant fibrous histiocytoma
  • Cancer, myxoid liposarcoma
  • Cancer, rhabdomyosarcoma
  • Cancer, sarcoma
  • Ganglioneuroblastoma
  • Leiomyosarcoma
  • Liposarcoma
  • Malignant fibrous histiocytoma
  • Malignant neoplasm of soft tissue
  • Myxoid liposarcoma
  • Rhabdomyosarcoma
  • Sarcoma
  • Sarcoma of soft tissue
  • Sarcoma, soft tissue
  • Synovial sarcoma
ICD-10-CM C49.9 is grouped within Diagnostic Related Group(s) (MS-DRG v39.0):
  • 542 Pathological fractures and musculoskeletal and connective tissue malignancy with mcc
  • 543 Pathological fractures and musculoskeletal and connective tissue malignancy with cc
  • 544 Pathological fractures and musculoskeletal and connective tissue malignancy without cc/mcc

Convert C49.9 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
ICD-10-CM Codes Adjacent To C49.9
C49.12 Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder
C49.2 Malignant neoplasm of connective and soft tissue of lower limb, including hip
C49.20 Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip
C49.21 Malignant neoplasm of connective and soft tissue of right lower limb, including hip
C49.22 Malignant neoplasm of connective and soft tissue of left lower limb, including hip
C49.3 Malignant neoplasm of connective and soft tissue of thorax
C49.4 Malignant neoplasm of connective and soft tissue of abdomen
C49.5 Malignant neoplasm of connective and soft tissue of pelvis
C49.6 Malignant neoplasm of connective and soft tissue of trunk, unspecified
C49.8 Malignant neoplasm of overlapping sites of connective and soft tissue
C49.9 Malignant neoplasm of connective and soft tissue, unspecified
C49.A Gastrointestinal stromal tumor
C49.A0 …… unspecified site
C49.A1 …… of esophagus
C49.A2 …… of stomach
C49.A3 …… of small intestine
C49.A4 …… of large intestine
C49.A5 …… of rectum
C49.A9 …… of other sites
C50 Malignant neoplasm of breast
C50.0 Malignant neoplasm of nipple and areola

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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