2023 ICD-10-CM Diagnosis Code C49.A4

Gastrointestinal stromal tumor of large intestine

    2017 - New Code 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • C49.A4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM C49.A4 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of C49.A4 - other international versions of ICD-10 C49.A4 may differ.
The following code(s) above C49.A4 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C49.A4:
  • C00-D49
    2023 ICD-10-CM Range C00-D49


    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
  • C49
    ICD-10-CM Diagnosis Code C49

    Malignant neoplasm of other connective and soft tissue

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    • malignant neoplasm of blood vessel
    • malignant neoplasm of bursa
    • malignant neoplasm of cartilage
    • malignant neoplasm of fascia
    • malignant neoplasm of fat
    • malignant neoplasm of ligament, except uterine
    • malignant neoplasm of lymphatic vessel
    • malignant neoplasm of muscle
    • malignant neoplasm of synovia
    • malignant neoplasm of tendon (sheath)
    Type 1 Excludes
    • malignant neoplasm of cartilage (of):
    • articular (C40-C41)
    • larynx (C32.3)
    • nose (C30.0)
    • malignant neoplasm of connective tissue of breast (C50.-)
    Type 2 Excludes
    • Kaposi's sarcoma of soft tissue (C46.1)
    • malignant neoplasm of heart (C38.0)
    • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
    • malignant neoplasm of peritoneum (C48.2)
    • malignant neoplasm of retroperitoneum (C48.0)
    • malignant neoplasm of uterine ligament (C57.3)
    • mesothelioma (C45.-)
    Malignant neoplasm of other connective and soft tissue
ICD-10-CM C49.A4 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 374 Digestive malignancy with mcc
  • 375 Digestive malignancy with cc
  • 376 Digestive malignancy without cc/mcc

Convert C49.A4 to ICD-9-CM

Code History
  • 2017 (effective 10/1/2016): New code
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to C49.A4:

ICD-10-CM Codes Adjacent To C49.A4
C49.4 Malignant neoplasm of connective and soft tissue of abdomen
C49.5 Malignant neoplasm of connective and soft tissue of pelvis
C49.6 Malignant neoplasm of connective and soft tissue of trunk, unspecified
C49.8 Malignant neoplasm of overlapping sites of connective and soft tissue
C49.9 Malignant neoplasm of connective and soft tissue, unspecified
C49.A Gastrointestinal stromal tumor
C49.A0 …… unspecified site
C49.A1 …… of esophagus
C49.A2 …… of stomach
C49.A3 …… of small intestine
C49.A4 …… of large intestine
C49.A5 …… of rectum
C49.A9 …… of other sites
C50 Malignant neoplasm of breast
C50.0 Malignant neoplasm of nipple and areola
C50.01 Malignant neoplasm of nipple and areola, female
C50.011 Malignant neoplasm of nipple and areola, right female breast
C50.012 Malignant neoplasm of nipple and areola, left female breast
C50.019 Malignant neoplasm of nipple and areola, unspecified female breast
C50.02 Malignant neoplasm of nipple and areola, male
C50.021 Malignant neoplasm of nipple and areola, right male breast

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.