1. ICD-10-CM Codes
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2. C00-D49 Neoplasms
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3. C50-C50 Malignant neoplasms of breast
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4. C50- Malignant neoplasm of breast
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2020 ICD-10-CM Diagnosis Code C50

Malignant neoplasm of breast

2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code

• C50 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
• The 2020 edition of ICD-10-CM C50 became effective on October 1, 2019.
• This is the American ICD-10-CM version of C50 - other international versions of ICD-10 C50 may differ.

• A form of breast cancer in which the tumor grows from ducts beneath the nipple onto the surface of the nipple. Symptoms commonly include itching and burning and an eczema-like condition around the nipple, sometimes accompanied by oozing or bleeding.
• A malignant epithelial cellular proliferation characterized by the presence of atypical cells with large nuclei and abundant pale cytoplasm within the squamous epithelium of the nipple. In almost all cases there is an underlying intraductal breast carcinoma or intraductal and invasive carcinoma. The skin changes range from redness to eczematous appearance.
• A malignant neoplasm in which there is infiltration of the skin overlying the breast by neoplastic large cells with abundant pale cytoplasm and large nuclei with prominent nucleoli (paget cells). It is almost always associated with an intraductal or invasive ductal carcinoma of the breast. The clinical features include focal skin reddening, and eczema. Retraction of the nipple may sometimes occur.
• A primary or metastatic malignant neoplasm involving the breast. The vast majority of cases are carcinomas arising from the breast parenchyma or the nipple. Malignant breast neoplasms occur more frequently in females than in males.
• An intraductal carcinoma of the breast extending to involve the nipple and areola, characterized clinically by eczema-like inflammatory skin changes and histologically by infiltration of the dermis by malignant cells (paget's cells). (Dorland, 27th ed)
• Breast cancer affects one in eight women during their lives. Breast cancer kills more women in the United States than any cancer except lung cancer. No one knows why some women get breast cancer, but there are a number of risk factors. Risks that you cannot change include
  • age - the chance of getting breast cancer rises as a woman gets older
  • genes - there are two genes, brca1 and brca2, that greatly increase the risk. Women who have family members with breast or ovarian cancer may wish to be tested.
  • personal factors - beginning periods before age 12 or going through menopause after age 55
  other risks include being overweight, using hormone replacement therapy (also called menopausal hormone therapy), taking birth control pills, drinking alcohol, not having children or having your first child after age 35 or having dense breasts.symptoms of breast cancer may include a lump in the breast, a change in size or shape of the breast or discharge from a nipple. Breast self-exam and mammography can help find breast cancer early when it is most treatable. Treatment may consist of radiation, lumpectomy, mastectomy, chemotherapy and hormone therapy.men can have breast cancer, too, but the number of cases is small. nih: national cancer institute
• Carcinoma of the breast extending to involve the nipple and areola, characterized clinically by eczema-like inflammatory skin changes and histologically by infiltration of the dermis by malignant cells.

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change

• Code Also: D61.82
  ICD-10-CM Diagnosis Code D61.82

  Myelophthisis

  2016 2017 2018 2019 2020 Billable/Specific Code

  Applicable To

  • Leukoerythroblastic anemia
  • Myelophthisic anemia
  • Panmyelophthisis

  Code Also

  • the underlying disorder, such as:
  • malignant neoplasm of breast (C50.-)
  • tuberculosis (A15.-)

  Type 1 Excludes

  • idiopathic myelofibrosis (D47.1)
  • myelofibrosis NOS (D75.81)
  • myelofibrosis with myeloid metaplasia (D47.4)
  • primary myelofibrosis (D47.1)
  • secondary myelofibrosis (D75.81)
• Code First: Z17
  , Z79.81
  , D75.81
  ICD-10-CM Diagnosis Code Z17

  Estrogen receptor status

  2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code

  Code First

  • malignant neoplasm of breast (C50.-)
  ICD-10-CM Diagnosis Code Z79.81

  Long term (current) use of agents affecting estrogen receptors and estrogen levels

  2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code

  Code First

  • , if applicable:
  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of prostate (C61)

  Type 1 Excludes

  • hormone replacement therapy (Z79.890)

  Use Additional

  • code, if applicable, to identify:
  • estrogen receptor positive status (Z17.0)
  • family history of breast cancer (Z80.3)
  • genetic susceptibility to malignant neoplasm (cancer) (Z15.0-)
  • personal history of breast cancer (Z85.3)
  • personal history of prostate cancer (Z85.46)
  • postmenopausal status (Z78.0)
  ICD-10-CM Diagnosis Code D75.81

  Myelofibrosis

  2016 2017 2018 2019 2020 Billable/Specific Code Manifestation Code

  Applicable To

  • Myelofibrosis NOS
  • Secondary myelofibrosis NOS

  Code First

  • the underlying disorder, such as:
  • malignant neoplasm of breast (C50.-)

  Type 1 Excludes

  • acute myelofibrosis (C94.4-)
  • idiopathic myelofibrosis (D47.1)
  • leukoerythroblastic anemia (D61.82)
  • myelofibrosis with myeloid metaplasia (D47.4)
  • myelophthisic anemia (D61.82)
  • myelophthisis (D61.82)
  • primary myelofibrosis (D47.1)

  Use Additional

  • code, if applicable, for associated therapy-related myelodysplastic syndrome (D46.-)
• Type 1 Excludes: C49
  , C49.3
  , D05
  ICD-10-CM Diagnosis Code C49

  Malignant neoplasm of other connective and soft tissue

  2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code

  Includes

  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia
  • malignant neoplasm of fat
  • malignant neoplasm of ligament, except uterine
  • malignant neoplasm of lymphatic vessel
  • malignant neoplasm of muscle
  • malignant neoplasm of synovia
  • malignant neoplasm of tendon (sheath)

  Type 1 Excludes

  • malignant neoplasm of cartilage (of):
  • articular (C40-C41)
  • larynx (C32.3)
  • nose (C30.0)
  • malignant neoplasm of connective tissue of breast (C50.-)

  Type 2 Excludes

  • Kaposi's sarcoma of soft tissue (C46.1)
  • malignant neoplasm of heart (C38.0)
  • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
  • malignant neoplasm of peritoneum (C48.2)
  • malignant neoplasm of retroperitoneum (C48.0)
  • malignant neoplasm of uterine ligament (C57.3)
  • mesothelioma (C45.-)
  ICD-10-CM Diagnosis Code C49.3

  Malignant neoplasm of connective and soft tissue of thorax

  2016 2017 2018 2019 2020 Billable/Specific Code

  Applicable To

  • Malignant neoplasm of axilla
  • Malignant neoplasm of diaphragm
  • Malignant neoplasm of great vessels

  Type 1 Excludes

  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of heart (C38.0)
  • malignant neoplasm of mediastinum (C38.1-C38.3)
  • malignant neoplasm of thymus (C37)
  ICD-10-CM Diagnosis Code D05

  Carcinoma in situ of breast

  2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code

  Type 1 Excludes

  • carcinoma in situ of skin of breast (D04.5)
  • melanoma in situ of breast (skin) (D03.5)
  • Paget's disease of breast or nipple (C50.-)
• Applicable To: Z80.3
  , Z85.3
  ICD-10-CM Diagnosis Code Z80.3

  Family history of malignant neoplasm of breast

  2016 2017 2018 2019 2020 Billable/Specific Code POA Exempt

  Applicable To

  • Conditions classifiable to C50.-
  ICD-10-CM Diagnosis Code Z85.3

  Personal history of malignant neoplasm of breast

  2016 2017 2018 2019 2020 Billable/Specific Code POA Exempt

  Applicable To

  • Conditions classifiable to C50.-

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.