2023 ICD-10-CM Diagnosis Code C52

Malignant neoplasm of vagina

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Female Dx
  • C52 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM C52 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of C52 - other international versions of ICD-10 C52 may differ.
ICD-10-CM Coding Rules
  • C52 is applicable to female patients.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as C52. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • carcinoma in situ of vagina (
    ICD-10-CM Diagnosis Code D07.2

    Carcinoma in situ of vagina

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Female Dx
    Applicable To
    • Severe dysplasia of vagina
    • Vaginal intraepithelial neoplasia III [VAIN III]
    Type 1 Excludes
    • moderate dysplasia of vagina (N89.1)
    • vaginal intraepithelial neoplasia II [VIN II] (N89.1)
    D07.2
    )
The following code(s) above C52 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C52:
  • C00-D49
    2023 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C51-C58
    2023 ICD-10-CM Range C51-C58

    Malignant neoplasms of female genital organs

    Includes
    • malignant neoplasm of skin of female genital organs
    Malignant neoplasms of female genital organs
Approximate Synonyms
  • Cancer of the vagina, adenocarcinoma
  • Cancer of the vagina, primary
  • Cancer of the vagina, recurrent to primary site
  • Cancer of the vagina, squamous cell
  • Malignant melanoma of vagina
  • Melanoma, vagina
  • Primary adenocarcinoma of vagina
  • Primary malignant neoplasm of vagina
  • Recurrent primary malignant neoplasm of vagina
  • Squamous cell cancer of vagina
Clinical Information
  • A primary or metastatic malignant tumor involving the vagina. Representative examples include carcinomas and sarcomas.
  • Vaginal cancer is a rare type of cancer. It is more common in women 60 and older. You are also more likely to get it if you have a human papillomavirus (hpv) infection or if your mother took diethylstilbestrol (des) when she was pregnant. Doctors prescribed des in the 1950's to prevent miscarriages.it often doesn't have early symptoms. However, see your doctor if you notice
    • bleeding that is not your period
    • a vaginal lump
    • pelvic pain
    a pap test can find abnormal cells that may be cancer. Vaginal cancer can often be cured in its early stages. Treatment might include surgery, radiation and chemotherapy. nih: national cancer institute
ICD-10-CM C52 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 736 Uterine and adnexa procedures for ovarian or adnexal malignancy with mcc
  • 737 Uterine and adnexa procedures for ovarian or adnexal malignancy with cc
  • 738 Uterine and adnexa procedures for ovarian or adnexal malignancy without cc/mcc
  • 739 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy with mcc
  • 740 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy with cc
  • 741 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy without cc/mcc
  • 754 Malignancy, female reproductive system with mcc
  • 755 Malignancy, female reproductive system with cc
  • 756 Malignancy, female reproductive system without cc/mcc

Convert C52 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
ICD-10-CM Codes Adjacent To C52
C50.92 Malignant neoplasm of breast of unspecified site, male
C50.921 Malignant neoplasm of unspecified site of right male breast
C50.922 Malignant neoplasm of unspecified site of left male breast
C50.929 Malignant neoplasm of unspecified site of unspecified male breast
C51 Malignant neoplasm of vulva
C51.0 Malignant neoplasm of labium majus
C51.1 Malignant neoplasm of labium minus
C51.2 Malignant neoplasm of clitoris
C51.8 Malignant neoplasm of overlapping sites of vulva
C51.9 Malignant neoplasm of vulva, unspecified
C52 Malignant neoplasm of vagina
C53 Malignant neoplasm of cervix uteri
C53.0 Malignant neoplasm of endocervix
C53.1 Malignant neoplasm of exocervix
C53.8 Malignant neoplasm of overlapping sites of cervix uteri
C53.9 Malignant neoplasm of cervix uteri, unspecified
C54 Malignant neoplasm of corpus uteri
C54.0 Malignant neoplasm of isthmus uteri
C54.1 Malignant neoplasm of endometrium
C54.2 Malignant neoplasm of myometrium
C54.3 Malignant neoplasm of fundus uteri

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.