2022 ICD-10-CM Diagnosis Code C58

Malignant neoplasm of placenta

    2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Maternity Dx (12-55 years) Female Dx
  • C58 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2022 edition of ICD-10-CM C58 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of C58 - other international versions of ICD-10 C58 may differ.
ICD-10-CM Coding Rules
  • C58 is applicable to maternity patients aged 12 - 55 years inclusive.
  • C58 is applicable to female patients.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as C58. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • chorioadenoma (destruens) (
    ICD-10-CM Diagnosis Code D39.2

    Neoplasm of uncertain behavior of placenta

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Maternity Dx (12-55 years)
    Applicable To
    • Chorioadenoma destruens
    • Invasive hydatidiform mole
    • Malignant hydatidiform mole
    Type 1 Excludes
    • hydatidiform mole NOS (O01.9)
    D39.2
    )
  • hydatidiform mole NOS (
    ICD-10-CM Diagnosis Code O01.9

    Hydatidiform mole, unspecified

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Maternity Dx (12-55 years)
    Applicable To
    • Trophoblastic disease NOS
    • Vesicular mole NOS
    O01.9
    )
  • invasive hydatidiform mole (
    ICD-10-CM Diagnosis Code D39.2

    Neoplasm of uncertain behavior of placenta

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Maternity Dx (12-55 years)
    Applicable To
    • Chorioadenoma destruens
    • Invasive hydatidiform mole
    • Malignant hydatidiform mole
    Type 1 Excludes
    • hydatidiform mole NOS (O01.9)
    D39.2
    )
  • male choriocarcinoma NOS (
    ICD-10-CM Diagnosis Code C62.9

    Malignant neoplasm of testis, unspecified whether descended or undescended

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    C62.9-
    )
  • malignant hydatidiform mole (
    ICD-10-CM Diagnosis Code D39.2

    Neoplasm of uncertain behavior of placenta

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Maternity Dx (12-55 years)
    Applicable To
    • Chorioadenoma destruens
    • Invasive hydatidiform mole
    • Malignant hydatidiform mole
    Type 1 Excludes
    • hydatidiform mole NOS (O01.9)
    D39.2
    )
Includes
Includes Help
"Includes" further defines, or give examples of, the content of the code or category.
  • choriocarcinoma NOS
  • chorionepithelioma NOS
The following code(s) above C58 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C58:
  • C00-D49
    2022 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C51-C58
    2022 ICD-10-CM Range C51-C58

    Malignant neoplasms of female genital organs

    Includes
    • malignant neoplasm of skin of female genital organs
    Malignant neoplasms of female genital organs
Approximate Synonyms
  • Cancer of the placenta
  • Cancer of the placenta, choriocarcinoma
  • Choriocarcinoma
  • Female choriocarcinoma
  • Gestational choriocarcinoma
  • Gestational trophoblastic neoplasia
  • Primary malignant neoplasm of placenta
Clinical Information
  • A malignant metastatic form of trophoblastic tumors. Unlike the hydatidiform mole, choriocarcinoma contains no chorionic villi but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (trophoblasts). It is characterized by the large amounts of chorionic gonadotropin produced. Tissue origins can be determined by dna analyses: placental (fetal) origin or non-placental origin (choriocarcinoma, non-gestational).
  • A malignant neoplasm arising from decidua (placental) cells.
  • A malignant neoplasm arising from placental trophoblast cells. They generally arise in the uterus.
  • A malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta). Almost all choriocarcinomas form in the uterus after fertilization of an egg by a sperm, but a small number form in a testis or an ovary. Choriocarcinomas spread through the blood to other organs, especially the lungs. They are a type of gestational trophoblastic disease.
  • An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hcg) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected.
  • Malignant metastatic form of trophoblastic tumors, contains sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts; characterized by the large amounts of chorionic gonadotropin produced; tissue origins can be placental (fetal) or non-placental.
  • Malignant neoplasm originating in the placenta
ICD-10-CM C58 is grouped within Diagnostic Related Group(s) (MS-DRG v39.0):
  • 736 Uterine and adnexa procedures for ovarian or adnexal malignancy with mcc
  • 737 Uterine and adnexa procedures for ovarian or adnexal malignancy with cc
  • 738 Uterine and adnexa procedures for ovarian or adnexal malignancy without cc/mcc
  • 739 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy with mcc
  • 740 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy with cc
  • 741 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy without cc/mcc
  • 754 Malignancy, female reproductive system with mcc
  • 755 Malignancy, female reproductive system with cc
  • 756 Malignancy, female reproductive system without cc/mcc

Convert C58 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change

Diagnosis Index entries containing back-references to C58:

ICD-10-CM Codes Adjacent To C58
C57.12 Malignant neoplasm of left broad ligament
C57.2 Malignant neoplasm of round ligament
C57.20 Malignant neoplasm of unspecified round ligament
C57.21 Malignant neoplasm of right round ligament
C57.22 Malignant neoplasm of left round ligament
C57.3 Malignant neoplasm of parametrium
C57.4 Malignant neoplasm of uterine adnexa, unspecified
C57.7 Malignant neoplasm of other specified female genital organs
C57.8 Malignant neoplasm of overlapping sites of female genital organs
C57.9 Malignant neoplasm of female genital organ, unspecified
C58 Malignant neoplasm of placenta
C60 Malignant neoplasm of penis
C60.0 Malignant neoplasm of prepuce
C60.1 Malignant neoplasm of glans penis
C60.2 Malignant neoplasm of body of penis
C60.8 Malignant neoplasm of overlapping sites of penis
C60.9 Malignant neoplasm of penis, unspecified
C61 Malignant neoplasm of prostate
C62 Malignant neoplasm of testis
C62.0 Malignant neoplasm of undescended testis
C62.00 Malignant neoplasm of unspecified undescended testis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.