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ICD-10-CM Codes
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C00-D49
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C81-C96
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C84-
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2023 ICD-10-CM Diagnosis Code C84.6
2023 ICD-10-CM Diagnosis Code C84.6
Anaplastic large cell lymphoma, ALK-positive
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
- C84.6 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
- The 2023 edition of ICD-10-CM C84.6 became effective on October 1, 2022.
- This is the American ICD-10-CM version of C84.6 - other international versions of ICD-10 C84.6 may differ.
Applicable To- Anaplastic large cell lymphoma, CD30-positive
The following code(s) above
C84.6 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
C84.6:
- C00-D49
2023 ICD-10-CM Range C00-D49
NeoplasmsNote- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
- C81-C96
2023 ICD-10-CM Range C81-C96
Malignant neoplasms of lymphoid, hematopoietic and related tissueType 2 Excludes- Kaposi's sarcoma of lymph nodes (C46.3)
- secondary and unspecified neoplasm of lymph nodes (C77.-)
- secondary neoplasm of bone marrow (C79.52)
- secondary neoplasm of spleen (C78.89)
- C84
ICD-10-CM Diagnosis Code C84
Mature T/NK-cell lymphomas
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
Type 1 Excludes- personal history of non-Hodgkin lymphoma (Z85.72)
- A peripheral (mature) t-cell lymphoma, consisting of usually large anaplastic, cd30 positive cells. The majority of cases are positive for the anaplastic large cell lymphoma (alk) protein. The most frequently seen genetic alteration is a t(2;5) translocation. Majority of patients present with advanced disease. The most important prognostic indicator is alk positivity, which has been associated with a favorable prognosis. (who, 2001)
- A systemic, large-cell, non-hodgkin, malignant lymphoma characterized by cells with pleomorphic appearance and expressing the cd30 antigen. These so-called "hallmark" cells have lobulated and indented nuclei. This lymphoma is often mistaken for metastatic carcinoma and malignant histiocytosis.
- A t-cell peripheral lymphoma composed of usually large, pleomorphic, cd30 positive t-lymphocytes with abundant cytoplasm characterized by the presence of a translocation involving the alk gene and expression of alk fusion protein. Most patients present with peripheral and/or abdominal lymphadenopathy, and often have advanced disease and extranodal involvement.
- An aggressive (fast-growing) type of non-hodgkin lymphoma that is usually of the t-cell type. The cancer cells express a marker called cd30 or ki-1 on the surface, and may appear in the lymph nodes, skin, bones, soft tissues, lungs, or liver.
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- 2022 (effective 10/1/2021): No change
- 2023 (effective 10/1/2022): No change
Code annotations containing back-references to C84.6:
- Lymphoma (of) (malignant) C85.90
ICD-10-CM Diagnosis Code C85.90
Non-Hodgkin lymphoma, unspecified, unspecified site
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM Codes Adjacent To C84.6
C84.41 …… lymph nodes of head, face, and neck
C84.42 …… intrathoracic lymph nodes
C84.43 …… intra-abdominal lymph nodes
C84.44 …… lymph nodes of axilla and upper limb
C84.45 …… lymph nodes of inguinal region and lower limb
C84.46 …… intrapelvic lymph nodes
C84.48 …… lymph nodes of multiple sites
C84.49 …… extranodal and solid organ sites
C84.6
Anaplastic large cell lymphoma, ALK-positive
C84.61 …… lymph nodes of head, face, and neck
C84.62 …… intrathoracic lymph nodes
C84.63 …… intra-abdominal lymph nodes
C84.64 …… lymph nodes of axilla and upper limb
C84.65 …… lymph nodes of inguinal region and lower limb
C84.66 …… intrapelvic lymph nodes
C84.68 …… lymph nodes of multiple sites
C84.69 …… extranodal and solid organ sites
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
