2022 ICD-10-CM Diagnosis Code C85.9

Non-Hodgkin lymphoma, unspecified

    2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
  • C85.9 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2022 edition of ICD-10-CM C85.9 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of C85.9 - other international versions of ICD-10 C85.9 may differ.
Applicable To
  • Lymphoma NOS
  • Malignant lymphoma NOS
  • Non-Hodgkin lymphoma NOS
The following code(s) above C85.9 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C85.9:
  • C00-D49
    2022 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C81-C96
    2022 ICD-10-CM Range C81-C96

    Malignant neoplasms of lymphoid, hematopoietic and related tissue

    Type 2 Excludes
    • Kaposi's sarcoma of lymph nodes (C46.3)
    • secondary and unspecified neoplasm of lymph nodes (C77.-)
    • secondary neoplasm of bone marrow (C79.52)
    • secondary neoplasm of spleen (C78.89)
    Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C85
    ICD-10-CM Diagnosis Code C85

    Other specified and unspecified types of non-Hodgkin lymphoma

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • other specified types of T/NK-cell lymphoma (C86.-)
    • personal history of non-Hodgkin lymphoma (Z85.72)
    Other specified and unspecified types of non-Hodgkin lymphoma
Clinical Information
  • A general term for various neoplastic diseases of the lymphoid tissue.
  • A group of cancers of the lymphoid system, including acute lymphoblastic leukemia, b-cell lymphoma, burkitt's lymphoma, diffuse cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, lymphoblastic lymphoma, mantle cell lymphoma, mycosis fungoides, post-transplantation lymphoproliferative disorder, small non-cleaved cell lymphoma, and t-cell lymphoma.
  • A malignant (clonal) proliferation of b- lymphocytes or t- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes non-hodgkin lymphomas and hodgkin lymphomas.
  • A malignant neoplasm composed of lymphocytes of b- or t/nk-cell phenotype.
  • Any of a group of malignant tumors of lymphoid tissue that differ from hodgkin disease, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant reed-sternberg cells, a characteristic of hodgkin's disease.
  • Any of a large group of cancers of lymphocytes (white blood cells). Nhls can occur at any age and are often marked by lymph nodes that are larger than normal, fever, and weight loss. There are many different types of nhl. These types can be divided into aggressive (fast-growing) and indolent (slow-growing) types, and they can be formed from either b-cells or t-cells. B-cell nhls include burkitt lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma (cll/sll), diffuse large b-cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, precursor b-lymphoblastic lymphoma, and mantle cell lymphoma. T-cell nhls include mycosis fungoides, anaplastic large cell lymphoma, and precursor t-lymphoblastic lymphoma. Lymphomas that occur after bone marrow or stem cell transplantation are usually b-cell nhls. Prognosis and treatment depend on the stage and type of disease.
  • Cancer that begins in cells of the immune system. There are two basic categories of lymphomas. One kind is hodgkin lymphoma, which is marked by the presence of a type of cell called the reed-sternberg cell. The other category is non-hodgkin lymphomas, which includes a large, diverse group of cancers of immune system cells. Non-hodgkin lymphomas can be further divided into cancers that have an indolent (slow-growing) course and those that have an aggressive (fast-growing) course. These subtypes behave and respond to treatment differently. Both hodgkin and non-hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer.
  • Characterized by malignant lymphomas; clinically similar to hodgkin's disease, except that the lymphomas seen in this disease are initially more widespread; most common manifestation is painless enlargement of one or more peripheral lymph nodes.
  • Distinct from hodgkin lymphoma both morphologically and biologically, non-hodgkin lymphoma (nhl) is characterized by the absence of reed-sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. Nhl is clinically classified as indolent, aggressive, or having a variable clinical course. Nhl can be of b-or t-/nk-cell lineage.
  • Lymphoma is a cancer of a part of the immune system called the lymphatic system. There are many types of lymphoma. One type is called hodgkin disease. The rest are called non-hodgkin lymphoma. Non-hodgkin lymphomas begin when a type of white blood cell, called a t cell or b cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors can't determine why a person gets non-hodgkin lymphoma. Non-hodgkin lymphoma can cause many symptoms, such as
    • swollen, painless lymph nodes in the neck, armpits or groin
    • unexplained weight loss
    • fever
    • soaking night sweats
    • coughing, trouble breathing or chest pain
    • weakness and tiredness that don't go away
    • pain, swelling or a feeling of fullness in the abdomen
    your doctor will perform an exam and lab tests to determine if you have lymphoma. nih: national cancer institute
  • Malignant (clonal) proliferation of b- or t- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites; general term for various neoplastic diseases of the lymphoid tissue.
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
Code annotations containing back-references to C85.9:
  • Code First: N16
    ICD-10-CM Diagnosis Code N16

    Renal tubulo-interstitial disorders in diseases classified elsewhere

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Manifestation Code
    Applicable To
    • Pyelonephritis
    • Tubulo-interstitial nephritis
    Code First
    Type 1 Excludes
    • diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84)
    • pyelonephritis and tubulo-interstitial nephritis in candidiasis (B37.49)
    • pyelonephritis and tubulo-interstitial nephritis in cystinosis (E72.04)
    • pyelonephritis and tubulo-interstitial nephritis in salmonella infection (A02.25)
    • pyelonephritis and tubulo-interstitial nephritis in sarcoidosis (D86.84)
    • pyelonephritis and tubulo-interstitial nephritis in Sjogren syndrome (M35.04)
    • pyelonephritis and tubulo-interstitial nephritis in systemic lupus erythematosus (M32.15)
    • pyelonephritis and tubulo-interstitial nephritis in toxoplasmosis (B58.83)
    • renal tubular degeneration in diabetes (E08-E13 with .29)
    • syphilitic pyelonephritis and tubulo-interstitial nephritis (A52.75)

Diagnosis Index entries containing back-references to C85.9:

ICD-10-CM Codes Adjacent To C85.9
C85.80 …… unspecified site
C85.81 …… lymph nodes of head, face, and neck
C85.82 …… intrathoracic lymph nodes
C85.83 …… intra-abdominal lymph nodes
C85.84 …… lymph nodes of axilla and upper limb
C85.85 …… lymph nodes of inguinal region and lower limb
C85.86 …… intrapelvic lymph nodes
C85.87 …… spleen
C85.88 …… lymph nodes of multiple sites
C85.89 …… extranodal and solid organ sites
C85.9 Non-Hodgkin lymphoma, unspecified
C85.90 …… unspecified site
C85.91 …… lymph nodes of head, face, and neck
C85.92 …… intrathoracic lymph nodes
C85.93 …… intra-abdominal lymph nodes
C85.94 …… lymph nodes of axilla and upper limb
C85.95 …… lymph nodes of inguinal region and lower limb
C85.96 …… intrapelvic lymph nodes
C85.97 …… spleen
C85.98 …… lymph nodes of multiple sites
C85.99 …… extranodal and solid organ sites

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.