-
ICD-10-CM Codes
›
-
C00-D49
›
-
C81-C96
›
-
C88-
›
-
2023 ICD-10-CM Diagnosis Code C88.0
2023 ICD-10-CM Diagnosis Code C88.0
Waldenström macroglobulinemia
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
- C88.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- Short description: Waldenstrom macroglobulinemia
- The 2023 edition of ICD-10-CM C88.0 became effective on October 1, 2022.
- This is the American ICD-10-CM version of C88.0 - other international versions of ICD-10 C88.0 may differ.
Applicable To- Lymphoplasmacytic lymphoma with IgM-production
- Macroglobulinemia (idiopathic) (primary)
Type 1 ExcludesType 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as C88.0. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
The following code(s) above
C88.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
C88.0:
- C00-D49
2023 ICD-10-CM Range C00-D49
NeoplasmsNote- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
- C81-C96
2023 ICD-10-CM Range C81-C96
Malignant neoplasms of lymphoid, hematopoietic and related tissueType 2 Excludes- Kaposi's sarcoma of lymph nodes (C46.3)
- secondary and unspecified neoplasm of lymph nodes (C77.-)
- secondary neoplasm of bone marrow (C79.52)
- secondary neoplasm of spleen (C78.89)
- C88
ICD-10-CM Diagnosis Code C88
Malignant immunoproliferative diseases and certain other B-cell lymphomas
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
Type 1 Excludes- B-cell lymphoma, unspecified (C85.1-)
- personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)
- Macroglobulinemia
- Waldenstrˆm macroglobulinemia
- Waldenstroms macroglobulinemia
Clinical Information
- (mak-ro-glob-u-li-ne-me-uh) a condition in which the blood contains high levels of large proteins and is too thick to flow through small blood vessels. One type is waldenstrom's macroglobulinemia, which is a type of cancer.
- A clonal neoplasm of small b-lymphocytes, lymphoplasmacytoid cells, and plasma cells involving the bone marrow, lymph nodes, and the spleen. The majority of patients have a serum igm paraprotein. Lymphoplasmacytic lymphoma/waldenstrom's macroglobulinemia is a relatively rare condition accounting for approximately 2% of hematologic malignancies. Symptoms include: weakness and fatigue, hemorrhagic manifestations, weight loss, and visual disturbances. Physical findings include: hepatomegaly, splenomegaly, fundic changes, adenopathy, neurologic abnormalities, and purpura. The most common laboratory finding is anemia. Treatment includes: chemotherapy (alkylating agents, nucleoside analogues) radiotherapy, and plasmapheresis. Bone marrow transplant is being investigated. Asymptomatic patients may be monitored without treatment until complications occur.
- A lymphoproliferative disorder characterized by pleomorphic b-lymphocytes including plasma cells, with increased levels of monoclonal serum immunoglobulin m. There is lymphoplasmacytic cells infiltration into bone marrow and often other tissues, also known as lymphoplasmacytic lymphoma. Clinical features include anemia; hemorrhages; and hyperviscosity.
- A rare cancer of the lymph cells that causes the body to produce abnormal levels of plasma cells (plasmacytosis) and lymphocytes (lymphocytosis) in the bone marrow. Waldenstrom's macroglobulinemia may also cause a decrease in the number of red blood cells (anemia) and enlargement of the liver (hepatomegaly), spleen (splenomegaly), or glands (adenopathy).
- An indolent (slow-growing) type of non-hodgkin lymphoma marked by abnormal levels of igm antibodies in the blood and an enlarged liver, spleen, or lymph nodes.
- Lymphoplasmacytic lymphoma associated with bone marrow involvement and igm monoclonal gammopathy.
- Plasma cell dyscrasia resembling leukemia, with cells of lymphocytic, plasmacytic, or intermediate morphology, that secrete an igm monoclonal component.
ICD-10-CM C88.0 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
- 820 Lymphoma and leukemia with major o.r. Procedures with mcc
- 821 Lymphoma and leukemia with major o.r. Procedures with cc
- 822 Lymphoma and leukemia with major o.r. Procedures without cc/mcc
- 823 Lymphoma and non-acute leukemia with other procedures with mcc
- 824 Lymphoma and non-acute leukemia with other procedures with cc
- 825 Lymphoma and non-acute leukemia with other procedures without cc/mcc
- 840 Lymphoma and non-acute leukemia with mcc
- 841 Lymphoma and non-acute leukemia with cc
- 842 Lymphoma and non-acute leukemia without cc/mcc
Convert C88.0 to ICD-9-CM
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- 2022 (effective 10/1/2021): No change
- 2023 (effective 10/1/2022): No change
Code annotations containing back-references to C88.0:
- Disorder (of) - see also Disease
- glomerular (in) N05.9
ICD-10-CM Diagnosis Code N05.9
Unspecified nephritic syndrome with unspecified morphologic changes
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
- Waldenström macroglobulinemia C88.0
- Glomerulonephritis N05.9 - see also Nephritis
ICD-10-CM Diagnosis Code N05.9
Unspecified nephritic syndrome with unspecified morphologic changes
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
- in (due to)
- Waldenström macroglobulinemia C88.0
- Lymphoma (of) (malignant) C85.90
ICD-10-CM Diagnosis Code C85.90
Non-Hodgkin lymphoma, unspecified, unspecified site
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
- lymphoplasmacytic C83.0-
ICD-10-CM Diagnosis Code C83.0-
Small cell B-cell lymphoma
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
Applicable To- Lymphoplasmacytic lymphoma
- Nodal marginal zone lymphoma
- Non-leukemic variant of B-CLL
- Splenic marginal zone lymphoma
Type 1 Excludes- chronic lymphocytic leukemia (C91.1)
- mature T/NK-cell lymphomas (C84.-)
- Waldenström macroglobulinemia (C88.0)
- with IgM-production C88.0
- Macroglobulinemia (idiopathic) (primary) C88.0
- Waldenström
- syndrome or macroglobulinemia C88.0
ICD-10-CM Codes Adjacent To C88.0
C85.99 …… extranodal and solid organ sites
C86 Other specified types of T/NK-cell lymphoma
C86.0 Extranodal NK/T-cell lymphoma, nasal type
C86.1 Hepatosplenic T-cell lymphoma
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
C86.4 Blastic NK-cell lymphoma
C86.5 Angioimmunoblastic T-cell lymphoma
C86.6 Primary cutaneous CD30-positive T-cell proliferations
C88 Malignant immunoproliferative diseases and certain other B-cell lymphomas
C88.0
Waldenström macroglobulinemia
C88.2 Heavy chain disease
C88.3 Immunoproliferative small intestinal disease
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
C88.8 Other malignant immunoproliferative diseases
C88.9 Malignant immunoproliferative disease, unspecified
C90 Multiple myeloma and malignant plasma cell neoplasms
C90.00 …… not having achieved remission
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
