2020 ICD-10-CM Diagnosis Code C90.1

Plasma cell leukemia

    2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
  • C90.1 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2020 edition of ICD-10-CM C90.1 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of C90.1 - other international versions of ICD-10 C90.1 may differ.
Applicable To
  • Plasmacytic leukemia
The following code(s) above C90.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C90.1:
  • C00-D49
    2020 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C81-C96
    2020 ICD-10-CM Range C81-C96

    Malignant neoplasms of lymphoid, hematopoietic and related tissue

    Type 2 Excludes
    • Kaposi's sarcoma of lymph nodes (C46.3)
    • secondary and unspecified neoplasm of lymph nodes (C77.-)
    • secondary neoplasm of bone marrow (C79.52)
    • secondary neoplasm of spleen (C78.89)
    Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C90
    ICD-10-CM Diagnosis Code C90

    Multiple myeloma and malignant plasma cell neoplasms

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)
    Multiple myeloma and malignant plasma cell neoplasms
Clinical Information
  • A rare, aggressive variant of multiple myeloma characterized by the circulation of excessive plasma cells in the peripheral blood. It can be a primary manifestation of multiple myeloma or develop as a terminal complication during the disease.
  • An aggressive plasma cell neoplasm with usually short survival. It is characterized by the presence of neoplastic plasma cells in the peripheral blood. The peripheral blood plasma cells comprise more than 20% of the peripheral blood white cells. It may be the initial presentation of a plasma cell neoplasm or manifest as a terminal complication of plasma cell myeloma. Lymphadenopathy and organomegaly are frequent clinical signs, whereas bone pain and osteolytic lesions are less frequently present.
  • Rare type of acute leukemia in which the predominating cell in the peripheral blood is the plasma cell; it is often seen in conjunction with multiple myeloma and may be a variant form of that disease.
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
Code annotations containing back-references to C90.1:
  • Type 1 Excludes: C94
    ICD-10-CM Diagnosis Code C94

    Other leukemias of specified cell type

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • leukemic reticuloendotheliosis (C91.4-)
    • myelodysplastic syndromes (D46.-)
    • personal history of leukemia (Z85.6)
    • plasma cell leukemia (C90.1-)

Diagnosis Index entries containing back-references to C90.1:
  • Leukemia, leukemic C95.9-
    ICD-10-CM Diagnosis Code C95.9-

    Leukemia, unspecified

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    • plasma cell C90.1-
    • plasmacytic C90.1-

ICD-10-CM Codes Adjacent To C90.1
C88.2 Heavy chain disease
C88.3 Immunoproliferative small intestinal disease
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
C88.8 Other malignant immunoproliferative diseases
C88.9 Malignant immunoproliferative disease, unspecified
C90 Multiple myeloma and malignant plasma cell neoplasms
C90.0 Multiple myeloma
C90.00 …… not having achieved remission
C90.01 …… in remission
C90.02 …… in relapse
C90.1 Plasma cell leukemia
C90.10 …… not having achieved remission
C90.11 …… in remission
C90.12 …… in relapse
C90.2 Extramedullary plasmacytoma
C90.20 …… not having achieved remission
C90.21 …… in remission
C90.22 …… in relapse
C90.3 Solitary plasmacytoma
C90.30 …… not having achieved remission
C90.31 …… in remission

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.