2020 ICD-10-CM Diagnosis Code C91.10

Chronic lymphocytic leukemia of B-cell type not having achieved remission

    2016 2017 2018 2019 2020 Billable/Specific Code
  • C91.10 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Chronic lymphocytic leuk of B-cell type not achieve remis
  • The 2020 edition of ICD-10-CM C91.10 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of C91.10 - other international versions of ICD-10 C91.10 may differ.
Applicable To
  • Chronic lymphocytic leukemia of B-cell type with failed remission
  • Chronic lymphocytic leukemia of B-cell type NOS
The following code(s) above C91.10 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C91.10:
  • C00-D49
    2020 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C81-C96
    2020 ICD-10-CM Range C81-C96

    Malignant neoplasms of lymphoid, hematopoietic and related tissue

    Type 2 Excludes
    • Kaposi's sarcoma of lymph nodes (C46.3)
    • secondary and unspecified neoplasm of lymph nodes (C77.-)
    • secondary neoplasm of bone marrow (C79.52)
    • secondary neoplasm of spleen (C78.89)
    Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C91
    ICD-10-CM Diagnosis Code C91

    Lymphoid leukemia

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • personal history of leukemia (Z85.6)
    Lymphoid leukemia
  • C91.1
    ICD-10-CM Diagnosis Code C91.1

    Chronic lymphocytic leukemia of B-cell type

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Applicable To
    • Lymphoplasmacytic leukemia
    • Richter syndrome
    Type 1 Excludes
    • lymphoplasmacytic lymphoma (C83.0-)
    Chronic lymphocytic leukemia of B-cell type
Approximate Synonyms
  • Chronic lymphoid leukemia, disease
  • Leukemia, chronic lymphoid
Clinical Information
  • A chronic leukemia characterized by abnormal b-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (cll); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.
  • An indolent (slow-growing) cancer in which too many immature lymphocytes (white blood cells) are found mostly in the blood and bone marrow. Sometimes, in later stages of the disease, cancer cells are found in the lymph nodes and the disease is called small lymphocytic lymphoma.
  • Chronic leukemia characterized by morphologically mature but immunologically less mature lymphocytes; manifested by an abnormal accumulation of these cells in blood, bone marrow, and lymphatic tissue.
  • leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. In chronic lymphocytic leukemia (cll), there are too many lymphocytes, a type of white blood cell.cll is the second most common type of leukemia in adults. It often occurs during or after middle age, and is rare in children.usually cll does not cause any symptoms. If you have symptoms, they may include
    • painless swelling of the lymph nodes in the neck, underarm, stomach, or groin
    • fatigue
    • pain or a feeling of fullness below the ribs
    • fever and infection
    • weight loss
    tests that examine the blood, bone marrow, and lymph nodes diagnose cll. Your doctor may choose to just monitor you until symptoms appear or change. Treatments include radiation therapy, chemotherapy, surgery to remove the spleen, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells. nih: national cancer institute
  • The most common type of chronic lymphoid leukemia. It comprises 90% of chronic lymphoid leukemias in the United States. Morphologically, the neoplastic cells are small, round b-lymphocytes. This type of leukemia is not considered to be curable with available therapy. (who, 2001)
ICD-10-CM C91.10 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 820 Lymphoma and leukemia with major o.r. Procedure with mcc
  • 821 Lymphoma and leukemia with major o.r. Procedure with cc
  • 822 Lymphoma and leukemia with major o.r. Procedure without cc/mcc
  • 823 Lymphoma and non-acute leukemia with other procedure with mcc
  • 824 Lymphoma and non-acute leukemia with other procedure with cc
  • 825 Lymphoma and non-acute leukemia with other procedure without cc/mcc
  • 840 Lymphoma and non-acute leukemia with mcc
  • 841 Lymphoma and non-acute leukemia with cc
  • 842 Lymphoma and non-acute leukemia without cc/mcc

Convert C91.10 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
ICD-10-CM Codes Adjacent To C91.10
C90.3 Solitary plasmacytoma
C90.30 …… not having achieved remission
C90.31 …… in remission
C90.32 …… in relapse
C91 Lymphoid leukemia
C91.0 Acute lymphoblastic leukemia [ALL]
C91.00 Acute lymphoblastic leukemia not having achieved remission
C91.01 Acute lymphoblastic leukemia, in remission
C91.02 Acute lymphoblastic leukemia, in relapse
C91.1 Chronic lymphocytic leukemia of B-cell type
C91.10 …… not having achieved remission
C91.11 …… in remission
C91.12 …… in relapse
C91.3 Prolymphocytic leukemia of B-cell type
C91.30 …… not having achieved remission
C91.31 …… in remission
C91.32 …… in relapse
C91.4 Hairy cell leukemia
C91.40 …… not having achieved remission
C91.41 …… in remission
C91.42 …… in relapse

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.