2019 ICD-10-CM Diagnosis Code C91.3

Prolymphocytic leukemia of B-cell type

    2016 2017 2018 2019 Non-Billable/Non-Specific Code
  • C91.3 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2019 edition of ICD-10-CM C91.3 became effective on October 1, 2018.
  • This is the American ICD-10-CM version of C91.3 - other international versions of ICD-10 C91.3 may differ.
The following code(s) above C91.3 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C91.3:
  • C00-D49
    2019 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C81-C96
    2019 ICD-10-CM Range C81-C96

    Malignant neoplasms of lymphoid, hematopoietic and related tissue

    Type 2 Excludes
    • Kaposi's sarcoma of lymph nodes (C46.3)
    • secondary and unspecified neoplasm of lymph nodes (C77.-)
    • secondary neoplasm of bone marrow (C79.52)
    • secondary neoplasm of spleen (C78.89)
    Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C91
    ICD-10-CM Diagnosis Code C91

    Lymphoid leukemia

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • personal history of leukemia (Z85.6)
    Lymphoid leukemia
Clinical Information
  • A chronic leukemia characterized by a large number of circulating prolymphocytes. It can arise spontaneously or as a consequence of transformation of chronic lymphocytic leukemia.
  • A malignant b-cell lymphoproliferative process affecting the blood, bone marrow, and spleen. The b-prolymphocytes are medium-sized, round lymphoid cells with prominent nucleoli. The b-prolymphocytes must exceed 55% of lymphoid cells in the blood. Cases of transformed chronic lymphocytic leukemia (cll) and cll with increased prolymphocytes are excluded. The prognosis is poor. (who, 2001)
  • A mature b- or t- cell leukemia with progressive clinical course. It is characterized by the presence of medium-sized lymphocytes with visible nucleoli (prolymphocytes) in the peripheral blood, bone marrow, and spleen.
  • A neoplasm of prolymphocytes affecting the blood, bone marrow, and spleen. It is characterized by prolymphocytes exceeding 55% of the lymphoid cells in the blood and profound splenomegaly.
  • A type of chronic lymphocytic leukemia (cll) in which too many immature white blood cells (prolymphocytes) are found in the blood and bone marrow. Pll usually progresses more rapidly than classic cll.
  • Pll. A type of chronic lymphocyctic leukemia (cll), in which too many immature white blood cells (prolymphocytes) are found in the blood and bone marrow. Pll usually progresses more rapidly than classic cll.
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change

Diagnosis Index entries containing back-references to C91.3:

ICD-10-CM Codes Adjacent To C91.3
C90.32 …… in relapse
C91 Lymphoid leukemia
C91.0 Acute lymphoblastic leukemia [ALL]
C91.00 Acute lymphoblastic leukemia not having achieved remission
C91.01 Acute lymphoblastic leukemia, in remission
C91.02 Acute lymphoblastic leukemia, in relapse
C91.1 Chronic lymphocytic leukemia of B-cell type
C91.10 …… not having achieved remission
C91.11 …… in remission
C91.12 …… in relapse
C91.3 Prolymphocytic leukemia of B-cell type
C91.30 …… not having achieved remission
C91.31 …… in remission
C91.32 …… in relapse
C91.4 Hairy cell leukemia
C91.40 …… not having achieved remission
C91.41 …… in remission
C91.42 …… in relapse
C91.5 Adult T-cell lymphoma/leukemia (HTLV-1-associated)
C91.50 …… not having achieved remission
C91.51 …… in remission

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.