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ICD-10-CM Codes
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C00-D49
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C81-C96
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C91-
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2023 ICD-10-CM Diagnosis Code C91.40
2023 ICD-10-CM Diagnosis Code C91.40
Hairy cell leukemia not having achieved remission
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
- C91.40 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- The 2023 edition of ICD-10-CM C91.40 became effective on October 1, 2022.
- This is the American ICD-10-CM version of C91.40 - other international versions of ICD-10 C91.40 may differ.
Applicable To- Hairy cell leukemia with failed remission
- Hairy cell leukemia NOS
The following code(s) above
C91.40 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
C91.40:
- C00-D49
2023 ICD-10-CM Range C00-D49
NeoplasmsNote- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
Neoplasms - C81-C96
2023 ICD-10-CM Range C81-C96
Malignant neoplasms of lymphoid, hematopoietic and related tissueType 2 Excludes- Kaposi's sarcoma of lymph nodes (C46.3)
- secondary and unspecified neoplasm of lymph nodes (C77.-)
- secondary neoplasm of bone marrow (C79.52)
- secondary neoplasm of spleen (C78.89)
Malignant neoplasms of lymphoid, hematopoietic and related tissue - C91
ICD-10-CM Diagnosis Code C91
Lymphoid leukemia
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
Type 1 Excludes- personal history of leukemia (Z85.6)
Lymphoid leukemia - C91.4
ICD-10-CM Diagnosis Code C91.4
Hairy cell leukemia
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
Applicable To- Leukemic reticuloendotheliosis
Hairy cell leukemia
Approximate Synonyms
- Hairy cell leukemia (clinical)
- Hairy cell leukemia, arm ln
- Hairy cell leukemia, axillary ln
- Hairy cell leukemia, head ln
- Hairy cell leukemia, inguinal ln
- Hairy cell leukemia, leg ln
- Hairy cell leukemia, neck ln
- Leukemia, hairy cell
- Leukemic reticuloendotheliosis
- Leukemic reticuloendotheliosis extranod or solitar
- Leukemic reticuloendotheliosis intrapelvic lymph n
- Leukemic reticuloendotheliosis of extranodal and/or solid organ site
- Leukemic reticuloendotheliosis of intra-abdominal lymph nodes
- Leukemic reticuloendotheliosis of intrapelvic lymph nodes
- Leukemic reticuloendotheliosis of intrathoracic lymph nodes
- Leukemic reticuloendotheliosis of lymph nodes of axilla
- Leukemic reticuloendotheliosis of lymph nodes of head
- Leukemic reticuloendotheliosis of lymph nodes of inguinal region
- Leukemic reticuloendotheliosis of lymph nodes of lower limb
- Leukemic reticuloendotheliosis of lymph nodes of multiple sites
- Leukemic reticuloendotheliosis of lymph nodes of neck
- Leukemic reticuloendotheliosis of lymph nodes of upper limb
- Leukemic reticuloendotheliosis of spleen
- Leukemic reticuloendotheliosis spleen
Clinical Information
- A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow.
- A rare neoplasm of small b-lymphocytes with "hairy" projections in bone marrow, spleen, and peripheral blood. Most patients are middle-aged to elderly adults and present with splenomegaly and pancytopenia. (who, 2001)
- A rare type of leukemia in which abnormal b-lymphocytes (a type of white blood cell) are present in the bone marrow, spleen, and peripheral blood. When viewed under a microscope, these cells appear to be covered with tiny hair-like projections.
- Neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of hairy or flagellated cells in the blood and bone marrow.
ICD-10-CM C91.40 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
- 011 Tracheostomy for face, mouth and neck diagnoses or laryngectomy with mcc
- 012 Tracheostomy for face, mouth and neck diagnoses or laryngectomy with cc
- 013 Tracheostomy for face, mouth and neck diagnoses or laryngectomy without cc/mcc
- 820 Lymphoma and leukemia with major o.r. Procedures with mcc
- 821 Lymphoma and leukemia with major o.r. Procedures with cc
- 822 Lymphoma and leukemia with major o.r. Procedures without cc/mcc
- 823 Lymphoma and non-acute leukemia with other procedures with mcc
- 824 Lymphoma and non-acute leukemia with other procedures with cc
- 825 Lymphoma and non-acute leukemia with other procedures without cc/mcc
- 840 Lymphoma and non-acute leukemia with mcc
- 841 Lymphoma and non-acute leukemia with cc
- 842 Lymphoma and non-acute leukemia without cc/mcc
Convert C91.40 to ICD-9-CM
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- 2022 (effective 10/1/2021): No change
- 2023 (effective 10/1/2022): No change
ICD-10-CM Codes Adjacent To C91.40
C91.02 Acute lymphoblastic leukemia, in relapse
C91.1 Chronic lymphocytic leukemia of B-cell type
C91.10 …… not having achieved remission
C91.3 Prolymphocytic leukemia of B-cell type
C91.30 …… not having achieved remission
C91.4 Hairy cell leukemia
C91.40
…… not having achieved remission
C91.5 Adult T-cell lymphoma/leukemia (HTLV-1-associated)
C91.50 …… not having achieved remission
C91.6 Prolymphocytic leukemia of T-cell type
C91.60 …… not having achieved remission
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.