2021 ICD-10-CM Diagnosis Code C92.2

Atypical chronic myeloid leukemia, BCR/ABL-negative

    2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
  • C92.2 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2021 edition of ICD-10-CM C92.2 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of C92.2 - other international versions of ICD-10 C92.2 may differ.
The following code(s) above C92.2 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C92.2:
  • C00-D49
    2021 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C81-C96
    2021 ICD-10-CM Range C81-C96

    Malignant neoplasms of lymphoid, hematopoietic and related tissue

    Type 2 Excludes
    • Kaposi's sarcoma of lymph nodes (C46.3)
    • secondary and unspecified neoplasm of lymph nodes (C77.-)
    • secondary neoplasm of bone marrow (C79.52)
    • secondary neoplasm of spleen (C78.89)
    Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C92
    ICD-10-CM Diagnosis Code C92

    Myeloid leukemia

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Includes
    • granulocytic leukemia
    • myelogenous leukemia
    Type 1 Excludes
    • personal history of leukemia (Z85.6)
    Myeloid leukemia
Clinical Information
  • A myelodysplastic/myeloproliferative disease characterized by the principal involvement of the neutrophil series with leukocytosis and multilineage dysplasia. The neoplastic cells do not have a philadelphia chromosome or the bcr/abl fusion gene. The prognosis is usually poor. (who, 2001)
  • A myelodysplastic/myeloproliferative disorder characterized by myelodysplasia associated with bone marrow and peripheral blood patterns similar to chronic myeloid leukemia, but cytogenetically lacking a philadelphia chromosome or bcr/abl fusion gene (genes, abl).
  • A myelodysplastic/myeloproliferative neoplasm characterized by the principal involvement of the neutrophil series with leukocytosis and multilineage dysplasia. The neoplastic cells do not have a philadelphia chromosome or the bcr/abl fusion gene. The prognosis is usually poor. (who, 2001)
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to C92.2:
  • Type 1 Excludes: C92.1
    , D47.1
    ICD-10-CM Diagnosis Code C92.1

    Chronic myeloid leukemia, BCR/ABL-positive

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Applicable To
    • Chronic myelogenous leukemia, Philadelphia chromosome (Ph1) positive
    • Chronic myelogenous leukemia, t(9;22) (q34;q11)
    • Chronic myelogenous leukemia with crisis of blast cells
    Type 1 Excludes
    • atypical chronic myeloid leukemia BCR/ABL-negative (C92.2-)
    • chronic myelomonocytic leukemia (C93.1-)
    • chronic myeloproliferative disease (D47.1)
    ICD-10-CM Diagnosis Code D47.1

    Chronic myeloproliferative disease

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Chronic neutrophilic leukemia
    • Myeloproliferative disease, unspecified
    Type 1 Excludes
    • atypical chronic myeloid leukemia BCR/ABL-negative (C92.2-)
    • chronic myeloid leukemia BCR/ABL-positive (C92.1-)
    • myelofibrosis NOS (D75.81)
    • myelophthisic anemia (D61.82)
    • myelophthisis (D61.82)
    • secondary myelofibrosis NOS (D75.81)

Diagnosis Index entries containing back-references to C92.2:
  • Leukemia, leukemic C95.9-
    ICD-10-CM Diagnosis Code C95.9-

    Leukemia, unspecified

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    • chronic myeloid, BCR/ABL-positive C92.1-
      ICD-10-CM Diagnosis Code C92.1-

      Chronic myeloid leukemia, BCR/ABL-positive

        2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
      Applicable To
      • Chronic myelogenous leukemia, Philadelphia chromosome (Ph1) positive
      • Chronic myelogenous leukemia, t(9;22) (q34;q11)
      • Chronic myelogenous leukemia with crisis of blast cells
      Type 1 Excludes
      • atypical chronic myeloid leukemia BCR/ABL-negative (C92.2-)
      • chronic myelomonocytic leukemia (C93.1-)
      • chronic myeloproliferative disease (D47.1)
      • atypical, BCR/ABL-negative C92.2-
    • atypical chronic myeloid, BCR/ABL-negative C92.2-

ICD-10-CM Codes Adjacent To C92.2
C91.92 …… in relapse
C92 Myeloid leukemia
C92.0 Acute myeloblastic leukemia
C92.00 …… not having achieved remission
C92.01 …… in remission
C92.02 …… in relapse
C92.1 Chronic myeloid leukemia, BCR/ABL-positive
C92.10 …… not having achieved remission
C92.11 …… in remission
C92.12 …… in relapse
C92.2 Atypical chronic myeloid leukemia, BCR/ABL-negative
C92.20 …… not having achieved remission
C92.21 …… in remission
C92.22 …… in relapse
C92.3 Myeloid sarcoma
C92.30 …… not having achieved remission
C92.31 …… in remission
C92.32 …… in relapse
C92.4 Acute promyelocytic leukemia
C92.40 …… not having achieved remission
C92.41 …… in remission

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.