2020 ICD-10-CM Diagnosis Code C92.50

Acute myelomonocytic leukemia, not having achieved remission

    2016 2017 2018 2019 2020 Billable/Specific Code
  • C92.50 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM C92.50 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of C92.50 - other international versions of ICD-10 C92.50 may differ.
Applicable To
  • Acute myelomonocytic leukemia with failed remission
  • Acute myelomonocytic leukemia NOS
The following code(s) above C92.50 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C92.50:
  • C00-D49
    2020 ICD-10-CM Range C00-D49


    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
  • C81-C96
    2020 ICD-10-CM Range C81-C96

    Malignant neoplasms of lymphoid, hematopoietic and related tissue

    Type 2 Excludes
    • Kaposi's sarcoma of lymph nodes (C46.3)
    • secondary and unspecified neoplasm of lymph nodes (C77.-)
    • secondary neoplasm of bone marrow (C79.52)
    • secondary neoplasm of spleen (C78.89)
    Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C92
    ICD-10-CM Diagnosis Code C92

    Myeloid leukemia

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    • granulocytic leukemia
    • myelogenous leukemia
    Type 1 Excludes
    • personal history of leukemia (Z85.6)
    Myeloid leukemia
  • C92.5
    ICD-10-CM Diagnosis Code C92.5

    Acute myelomonocytic leukemia

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Applicable To
    • AML M4
    • AML M4 Eo with inv(16) or t(16;16)
    Acute myelomonocytic leukemia
Approximate Synonyms
  • Acute myeloid leukemia, disease
  • Acute myelomonocytic leukemia - eosinophilic variant
  • Acute myelomonocytic leukemia with eosinophilia
  • Acute myelomonocytic leukemia, fab m4
  • Leukemia, acute myeloid
  • Leukemia, acute myelomonocytic, fab m4
Clinical Information
  • A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of monocytic origin.
  • An acute leukemia characterized by the proliferation of both neutrophil and monocyte precursors. Patients typically present with anemia, thrombocytopenia, fever and fatigue. This type of leukemia frequently responds to aggressive therapy. (who, 2001)
ICD-10-CM C92.50 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 820 Lymphoma and leukemia with major o.r. Procedure with mcc
  • 821 Lymphoma and leukemia with major o.r. Procedure with cc
  • 822 Lymphoma and leukemia with major o.r. Procedure without cc/mcc
  • 834 Acute leukemia without major o.r. Procedure with mcc
  • 835 Acute leukemia without major o.r. Procedure with cc
  • 836 Acute leukemia without major o.r. Procedure without cc/mcc
  • 837 Chemotherapy with acute leukemia as sdx or with high dose chemotherapy agent with mcc
  • 838 Chemotherapy with acute leukemia as sdx with cc or high dose chemotherapy agent
  • 839 Chemotherapy with acute leukemia as sdx without cc/mcc

Convert C92.50 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
ICD-10-CM Codes Adjacent To C92.50
C92.22 …… in relapse
C92.3 Myeloid sarcoma
C92.30 …… not having achieved remission
C92.31 …… in remission
C92.32 …… in relapse
C92.4 Acute promyelocytic leukemia
C92.40 …… not having achieved remission
C92.41 …… in remission
C92.42 …… in relapse
C92.5 Acute myelomonocytic leukemia
C92.50 …… not having achieved remission
C92.51 …… in remission
C92.52 …… in relapse
C92.6 Acute myeloid leukemia with 11q23-abnormality
C92.60 …… not having achieved remission
C92.61 …… in remission
C92.62 …… in relapse
C92.A Acute myeloid leukemia with multilineage dysplasia
C92.A0 …… not having achieved remission
C92.A1 …… in remission
C92.A2 …… in relapse

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.