2021 ICD-10-CM Diagnosis Code C93.1

Chronic myelomonocytic leukemia

    2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
  • C93.1 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2021 edition of ICD-10-CM C93.1 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of C93.1 - other international versions of ICD-10 C93.1 may differ.
Applicable To
  • Chronic monocytic leukemia
  • CMML-1
  • CMML-2
  • CMML with eosinophilia
Code Also
Code Also Help
A code also note instructs that 2 codes may be required to fully describe a condition but the sequencing of the two codes is discretionary, depending on the severity of the conditions and the reason for the encounter.
  • , if applicable, eosinophilia (
    ICD-10-CM Diagnosis Code D72.18

    Eosinophilia in diseases classified elsewhere

      2021 - New Code Billable/Specific Code
    Code First
    • underlying disease, such as:
    • chronic myelomonocytic leukemia (C93.1-)
    D72.18
    )
The following code(s) above C93.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C93.1:
  • C00-D49
    2021 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C81-C96
    2021 ICD-10-CM Range C81-C96

    Malignant neoplasms of lymphoid, hematopoietic and related tissue

    Type 2 Excludes
    • Kaposi's sarcoma of lymph nodes (C46.3)
    • secondary and unspecified neoplasm of lymph nodes (C77.-)
    • secondary neoplasm of bone marrow (C79.52)
    • secondary neoplasm of spleen (C78.89)
    Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C93
    ICD-10-CM Diagnosis Code C93

    Monocytic leukemia

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Includes
    • monocytoid leukemia
    Type 1 Excludes
    • personal history of leukemia (Z85.6)
    Monocytic leukemia
Clinical Information
  • A chronic myelomonocytic leukemia characterized by a peripheral blood eosinophil count of equal or greater than 1.5x10e9/l, and absence of pdgfra or pdgfrb gene abnormalities.
  • A chronic myelomonocytic leukemia characterized by the presence of 10-19 percent blasts in the bone marrow and 5-19 percent blasts in the peripheral blood or by the presence of auer rods regardless of the blasts count.
  • A chronic myelomonocytic leukemia characterized by the presence of less than 10 percent blasts in the bone marrow and less than 5 percent blasts in the peripheral blood.
  • A myelodysplastic/myeloproliferative neoplasm which is characterized by persistent monocytosis, absence of a philadelphia chromosome and bcr/abl fusion gene, fewer than 20 percent blasts in the bone marrow and blood, myelodysplasia, and absence of pdgfra or pdgfrb rearrangement.
  • A myelodysplastic-myeloproliferative disease characterized by monocytosis, increased monocytes in the bone marrow, variable degrees of dysplasia, but an absence of immature granulocytes in the blood.
  • A slowly progressing type of myelodysplastic/myeloproliferative disease in which too many myelomonocytes (a type of white blood cell) are in the bone marrow, crowding out other normal blood cells, such as other white blood cells, red blood cells, and platelets.
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to C93.1:
  • Code Also: D47.02
    ICD-10-CM Diagnosis Code D47.02

    Systemic mastocytosis

      2018 - New Code 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Indolent systemic mastocytosis
    • Isolated bone marrow mastocytosis
    • Smoldering systemic mastocytosis
    • Systemic mastocytosis, with an associated hematological non-mast cell lineage disease (SM-AHNMD)
    Code Also
    • , if applicable, any associated hematological non-mast cell lineage disease, such as:
    • acute myeloid leukemia (C92.6-, C92.A-)
    • chronic myelomonocytic leukemia (C93.1-)
    • essential thrombocytosis (D47.3)
    • hypereosinophilic syndrome (D72.1)
    • myelodysplastic syndrome (D46.9)
    • myeloproliferative syndrome (D47.1)
    • non-Hodgkin lymphoma (C82-C85)
    • plasma cell myeloma (C90.0-)
    • polycythemia vera (D45)
    Type 1 Excludes
    • aggressive systemic mastocytosis (C96.21)
    • mast cell leukemia (C94.3-)
  • Code First: D72.18
    ICD-10-CM Diagnosis Code D72.18

    Eosinophilia in diseases classified elsewhere

      2021 - New Code Billable/Specific Code
    Code First
    • underlying disease, such as:
    • chronic myelomonocytic leukemia (C93.1-)
  • Type 1 Excludes: C92.1
    , D46.Z
    ICD-10-CM Diagnosis Code C92.1

    Chronic myeloid leukemia, BCR/ABL-positive

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Applicable To
    • Chronic myelogenous leukemia, Philadelphia chromosome (Ph1) positive
    • Chronic myelogenous leukemia, t(9;22) (q34;q11)
    • Chronic myelogenous leukemia with crisis of blast cells
    Type 1 Excludes
    • atypical chronic myeloid leukemia BCR/ABL-negative (C92.2-)
    • chronic myelomonocytic leukemia (C93.1-)
    • chronic myeloproliferative disease (D47.1)
    ICD-10-CM Diagnosis Code D46.Z

    Other myelodysplastic syndromes

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Type 1 Excludes
    • chronic myelomonocytic leukemia (C93.1-)

Diagnosis Index entries containing back-references to C93.1:
  • Leukemia, leukemic C95.9-
    ICD-10-CM Diagnosis Code C95.9-

    Leukemia, unspecified

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    • chronic monocytic C93.1-
    • chronic myelomonocytic C93.1-
    • CMML C93.1- (-1) (-2) (with eosinophilia)
  • Naegeli's
    • leukemia, monocytic C93.1-

ICD-10-CM Codes Adjacent To C93.1
C92.Z2 …… in relapse
C92.9 Myeloid leukemia, unspecified
C92.90 …… not having achieved remission
C92.91 …… in remission
C92.92 …… in relapse
C93 Monocytic leukemia
C93.0 Acute monoblastic/monocytic leukemia
C93.00 …… not having achieved remission
C93.01 …… in remission
C93.02 …… in relapse
C93.1 Chronic myelomonocytic leukemia
C93.10 …… not having achieved remission
C93.11 …… in remission
C93.12 …… in relapse
C93.3 Juvenile myelomonocytic leukemia
C93.30 …… not having achieved remission
C93.31 …… in remission
C93.32 …… in relapse
C93.Z Other monocytic leukemia
C93.Z0 …… not having achieved remission
C93.Z1 …… in remission

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.