1. ICD-10-CM Codes
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2. C00-D49 Neoplasms
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3. C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue
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4. C95- Leukemia of unspecified cell type
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5. 2021 ICD-10-CM Diagnosis Code C95

2021 ICD-10-CM Diagnosis Code C95

Leukemia of unspecified cell type

2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code

• C95 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
• The 2021 edition of ICD-10-CM C95 became effective on October 1, 2020.
• This is the American ICD-10-CM version of C95 - other international versions of ICD-10 C95 may differ.

• (loo-kee-mee-a) cancer of blood-forming tissue.
• A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.
• A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (from the merck manual, 2006)
• A progressive, proliferative disease of blood cells, originating from myeloid or lymphoid stem cells.
• Cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream.
• Leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, however, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work.there are different types of leukemia, including
  • acute lymphocytic leukemia
  • acute myeloid leukemia
  • chronic lymphocytic leukemia
  • chronic myeloid leukemia
  leukemia can develop quickly or slowly. Chronic leukemia grows slowly. In acute leukemia, the cells are very abnormal and their number increases rapidly. Adults can get either type; childen with leukemia most often have an acute type.some leukemias can often be cured. Other types are hard to cure, but you can often control them. Treatments may include chemotherapy, radiation and stem cell transplantation. Even if symptoms disappear, you might need therapy to prevent a relapse. nih: national cancer institute
• Progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow; classified according to degree of cell differentiation as acute or chronic, and according to predominant type of cell involved as myelogenous or lymphocytic.

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change

• Type 1 Excludes: D72.825
  ICD-10-CM Diagnosis Code D72.825

  Bandemia

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Applicable To

  • Bandemia without diagnosis of specific infection

  Type 1 Excludes

  • confirmed infection - code to infection
  • leukemia (C91.-, C92.-, C93.-, C94.-, C95.-)

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.