2021 ICD-10-CM Diagnosis Code C96.A

Histiocytic sarcoma

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • C96.A is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM C96.A became effective on October 1, 2020.
  • This is the American ICD-10-CM version of C96.A - other international versions of ICD-10 C96.A may differ.
Applicable To
  • Malignant histiocytosis
The following code(s) above C96.A contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C96.A:
  • C00-D49
    2021 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • C81-C96
    2021 ICD-10-CM Range C81-C96

    Malignant neoplasms of lymphoid, hematopoietic and related tissue

    Type 2 Excludes
    • Kaposi's sarcoma of lymph nodes (C46.3)
    • secondary and unspecified neoplasm of lymph nodes (C77.-)
    • secondary neoplasm of bone marrow (C79.52)
    • secondary neoplasm of spleen (C78.89)
    Malignant neoplasms of lymphoid, hematopoietic and related tissue
  • C96
    ICD-10-CM Diagnosis Code C96

    Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)
    Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue
Approximate Synonyms
  • Lymphoma malignant histiocytosis
  • Lymphoma spleen, malignant histiocytosis
  • Malignant histiocytosis
  • Malignant histiocytosis (clinical)
  • Malignant histiocytosis of intra-abdominal lymph nodes
  • Malignant histiocytosis of intrapelvic lymph nodes
  • Malignant histiocytosis of intrathoracic lymph nodes
  • Malignant histiocytosis of lymph nodes of axilla
  • Malignant histiocytosis of lymph nodes of head
  • Malignant histiocytosis of lymph nodes of inguinal region
  • Malignant histiocytosis of lymph nodes of lower limb
  • Malignant histiocytosis of lymph nodes of multiple sites
  • Malignant histiocytosis of lymph nodes of neck
  • Malignant histiocytosis of lymph nodes of upper limb
  • Malignant histiocytosis of spleen
  • Malignant histiocytosis, arm ln
  • Malignant histiocytosis, axillary ln
  • Malignant histiocytosis, head ln
  • Malignant histiocytosis, inguinal ln
  • Malignant histiocytosis, leg ln
  • Malignant histiocytosis, neck ln
Clinical Information
  • A malignant neoplasm composed of cells resembling histiocytes.
  • A malignant neoplasm of large lymphocytes, which resemble histiocytes.
  • A rare, usually progressive disorder comprising an invasive proliferation of neoplastic histiocytes. Many previous cases are now thought to represent anaplastic large-cell lymphoma.
  • An aggressive malignant neoplasm with a poor response to therapy, usually presenting as stage iii/iv disease. It is characterized by the presence of neoplastic cells with morphologic and immunophenotypic characteristics similar to those seen in mature histiocytes.
  • An antiquated term referring to cases of systemic non-hodgkin lymphomas which are composed of large, atypical neoplastic lymphoid cells and cases of hemophagocytic syndromes. In the past, cases of anaplastic large cells lymphoma were called malignant histiocytosis.
  • An antiquated term referring to large cell lymphomas.
  • An outdated term referring to non-hodgkin lymphomas made up of large abnormal lymphoid cells. Histiocytic lymphomas include mature b-cell and t-cell non-hodgkin lymphomas. Many tumors that were once called histiocytic lymphomas are now considered to be a type of large cell lymphoma.
  • Malignant neoplasms composed of macrophages or dendritic cells. Most histiocytic sarcomas present as localized tumor masses without a leukemic phase. Though the biological behavior of these neoplasms resemble lymphomas, their cell lineage is histiocytic not lymphoid.
ICD-10-CM C96.A is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 011 Tracheostomy for face, mouth and neck diagnoses or laryngectomy with mcc
  • 012 Tracheostomy for face, mouth and neck diagnoses or laryngectomy with cc
  • 013 Tracheostomy for face, mouth and neck diagnoses or laryngectomy without cc/mcc
  • 820 Lymphoma and leukemia with major o.r. Procedures with mcc
  • 821 Lymphoma and leukemia with major o.r. Procedures with cc
  • 822 Lymphoma and leukemia with major o.r. Procedures without cc/mcc
  • 823 Lymphoma and non-acute leukemia with other procedures with mcc
  • 824 Lymphoma and non-acute leukemia with other procedures with cc
  • 825 Lymphoma and non-acute leukemia with other procedures without cc/mcc
  • 840 Lymphoma and non-acute leukemia with mcc
  • 841 Lymphoma and non-acute leukemia with cc
  • 842 Lymphoma and non-acute leukemia without cc/mcc

Convert C96.A to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to C96.A:
  • Code First: M36.1
    ICD-10-CM Diagnosis Code M36.1

    Arthropathy in neoplastic disease

      2016 2017 2018 2019 2020 2021 Billable/Specific Code Manifestation Code
    Code First
    • underlying neoplasm, such as:
    • leukemia (C91-C95)
    • malignant histiocytosis (C96.A)
    • multiple myeloma (C90.0)
  • Type 1 Excludes: D76
    , D76
    ICD-10-CM Diagnosis Code D76

    Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • (Abt-) Letterer-Siwe disease (C96.0)
    • eosinophilic granuloma (C96.6)
    • Hand-Schüller-Christian disease (C96.5)
    • histiocytic medullary reticulosis (C96.9)
    • histiocytic sarcoma (C96.A)
    • histiocytosis X, multifocal (C96.5)
    • histiocytosis X, unifocal (C96.6)
    • Langerhans-cell histiocytosis, multifocal (C96.5)
    • Langerhans-cell histiocytosis NOS (C96.6)
    • Langerhans-cell histiocytosis, unifocal (C96.6)
    • leukemic reticuloendotheliosis (C91.4-)
    • lipomelanotic reticulosis (I89.8)
    • malignant histiocytosis (C96.A)
    • malignant reticulosis (C86.0)
    • nonlipid reticuloendotheliosis (C96.0)
    ICD-10-CM Diagnosis Code D76

    Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • (Abt-) Letterer-Siwe disease (C96.0)
    • eosinophilic granuloma (C96.6)
    • Hand-Schüller-Christian disease (C96.5)
    • histiocytic medullary reticulosis (C96.9)
    • histiocytic sarcoma (C96.A)
    • histiocytosis X, multifocal (C96.5)
    • histiocytosis X, unifocal (C96.6)
    • Langerhans-cell histiocytosis, multifocal (C96.5)
    • Langerhans-cell histiocytosis NOS (C96.6)
    • Langerhans-cell histiocytosis, unifocal (C96.6)
    • leukemic reticuloendotheliosis (C91.4-)
    • lipomelanotic reticulosis (I89.8)
    • malignant histiocytosis (C96.A)
    • malignant reticulosis (C86.0)
    • nonlipid reticuloendotheliosis (C96.0)

Diagnosis Index entries containing back-references to C96.A:
  • Arthropathy M12.9
    - see also Arthritis
    ICD-10-CM Diagnosis Code M12.9

    Arthropathy, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    • in (due to)
      • malignant histiocytosis C96.A
  • Histiocytosis D76.3
    ICD-10-CM Diagnosis Code D76.3

    Other histiocytosis syndromes

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Reticulohistiocytoma (giant-cell)
    • Sinus histiocytosis with massive lymphadenopathy
    • Xanthogranuloma
    • malignant C96.A
  • Lymphoma (of) (malignant) C85.90
    ICD-10-CM Diagnosis Code C85.90

    Non-Hodgkin lymphoma, unspecified, unspecified site

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    • histiocytic C85.9-
      ICD-10-CM Diagnosis Code C85.9-

      Non-Hodgkin lymphoma, unspecified

        2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
      Applicable To
      • Lymphoma NOS
      • Malignant lymphoma NOS
      • Non-Hodgkin lymphoma NOS
      • true C96.A
    • true histiocytic C96.A
  • Reticulosis (skin)
    • histiocytic medullary C96.A
  • Sarcoma (of) - see also Neoplasm, connective tissue, malignant
    • histiocytic C96.A

ICD-10-CM Codes Adjacent To C96.A
C96 Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue
C96.0 Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis
C96.2 Malignant mast cell neoplasm
C96.20 …… unspecified
C96.21 Aggressive systemic mastocytosis
C96.22 Mast cell sarcoma
C96.29 Other malignant mast cell neoplasm
C96.4 Sarcoma of dendritic cells (accessory cells)
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
C96.6 Unifocal Langerhans-cell histiocytosis
C96.A Histiocytic sarcoma
C96.Z Other specified malignant neoplasms of lymphoid, hematopoietic and related tissue
C96.9 Malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecified
D00 Carcinoma in situ of oral cavity, esophagus and stomach
D00.0 Carcinoma in situ of lip, oral cavity and pharynx
D00.00 Carcinoma in situ of oral cavity, unspecified site
D00.01 Carcinoma in situ of labial mucosa and vermilion border
D00.02 Carcinoma in situ of buccal mucosa
D00.03 Carcinoma in situ of gingiva and edentulous alveolar ridge
D00.04 Carcinoma in situ of soft palate
D00.05 Carcinoma in situ of hard palate

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.