2023 ICD-10-CM Diagnosis Code D46.B

Refractory cytopenia with multilineage dysplasia and ring sideroblasts

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • D46.B is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Refract cytopenia w multilin dysplasia and ring sideroblasts
  • The 2023 edition of ICD-10-CM D46.B became effective on October 1, 2022.
  • This is the American ICD-10-CM version of D46.B - other international versions of ICD-10 D46.B may differ.
Applicable To
  • RCMD RS
The following code(s) above D46.B contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D46.B:
  • C00-D49
    2023 ICD-10-CM Range C00-D49

    Neoplasms

    Note
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms
  • D37-D48
    2023 ICD-10-CM Range D37-D48

    Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes

    Note
    • Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made.
    Type 1 Excludes
    • neoplasms of unspecified behavior (D49.-)
    Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
  • D46
    ICD-10-CM Diagnosis Code D46

    Myelodysplastic syndromes

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • drug-induced aplastic anemia (D61.1)
    Use Additional
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
    Myelodysplastic syndromes
Approximate Synonyms
  • Refractory cytopenia with multilineage dysplasia and ringed sideroblasts
Clinical Information
  • A myelodysplastic syndrome characterized by bi-cytopenia or pancytopenia, dysplastic changes in 10% or more of the cells in two or more of the myeloid cell lines, and 15% or more ringed sideroblasts in the bone marrow. (who, 2001)
ICD-10-CM D46.B is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 811 Red blood cell disorders with mcc
  • 812 Red blood cell disorders without mcc

Convert D46.B to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to D46.B:
  • Cytopenia D75.9
    ICD-10-CM Diagnosis Code D75.9

    Disease of blood and blood-forming organs, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    • refractory
      • with multilineage dysplasia D46.A
        ICD-10-CM Diagnosis Code D46.A

        Refractory cytopenia with multilineage dysplasia

          2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
        • and ring sideroblasts D46.B (RCMD RS)
  • Syndrome - see also Disease
    • myelodysplastic D46.9
      ICD-10-CM Diagnosis Code D46.9

      Myelodysplastic syndrome, unspecified

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      Applicable To
      • Myelodysplasia NOS
      • with
        • multilineage dysplasia D46.A
          ICD-10-CM Diagnosis Code D46.A

          Refractory cytopenia with multilineage dysplasia

            2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
          • with ringed sideroblasts D46.B

ICD-10-CM Codes Adjacent To D46.B
D44.9 Neoplasm of uncertain behavior of unspecified endocrine gland
D45 Polycythemia vera
D46 Myelodysplastic syndromes
D46.0 Refractory anemia without ring sideroblasts, so stated
D46.1 Refractory anemia with ring sideroblasts
D46.2 Refractory anemia with excess of blasts [RAEB]
D46.20 Refractory anemia with excess of blasts, unspecified
D46.21 Refractory anemia with excess of blasts 1
D46.22 Refractory anemia with excess of blasts 2
D46.A Refractory cytopenia with multilineage dysplasia
D46.B Refractory cytopenia with multilineage dysplasia and ring sideroblasts
D46.C Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
D46.4 Refractory anemia, unspecified
D46.Z Other myelodysplastic syndromes
D46.9 Myelodysplastic syndrome, unspecified
D47 Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
D47.0 Mast cell neoplasms of uncertain behavior
D47.01 Cutaneous mastocytosis
D47.02 Systemic mastocytosis
D47.09 Other mast cell neoplasms of uncertain behavior
D47.1 Chronic myeloproliferative disease

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.