ICD-10-CM Codes
C00-D49 Neoplasms
D49-D49 Neoplasms of unspecified behavior
D49- Neoplasms of unspecified behavior
2022 ICD-10-CM Diagnosis Code D49.9

2022 ICD-10-CM Diagnosis Code D49.9

Neoplasm of unspecified behavior of unspecified site

2016

2017

2018

2019

2020

2021

2022

Billable/Specific Code

D49.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
The 2022 edition of ICD-10-CM D49.9 became effective on October 1, 2021.
This is the American ICD-10-CM version of D49.9 - other international versions of ICD-10 D49.9 may differ.

The following code(s) above D49.9 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to D49.9:

C00-D49
2022 ICD-10-CM Range C00-D49
Neoplasms
Note
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
Neoplasms
D49
ICD-10-CM Diagnosis Code D49
Neoplasms of unspecified behavior
Includes
- 'growth' NOS
- neoplasm NOS
- new growth NOS
- tumor NOS
Note
- Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term 'mass', unless otherwise stated, is not to be regarded as a neoplastic growth.
Type 1 Excludes
- neoplasms of uncertain behavior (D37-D44, D48)
Neoplasms of unspecified behavior

Approximate Synonyms

Anemia in neoplastic disease
Anemia, neoplastic
Bilateral visual pathway disorder due to neoplasm
Dermatomyositis with malignant disease
Dermatomyositis with neoplastic disease
Disorder of optic chiasm due to neoplasm
Disorder of visual pathways associated with neoplasm
Germ cell tumor
Giant cell tumor
Hypercortisolism due to nonpituitary tumor
Myelopathy due to neoplastic disease
Myelopathy in neoplasm of unspecified nature
Neoplasm
Neoplasm, germ cell tumor
Neoplastic disease
Optic chiasm disorder assoc with neoplasm
Osteitis deformans in neoplastic disease
Osteitis deformans of multiple sites in neoplastic disease
Paraneoplastic polyneuropathy
Polyneuropathy (multiple nerve disorder)
Visual pathway disorder assoc with neoplasm

ICD-10-CM D49.9 is grouped within Diagnostic Related Group(s) (MS-DRG v39.0):

826 Myeloproliferative disorders or poorly differentiated neoplasms with major o.r. Procedures with mcc
827 Myeloproliferative disorders or poorly differentiated neoplasms with major o.r. Procedures with cc
828 Myeloproliferative disorders or poorly differentiated neoplasms with major o.r. Procedures without cc/mcc
829 Myeloproliferative disorders or poorly differentiated neoplasms with other procedures with cc/mcc
830 Myeloproliferative disorders or poorly differentiated neoplasms with other procedures without cc/mcc
843 Other myeloproliferative disorders or poorly differentiated neoplastic diagnoses with mcc
844 Other myeloproliferative disorders or poorly differentiated neoplastic diagnoses with cc
845 Other myeloproliferative disorders or poorly differentiated neoplastic diagnoses without cc/mcc

Convert D49.9 to ICD-9-CM

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change

Diagnosis Index entries containing back-references to D49.9:

Arthropathy M12.9
- see also Arthritis
ICD-10-CM Diagnosis Code M12.9
Arthropathy, unspecified
- in (due to)
  - neoplastic disease NOS D49.9 (see also Neoplasm)
Ataxia, ataxy, ataxic R27.0
ICD-10-CM Diagnosis Code R27.0
Ataxia, unspecified
Type 1 Excludes
ataxia following cerebrovascular disease (I69. with final characters -93)
- cerebellar (hereditary) G11.9
  ICD-10-CM Diagnosis Code G11.9
  Hereditary ataxia, unspecified
  2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
  Applicable To
  Hereditary cerebellar ataxia NOS
  Hereditary cerebellar degeneration
  Hereditary cerebellar disease
  Hereditary cerebellar syndrome
  - in
    - neoplastic disease D49.9 - see also Neoplasm
Atrophy, atrophic (of)
- systemic affecting central nervous system
  - in
    - neoplastic disease D49.9 - see also Neoplasm
Compression
- nerve G58.9
  - see also Disorder, nerve
  ICD-10-CM Diagnosis Code G58.9
  Mononeuropathy, unspecified
  2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
  - root or plexus NOS (in) G54.9
    ICD-10-CM Diagnosis Code G54.9
    Nerve root and plexus disorder, unspecified
    2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    - neoplastic disease D49.9 - see also Neoplasm
Dermatomyositis (acute) (chronic) - see also Dermatopolymyositis
- in D49.9 (due to) - see also Neoplasm
Dermatopolymyositis M33.90
ICD-10-CM Diagnosis Code M33.90
Dermatopolymyositis, unspecified, organ involvement unspecified
- in neoplastic disease D49.9 - see also Neoplasm
Encephalopathy (acute) G93.40
ICD-10-CM Diagnosis Code G93.40
Encephalopathy, unspecified
- in (due to) (with)
  - neoplastic disease D49.9 (see also Neoplasm)
Myasthenia G70.9
ICD-10-CM Diagnosis Code G70.9
Myoneural disorder, unspecified
- syndrome
  - in
    - neoplastic disease D49.9 - see also Neoplasm
Myelopathy (spinal cord) G95.9
ICD-10-CM Diagnosis Code G95.9
Disease of spinal cord, unspecified
Applicable To
Myelopathy NOS
- in (due to)
  - neoplastic disease D49.9 - see also Neoplasm
Neuromyopathy G70.9
ICD-10-CM Diagnosis Code G70.9
Myoneural disorder, unspecified
- paraneoplastic D49.9
Neuropathy, neuropathic G62.9
ICD-10-CM Diagnosis Code G62.9
Polyneuropathy, unspecified
Applicable To
Neuropathy NOS
- paraneoplastic D49.9 (sensorial) (Denny Brown)
Osteitis - see also Osteomyelitis
- deformans M88.9
  ICD-10-CM Diagnosis Code M88.9
  Osteitis deformans of unspecified bone
  2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
  - in (due to)
    - neoplastic disease D49.9 - see also Neoplasm
      - carpus D49.9
      - clavicle D49.9
      - femur D49.9
      - fibula D49.9
      - finger D49.9
      - humerus D49.9
      - ilium D49.9
      - ischium D49.9
      - metacarpus D49.9
      - metatarsus D49.9
      - multiple sites D49.9
      - neck D49.9
      - radius D49.9
      - rib D49.9
      - scapula D49.9
      - skull D49.9
      - tarsus D49.9
      - tibia D49.9
      - toe D49.9
      - ulna D49.9
      - vertebra D49.9
Palsy G83.9
- see also Paralysis
ICD-10-CM Diagnosis Code G83.9
Paralytic syndrome, unspecified
- cranial nerve - see also Disorder, nerve, cranial
  - multiple G52.7
    ICD-10-CM Diagnosis Code G52.7
    Disorders of multiple cranial nerves
    2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Applicable To
    Polyneuritis cranialis
    - in
      - neoplastic disease D49.9 - see also Neoplasm
Polyneuropathy (peripheral) G62.9
ICD-10-CM Diagnosis Code G62.9
Polyneuropathy, unspecified
Applicable To
Neuropathy NOS
- in (due to)
  - neoplastic disease D49.9 - see also Neoplasm
Syndrome - see also Disease
- myasthenic G70.9
  ICD-10-CM Diagnosis Code G70.9
  Myoneural disorder, unspecified
  2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
  - in
    - neoplastic disease D49.9 - see also Neoplasm

ICD-10-CM Codes Adjacent To D49.9

D49.51 Neoplasm of unspecified behavior of kidney

D49.511 Neoplasm of unspecified behavior of right kidney

D49.512 Neoplasm of unspecified behavior of left kidney

D49.519 Neoplasm of unspecified behavior of unspecified kidney

D49.59 Neoplasm of unspecified behavior of other genitourinary organ

D49.6 Neoplasm of unspecified behavior of brain

D49.7 Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system

D49.8 Neoplasm of unspecified behavior of other specified sites

D49.81 Neoplasm of unspecified behavior of retina and choroid

D49.89 Neoplasm of unspecified behavior of other specified sites

D49.9 Neoplasm of unspecified behavior of unspecified site

D50 Iron deficiency anemia

D50.0 Iron deficiency anemia secondary to blood loss (chronic)

D50.1 Sideropenic dysphagia

D50.8 Other iron deficiency anemias

D50.9 Iron deficiency anemia, unspecified

D51 Vitamin B12 deficiency anemia

D51.0 Vitamin B12 deficiency anemia due to intrinsic factor deficiency

D51.1 Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria

D51.2 Transcobalamin II deficiency

D51.3 Other dietary vitamin B12 deficiency anemia

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2022 ICD-10-CM Diagnosis Code D49.9

Neoplasm of unspecified behavior of unspecified site

Neoplasms

Neoplasms of unspecified behavior

Arthropathy, unspecified

Ataxia, unspecified

Hereditary ataxia, unspecified

Mononeuropathy, unspecified

Nerve root and plexus disorder, unspecified

Dermatopolymyositis, unspecified, organ involvement unspecified

Encephalopathy, unspecified

Myoneural disorder, unspecified

Disease of spinal cord, unspecified

Myoneural disorder, unspecified

Polyneuropathy, unspecified

Osteitis deformans of unspecified bone

Paralytic syndrome, unspecified

Disorders of multiple cranial nerves

Polyneuropathy, unspecified

Myoneural disorder, unspecified