1. ICD-10-CM Codes
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2. D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
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3. D50-D53 Nutritional anemias
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4. D51- Vitamin B12 deficiency anemia
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5. 2021 ICD-10-CM Diagnosis Code D51.0

2021 ICD-10-CM Diagnosis Code D51.0

Vitamin B12 deficiency anemia due to intrinsic factor deficiency

2016 2017 2018 2019 2020 2021 Billable/Specific Code

• D51.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• Short description: Vitamin B12 defic anemia due to intrinsic factor deficiency
• The 2021 edition of ICD-10-CM D51.0 became effective on October 1, 2020.
• This is the American ICD-10-CM version of D51.0 - other international versions of ICD-10 D51.0 may differ.

• Anemia, pernicious
• Pernicious anemia

• A decrease in red blood cells that occurs when the body cannot absorb vitamin b12
• A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin b 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed)
• A type of anemia (low red blood cell count) caused by the body's inability to absorb vitamin b12.
• Anemia due to poor intestinal absorption of vitamin b12 caused by defective production of intrinsic factor (a carrier protein) by the gastric mucosa.
• Megaloblastic anemia caused by vitamin b-12 deficiency due to impaired absorption. The impaired absorption of vitamin b-12 is secondary to atrophic gastritis and loss of gastric parietal cells.

• 811 Red blood cell disorders with mcc
• 812 Red blood cell disorders without mcc

Convert D51.0 to ICD-9-CM

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change

• Code First: G32.0
  ICD-10-CM Diagnosis Code G32.0

  Subacute combined degeneration of spinal cord in diseases classified elsewhere

  2016 2017 2018 2019 2020 2021 Billable/Specific Code Manifestation Code

  Applicable To

  • Dana-Putnam syndrome
  • Sclerosis of spinal cord (combined) (dorsolateral) (posterolateral)

  Code First

  • underlying disease, such as:
  • anemia (D51.9)
  • dietary (D51.3)
  • pernicious (D51.0)
  • vitamin B12 deficiency (E53.8)

  Type 1 Excludes

  • syphilitic combined degeneration of spinal cord (A52.11)

• Addison-Biermer anemia D51.0 (pernicious)
• Addison's
  • anemia D51.0 (pernicious)
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
  ICD-10-CM Diagnosis Code D64.9

  Anemia, unspecified

  2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • combined system disease NEC D51.0
  • congenital P61.4
    ICD-10-CM Diagnosis Code P61.4

    Other congenital anemias, not elsewhere classified

    2016 2017 2018 2019 2020 2021 Billable/Specific Code Code on Newborn Record

    Applicable To

    • Congenital anemia NOS
    • pernicious D51.0
  • deficiency D53.9
    ICD-10-CM Diagnosis Code D53.9

    Nutritional anemia, unspecified

    2016 2017 2018 2019 2020 2021 Billable/Specific Code

    Applicable To

    • Simple chronic anemia

    Type 1 Excludes

    • anemia NOS (D64.9)
    • vitamin B12 NOS D51.9
      ICD-10-CM Diagnosis Code D51.9

      Vitamin B12 deficiency anemia, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
      • due to
        • intrinsic factor deficiency D51.0
      • pernicious D51.0
  • progressive D64.9
    ICD-10-CM Diagnosis Code D64.9

    Anemia, unspecified

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
    • malignant D51.0
    • pernicious D51.0
  • vitamin
    • B12 deficiency D51.0 (dietary)
  • Addison D51.0 (-Biermer) (pernicious)
  • Biermer's D51.0 (pernicious)
  • cytogenic D51.0
  • malignant D51.0 (progressive)
  • pernicious D51.0 (congenital) (malignant) (progressive)
• Biermer's D51.0 (pernicious)
• Congenital - see also condition
  • intrinsic factor deficiency D51.0
• Deficiency, deficient
  • intrinsic
    • factor D51.0 (congenital)
• Degeneration, degenerative
  • combined (spinal cord) (subacute) E53.8
    ICD-10-CM Diagnosis Code E53.8

    Deficiency of other specified B group vitamins

    2016 2017 2018 2019 2020 2021 Billable/Specific Code

    Applicable To

    • Biotin deficiency
    • Cyanocobalamin deficiency
    • Folate deficiency
    • Folic acid deficiency
    • Pantothenic acid deficiency
    • Vitamin B12 deficiency

    Type 1 Excludes

    • folate deficiency anemia (D52.-)
    • vitamin B12 deficiency anemia (D51.-)
    • with anemia (pernicious) D51.0
• Disease, diseased - see also Syndrome
  • Addison's anemia D51.0 (pernicious)
  • Biermer's D51.0 (pernicious anemia)
  • Lichtheim's D51.0 (subacute combined sclerosis with pernicious anemia)
  • Putnam's D51.0 (subacute combined sclerosis with pernicious anemia)
  • Runeberg's D51.0 (progressive pernicious anemia)
• Glossitis (chronic superficial) (gangrenous) (Moeller's) K14.0
  ICD-10-CM Diagnosis Code K14.0

  Glossitis

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Applicable To

  • Abscess of tongue
  • Ulceration (traumatic) of tongue

  Type 1 Excludes

  • atrophic glossitis (K14.4)
  • Hunter's D51.0
• Hunter's
  • glossitis D51.0
• Lichtheim's disease or syndrome D51.0
• Myasthenia G70.9
  ICD-10-CM Diagnosis Code G70.9

  Myoneural disorder, unspecified

  2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • syndrome
    • in
      • pernicious anemia D51.0
• Myelopathy (spinal cord) G95.9
  ICD-10-CM Diagnosis Code G95.9

  Disease of spinal cord, unspecified

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Applicable To

  • Myelopathy NOS
  • in (due to)
    • pernicious anemia D51.0
• Neuropathy, neuropathic G62.9
  ICD-10-CM Diagnosis Code G62.9

  Polyneuropathy, unspecified

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Applicable To

  • Neuropathy NOS
  • vitamin B12 E53.8
    ICD-10-CM Diagnosis Code E53.8

    Deficiency of other specified B group vitamins

    2016 2017 2018 2019 2020 2021 Billable/Specific Code

    Applicable To

    • Biotin deficiency
    • Cyanocobalamin deficiency
    • Folate deficiency
    • Folic acid deficiency
    • Pantothenic acid deficiency
    • Vitamin B12 deficiency

    Type 1 Excludes

    • folate deficiency anemia (D52.-)
    • vitamin B12 deficiency anemia (D51.-)
    • with anemia (pernicious) D51.0
• Polyneuropathy (peripheral) G62.9
  ICD-10-CM Diagnosis Code G62.9

  Polyneuropathy, unspecified

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Applicable To

  • Neuropathy NOS
  • transthyretin-related (ATTR) E85.1
    ICD-10-CM Diagnosis Code E85.1

    Neuropathic heredofamilial amyloidosis

    2016 2017 2018 2019 2020 2021 Billable/Specific Code

    Applicable To

    • Amyloid polyneuropathy (Portuguese)
    • Transthyretin-related (ATTR) familial amyloid polyneuropathy
    • vitamin B12 deficiency E53.8
      ICD-10-CM Diagnosis Code E53.8

      Deficiency of other specified B group vitamins

      2016 2017 2018 2019 2020 2021 Billable/Specific Code

      Applicable To

      • Biotin deficiency
      • Cyanocobalamin deficiency
      • Folate deficiency
      • Folic acid deficiency
      • Pantothenic acid deficiency
      • Vitamin B12 deficiency

      Type 1 Excludes

      • folate deficiency anemia (D52.-)
      • vitamin B12 deficiency anemia (D51.-)
      • with anemia (pernicious) D51.0
• Runeberg's disease D51.0
• Syndrome - see also Disease
  • Dana-Putnam D51.0
  • hunterian glossitis D51.0
  • Lichtheim's D51.0
  • Putnam-Dana D51.0

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.