ICD-10-CM Codes
D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
D55-D59 Hemolytic anemias
D55- Anemia due to enzyme disorders
2020 ICD-10-CM Diagnosis Code D55

2020 ICD-10-CM Diagnosis Code D55

Anemia due to enzyme disorders

2016

2017

2018

2019

2020

Non-Billable/Non-Specific Code

D55 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
The 2020 edition of ICD-10-CM D55 became effective on October 1, 2019.
This is the American ICD-10-CM version of D55 - other international versions of ICD-10 D55 may differ.

Type 1 Excludes

Type 1 Excludes Help

A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D55. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

drug-induced enzyme deficiency anemia (
ICD-10-CM Diagnosis Code D59.2
Drug-induced nonautoimmune hemolytic anemia
Applicable To
- Drug-induced enzyme deficiency anemia
Use Additional
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
D59.2
)

The following code(s) above D55 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to D55:

D50-D89
2020 ICD-10-CM Range D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Type 2 Excludes
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change

Code annotations containing back-references to D55:

Type 1 Excludes: E74.4

ICD-10-CM Diagnosis Code E74.4
Disorders of pyruvate metabolism and gluconeogenesis
Applicable To
- Deficiency of phosphoenolpyruvate carboxykinase
- Deficiency of pyruvate carboxylase
- Deficiency of pyruvate dehydrogenase
Type 1 Excludes
- disorders of pyruvate metabolism and gluconeogenesis with anemia (D55.-)
- Leigh's syndrome (G31.82)

ICD-10-CM Codes Adjacent To D55

D52.0 Dietary folate deficiency anemia

D52.1 Drug-induced folate deficiency anemia

D52.8 Other folate deficiency anemias

D52.9 Folate deficiency anemia, unspecified

D53 Other nutritional anemias

D53.0 Protein deficiency anemia

D53.1 Other megaloblastic anemias, not elsewhere classified

D53.2 Scorbutic anemia

D53.8 Other specified nutritional anemias

D53.9 Nutritional anemia, unspecified

D55 Anemia due to enzyme disorders

D55.0 Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency

D55.1 Anemia due to other disorders of glutathione metabolism

D55.2 Anemia due to disorders of glycolytic enzymes

D55.3 Anemia due to disorders of nucleotide metabolism

D55.8 Other anemias due to enzyme disorders

D55.9 Anemia due to enzyme disorder, unspecified

D56 Thalassemia

D56.0 Alpha thalassemia

D56.1 Beta thalassemia

D56.2 Delta-beta thalassemia

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2020 ICD-10-CM Diagnosis Code D55

Anemia due to enzyme disorders

Drug-induced nonautoimmune hemolytic anemia

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Disorders of pyruvate metabolism and gluconeogenesis