2020 ICD-10-CM Diagnosis Code D55.2

Anemia due to disorders of glycolytic enzymes

    2016 2017 2018 2019 2020 Billable/Specific Code
  • D55.2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM D55.2 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of D55.2 - other international versions of ICD-10 D55.2 may differ.
Applicable To
  • Hemolytic nonspherocytic (hereditary) anemia, type II
  • Hexokinase deficiency anemia
  • Pyruvate kinase [PK] deficiency anemia
  • Triose-phosphate isomerase deficiency anemia
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D55.2. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • disorders of glycolysis not associated with anemia (
    ICD-10-CM Diagnosis Code E74.8

    Other specified disorders of carbohydrate metabolism

      2016 2017 2018 2019 2020 Billable/Specific Code
    Applicable To
    • Essential pentosuria
    • Renal glycosuria
    E74.8
    )
The following code(s) above D55.2 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D55.2:
  • D50-D89
    2020 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D55
    ICD-10-CM Diagnosis Code D55

    Anemia due to enzyme disorders

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • drug-induced enzyme deficiency anemia (D59.2)
    Anemia due to enzyme disorders
ICD-10-CM D55.2 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 811 Red blood cell disorders with mcc
  • 812 Red blood cell disorders without mcc

Convert D55.2 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change

Diagnosis Index entries containing back-references to D55.2:
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
    ICD-10-CM Diagnosis Code D64.9

    Anemia, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    • with (due to) (in)
    • deficiency D53.9
      ICD-10-CM Diagnosis Code D53.9

      Nutritional anemia, unspecified

        2016 2017 2018 2019 2020 Billable/Specific Code
      Applicable To
      • Simple chronic anemia
      Type 1 Excludes
      • enzyme D55.9
        ICD-10-CM Diagnosis Code D55.9

        Anemia due to enzyme disorder, unspecified

          2016 2017 2018 2019 2020 Billable/Specific Code
        • glycolytic D55.2
      • 2, 3 diphosphoglycurate mutase D55.2
      • 2, 3 PG D55.2
      • glyceraldehyde phosphate dehydrogenase D55.2
      • hexokinase D55.2
      • phosphofructo-aldolase D55.2
      • phosphoglycerate kinase D55.2
      • PK D55.2
      • pyruvate kinase D55.2
      • triose-phosphate isomerase D55.2
    • hemolytic D58.9
      ICD-10-CM Diagnosis Code D58.9

      Hereditary hemolytic anemia, unspecified

        2016 2017 2018 2019 2020 Billable/Specific Code
    • hexokinase deficiency D55.2
    • pyruvate kinase deficiency D55.2
  • Disorder (of) - see also Disease
    • anaerobic glycolysis with anemia D55.2

ICD-10-CM Codes Adjacent To D55.2
D52.9 Folate deficiency anemia, unspecified
D53 Other nutritional anemias
D53.0 Protein deficiency anemia
D53.1 Other megaloblastic anemias, not elsewhere classified
D53.2 Scorbutic anemia
D53.8 Other specified nutritional anemias
D53.9 Nutritional anemia, unspecified
D55 Anemia due to enzyme disorders
D55.0 Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
D55.1 Anemia due to other disorders of glutathione metabolism
D55.2 Anemia due to disorders of glycolytic enzymes
D55.3 Anemia due to disorders of nucleotide metabolism
D55.8 Other anemias due to enzyme disorders
D55.9 Anemia due to enzyme disorder, unspecified
D56 Thalassemia
D56.0 Alpha thalassemia
D56.1 Beta thalassemia
D56.2 Delta-beta thalassemia
D56.3 Thalassemia minor
D56.4 Hereditary persistence of fetal hemoglobin [HPFH]
D56.5 Hemoglobin E-beta thalassemia

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.